Search Results - "Eglitis, Martin A."

Hematopoietic Cells Differentiate into Both Microglia and Macroglia in the Brains of Adult Mice by Eglitis, Martin A., Mezey, Eva

“…Glial cells are thought to derive embryologically from either myeloid cells of the hematopoietic system (microglia) or neuroepithelial progenitor cells…”
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Targeting of marrow-derived astrocytes to the ischemic brain by Eglitis, Martin A, Dawson, Debbie, Park, Kun-Woo, Mouradian, M Maral

“…BONE marrow progenitor cells have been shown to contribute to a small proportion of cells in nonhematopoietic tissues including the brain. In the acute…”
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Protection of nigral neurons by GDNF-engineered marrow cell transplantation by Park, Kun-Woo, Eglitis, Martin A., Mouradian, M.Maral

“…Marrow stromal cells, which have many characteristics of stem cells, populate various non-hematopoietic tissues including the brain. In the present study, the…”
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Factors affecting retroviral vector function and structural integrity by McLachlin, J R, Mittereder, N, Daucher, M B, Kadan, M, Eglitis, M A

“…Recombinant retroviruses are widely used for gene transfer into eukaryotic cells and exhibit significant potential for human gene therapy. Despite the utility…”
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Gene Expression in Mice after High Efficiency Retroviral-Mediated Gene Transfer by Eglitis, Martin A., Kantoff, Philip, Gilboa, Eli, Anderson, W. French

“…A retroviral expression vector (N2) containing the selectable gene, neo$^{R}$, has been used to determine the optimal conditions for infecting murine…”
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Effects of colcemid on cavitation during mouse blastocoele formation by Wiley, L M, Eglitis, M A

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Tetraploidy and early development: effects on developmental timing and embryonic metabolism by Eglitis, M A, Wiley, L M

“…The effect of balanced gene dosage changes on the timing of cavitation and on the timing of appearance of a stage-specific embryonic cell surface antigen was…”
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Reversible and irreversible effects of retinol upon the phenotypic properties of embryonal carcinoma cells by SHERMAN, M. I, EGLITIS, M. A, THOMAS, R

“…We have generated an embryonal carcinoma cell line, NR1, which is not growth-inhibited in response to retinol. Although the retinol-treated cells undergo…”
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Detection of receptor-specific murine leukemia virus binding to cells by immunofluorescence analysis by KADAN, M. J, STURM, S, ANDERSON, W. F, EGLITIS, M. A

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Positive selectable markers for use with mammalian cells in culture by Eglitis, M A

“…As more complicated gene expression studies are necessary, the need for multiple positive selection schemes becomes critical. Numerous selectable markers have…”
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Transduction of Human Hematopoietic Progenitor Cells with Retroviral Vectors Based on the Gibbon Ape Leukemia Virus by Eglitis, Martin A., Schneiderman, Richard D.

“…Gene transfer into human hematopoietic stem cells continues to be complicated by issues of transfer efficiency. We have examined the capacity of newly…”
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Transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA-deficient SCID by Bordignon, C, Mavilio, F, Ferrari, G, Servida, P, Ugazio, A G, Notarangelo, L D, Gilboa, E, Rossini, S, O'Reilly, R J, Smith, C A

“…Severe combined immunodeficiency (SCID) caused by deficiency of the enzyme adenosine deaminase (ADA) is the first genetic disorder considered for human somatic…”
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Expression of human adenosine deaminase in nonhuman primates after retrovirus-mediated gene transfer by KANTOFF, P. W, GILLIO, A. P, KARLSSON, S, SWIEBEL, J. A, GILBOA, E, BLAESE, R. M, NIENHUIS, A, O'REILLY, R. J, FRENCH ANDERSON, W, MCLACHLIN, J. R, BORDIGNON, C, EGLITIS, M. A, KERNAN, N. A, MOEN, R. C, KOHN, D. B, SHEAU-FUNG YU, KARSON, E

“…Primate bone marrow cells were infected with a retroviral vector carrying the genes for human adenosine deaminase (h-ADA) and bacterial neomycin resistance…”
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Expression of a human complementary DNA for the multidrug resistance gene in murine hematopoietic precursor cells with the use of retroviral gene transfer by McLachlin, J R, Eglitis, M A, Ueda, K, Kantoff, P W, Pastan, I H, Anderson, W F, Gottesman, M M

“…In multidrug resistance, cells become simultaneously resistant to anthracyclines, vinca alkaloids, epipodophyllotoxins, and certain other natural product…”
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Gibbon ape leukemia virus and the amphotropic murine leukemia virus 4070A exhibit an unusual interference pattern on E36 Chinese hamster cells by EGLITIS, M. A, EIDEN, M. V, WILSON, C. A

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Correction of Adenosine Deaminase Deficiency in Cultured Human T and B Cells by Retrovirus-Mediated Gene Transfer by Kantoff, Philip W., Kohn, Donald B., Mitsuya, Hiroaki, Armentano, Donna, Sieberg, Miri, Zwiebel, James A., Eglitis, Martin A., McLachlin, Jeanne R., Wiginton, Dan A., Hutton, John J., Horowitz, Sheldon D., Gilboa, Eli, Blaese, R. Michael, Anderson, W. French

“…A retroviral vector called SAX, containing the cloned human cDNA for adenosine deaminase (ADA), has been constructed and used to introduce the ADA gene into…”
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Expression of a Foreign Gene in Cats Reconstituted With Retroviral Vector Infected Autologous Bone Marrow by Lothrop, Clinton D., Al-Lebban, Zuhair S., Niemeyer, Glenn P., Jones, J.B., Peterson, M.G., Smith, Joey R., Baker, Henry J., Morgan, Richard A., Eglitis, Martin A., Anderson, W.French

“…A Moloney murine leukemia virus based retroviral vector was used to transfer the bacterial neomycin resistance gene (neoR) into feline hematopoietic cells. We…”
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In Utero Gene Transfer and Expression: A Sheep Transplantation Model by Kantoff, Philip W., Flake, Alan W., Eglitis, Martin A., Scharf, Stephen, Bond, Sheldon, Gilboa, Eli, Erlich, Henry, Harrison, Michael R., Zanjani, Esmail D., Anderson, W. French

“…Retroviral-mediated gene transfer was used to insert a Neo R gene into fetal sheep hematopoietic cells obtained by exchange transfusion from lambs in utero…”
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Murine embryonal carcinoma cells differentiate in vitro in response to retinol by Eglitis, M A, Sherman, M I

“…In an initial effort to determine whether circulating retinol might promote differentiation of embryonal carcinoma (EC) cells in tumor form, we have assessed…”
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Cell surface and cytoskeletal elements: Cavitation in the mouse preimplantation embryo by Wiley, Lynn M., Eglitis, Martin A.

“…Cavitation is the process whereby the mouse preimplantation embryo develops a fluid-filled blastocoele. Prior to the appearance of the blastocoele fluid, when…”
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