Search Results - "Egom, Emmanuel E"
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The potential actions of angiotensin‐converting enzyme II (ACE2) activator diminazene aceturate (DIZE) in various diseases
Published in Clinical and experimental pharmacology & physiology (01-05-2020)“…The renin angiotensin system (RAS) regulates fluid balance, blood pressure and maintains vascular tone. The potent vasoconstrictor angiotensin II (Ang II)…”
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Updates on sphingolipids: Spotlight on retinopathy
Published in Biomedicine & pharmacotherapy (01-11-2021)“…The sphingolipids ceramide (Cer), ceramide-1-phosphate (C1P), sphingosine (Sph), and sphingosine-1-phosphate (S1P)) are key signaling molecules that regulate…”
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Markers of Atherosclerosis: Part 1 – Serological Markers
Published in Heart, lung & circulation (01-05-2019)“…Atherosclerosis is a major contributor to morbidity and mortality worldwide. With therapeutic consequences in mind, several risk scores are being used to…”
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Markers of Atherosclerosis: Part 2 – Genetic and Imaging Markers
Published in Heart, lung & circulation (01-05-2019)“…This is Part 2 of a two-part review summarising current knowledge on biomarkers of atherosclerosis. Part 1 addressed serological biomarkers. Here, in part 2 we…”
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HDL-C/HDL-P Ratio
Published in Journal of the American College of Cardiology (16-06-2015)“…[...]recent evidence also suggests that the overall HDL-P is not as important as a determinant of residual cardiovascular risk as the number of HDL-P, which…”
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Determination of Sphingosine-1-Phosphate in Human Plasma Using Liquid Chromatography Coupled with Q-Tof Mass Spectrometry
Published in International journal of molecular sciences (18-08-2017)“…Evidence suggests that high-density lipoprotein (HDL) components distinct from cholesterol, such as sphingosine-1-phosphate (S1P), may account for the…”
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Natriuretic Peptide Receptor-C Protects Against Angiotensin II-Mediated Sinoatrial Node Disease in Mice
Published in JACC. Basic to translational science (01-12-2018)“…Visual Abstract…”
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Mechanisms of renal hyporesponsiveness to BNP in heart failure
Published in Canadian journal of physiology and pharmacology (01-06-2015)“…The B-type natriuretic peptide (BNP), a member of the family of vasoactive peptides, is a potent natriuretic, diuretic, and vasodilatory peptide that…”
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LDL-Cholesterol and Atherosclerotic Cardiovascular Disease: Innocent Bystander or Essential Ingredient
Published in Journal of the American College of Cardiology (13-02-2018)Get full text
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TRP channels in gastric cancer: New hopes and clinical perspectives
Published in Cell calcium (Edinburgh) (01-09-2019)“…Graphical Abstract: Schematic depiction of the current and emerging therapies for gastric cancer patients. Surgery has long been the therapy of choice for…”
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The potential role of sphingolipid-mediated cell signaling in the interaction between hyperglycemia, acute myocardial infarction and heart failure
Published in Expert opinion on therapeutic targets (01-08-2012)“…Patients with acute myocardial infarction or heart failure frequently have abnormalities of glucose metabolism and insulin resistance, both of which are…”
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HDL-C/HDL-P Ratio: A Measure of Reverse Cholesterol Transport Rather Than HDL Functionality
Published in Journal of the American College of Cardiology (16-06-2015)Get full text
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Ezetimibe plus a Statin after Acute Coronary Syndromes
Published in The New England journal of medicine (08-10-2015)Get full text
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Loss of insulin signaling may contribute to atrial fibrillation and atrial electrical remodeling in type 1 diabetes
Published in Proceedings of the National Academy of Sciences - PNAS (07-04-2020)“…Atrial fibrillation (AF) is prevalent in diabetes mellitus (DM); however, the basis for this is unknown. This study investigated AF susceptibility and atrial…”
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Evolving use of natriuretic peptide receptor type-C as part of strategies for the treatment of pulmonary hypertension due to left ventricle heart failure
Published in International journal of cardiology (15-04-2019)“…Pulmonary hypertension (PH) due to left ventricular heart failure (LV-HF) is a disabling and life-threatening disease for which there is currently no single…”
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Distinct patterns of atrial electrical and structural remodeling in angiotensin II mediated atrial fibrillation
Published in Journal of molecular and cellular cardiology (01-11-2018)“…Atrial fibrillation (AF) is prevalent in hypertension and elevated angiotensin II (Ang II); however, the mechanisms by which Ang II leads to AF are poorly…”
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Simvastatin in moderate-to-severe COPD
Published in The New England journal of medicine (04-09-2014)Get full text
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BNP and Heart Failure: Preclinical and Clinical Trial Data
Published in Journal of cardiovascular translational research (01-04-2015)“…The B-type natriuretic peptide (BNP), a member of the family of vasoactive peptides, has emerged as an important diagnostic, prognostic, and therapeutic tool…”
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Riociguat for pulmonary hypertension
Published in The New England journal of medicine (05-12-2013)Get full text
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