Search Results - "Eglitis, M A"

Enhanced vulnerability to oxidative stress by α-synuclein mutations and C-terminal truncation by Kanda, S, Bishop, J.F, Eglitis, M.A, Yang, Y, Mouradian, M.M

“…α-Synuclein is a key component of Lewy bodies found in the brains of patients with Parkinson’s disease and two point mutations in this protein, Ala53Thr and…”
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Targeting of marrow-derived astrocytes to the ischemic brain by Eglitis, Martin A, Dawson, Debbie, Park, Kun-Woo, Mouradian, M Maral

“…BONE marrow progenitor cells have been shown to contribute to a small proportion of cells in nonhematopoietic tissues including the brain. In the acute…”
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Brain-derived neurotrophic factor (BDNF) gene delivery into the CNS using bone marrow cells as vehicles in mice by Makar, T.K., Trisler, D., Eglitis, M.A., Mouradian, M.M., Dhib-Jalbut, S.

“…Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is protective in animal models of neurodegenerative diseases. However, BDNF has…”
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Hematopoietic Cells Differentiate into Both Microglia and Macroglia in the Brains of Adult Mice by Eglitis, Martin A., Mezey, Eva

“…Glial cells are thought to derive embryologically from either myeloid cells of the hematopoietic system (microglia) or neuroepithelial progenitor cells…”
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Detection of receptor-specific murine leukemia virus binding to cells by immunofluorescence analysis by KADAN, M. J, STURM, S, ANDERSON, W. F, EGLITIS, M. A

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Factors affecting retroviral vector function and structural integrity by McLachlin, J R, Mittereder, N, Daucher, M B, Kadan, M, Eglitis, M A

“…Recombinant retroviruses are widely used for gene transfer into eukaryotic cells and exhibit significant potential for human gene therapy. Despite the utility…”
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Gene Expression in Mice after High Efficiency Retroviral-Mediated Gene Transfer by Eglitis, Martin A., Kantoff, Philip, Gilboa, Eli, Anderson, W. French

“…A retroviral expression vector (N2) containing the selectable gene, neo$^{R}$, has been used to determine the optimal conditions for infecting murine…”
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Correction of Adenosine Deaminase Deficiency in Cultured Human T and B Cells by Retrovirus-Mediated Gene Transfer by Kantoff, Philip W., Kohn, Donald B., Mitsuya, Hiroaki, Armentano, Donna, Sieberg, Miri, Zwiebel, James A., Eglitis, Martin A., McLachlin, Jeanne R., Wiginton, Dan A., Hutton, John J., Horowitz, Sheldon D., Gilboa, Eli, Blaese, R. Michael, Anderson, W. French

“…A retroviral vector called SAX, containing the cloned human cDNA for adenosine deaminase (ADA), has been constructed and used to introduce the ADA gene into…”
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Retroviral vectors for introduction of genes into mammalian cells by Eglitis, M A, Anderson, W F

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Gibbon ape leukemia virus and the amphotropic murine leukemia virus 4070A exhibit an unusual interference pattern on E36 Chinese hamster cells by EGLITIS, M. A, EIDEN, M. V, WILSON, C. A

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In Utero Gene Transfer and Expression: A Sheep Transplantation Model by Kantoff, Philip W., Flake, Alan W., Eglitis, Martin A., Scharf, Stephen, Bond, Sheldon, Gilboa, Eli, Erlich, Henry, Harrison, Michael R., Zanjani, Esmail D., Anderson, W. French

“…Retroviral-mediated gene transfer was used to insert a Neo R gene into fetal sheep hematopoietic cells obtained by exchange transfusion from lambs in utero…”
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Introduction of human genomic sequences renders CHO-K1 cells susceptible to infection by amphotropic retroviruses by EGLITIS, M. A, KADAN, M. J, WONILOWICZ, E, GOULD, L

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Expression of human adenosine deaminase in nonhuman primates after retrovirus-mediated gene transfer by KANTOFF, P. W, GILLIO, A. P, KARLSSON, S, SWIEBEL, J. A, GILBOA, E, BLAESE, R. M, NIENHUIS, A, O'REILLY, R. J, FRENCH ANDERSON, W, MCLACHLIN, J. R, BORDIGNON, C, EGLITIS, M. A, KERNAN, N. A, MOEN, R. C, KOHN, D. B, SHEAU-FUNG YU, KARSON, E

“…Primate bone marrow cells were infected with a retroviral vector carrying the genes for human adenosine deaminase (h-ADA) and bacterial neomycin resistance…”
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Expression of a human complementary DNA for the multidrug resistance gene in murine hematopoietic precursor cells with the use of retroviral gene transfer by McLachlin, J R, Eglitis, M A, Ueda, K, Kantoff, P W, Pastan, I H, Anderson, W F, Gottesman, M M

“…In multidrug resistance, cells become simultaneously resistant to anthracyclines, vinca alkaloids, epipodophyllotoxins, and certain other natural product…”
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Evaluation of retroviral vectors based on the gibbon ape leukemia virus by Eglitis, M A, Schneiderman, R D, Rice, P M, Eiden, M V

“…The gibbon ape leukemia viruses (GaLVs) are primate-derived C-type retroviruses with a broad host range. Using an infectious, full-length clone of the GaLV…”
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Protection of nigral neurons by GDNF-engineered marrow cell transplantation by Park, Kun-Woo, Eglitis, Martin A., Mouradian, M.Maral

“…Marrow stromal cells, which have many characteristics of stem cells, populate various non-hematopoietic tissues including the brain. In the present study, the…”
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Gene Transfer Into Hematopoietic Progenitor Cells From Normal and Cyclic Hematopoietic Dogs Using Retroviral Vectors by Eglitis, Martin A., Kantoff, Phillip W., Jolly, Janet D., Jones, J.B., Anderson, W. French, Lothrop, Clinton D.

“…The Moloney murine leukemia retrovirus-derived vector N2 was used to transfer the bacterial NeoR gene (confer-ring resistance to the neomycin analogue G418)…”
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Expression of a Foreign Gene in Cats Reconstituted With Retroviral Vector Infected Autologous Bone Marrow by Lothrop, Clinton D., Al-Lebban, Zuhair S., Niemeyer, Glenn P., Jones, J.B., Peterson, M.G., Smith, Joey R., Baker, Henry J., Morgan, Richard A., Eglitis, Martin A., Anderson, W.French

“…A Moloney murine leukemia virus based retroviral vector was used to transfer the bacterial neomycin resistance gene (neoR) into feline hematopoietic cells. We…”
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Increased efficiency of gene transfer with retroviral vectors in neonatal hematopoietic progenitor cells by al-Lebban, Z S, Henry, J M, Jones, J B, Eglitis, M A, Anderson, W F, Lothrop, Jr, C D

“…The retroviral vector N2, which is derived from the Moloney murine leukemia retrovirus, was used to transfer the bacterial NeoR gene (conferring resistance to…”
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Reversible and irreversible effects of retinol upon the phenotypic properties of embryonal carcinoma cells by SHERMAN, M. I, EGLITIS, M. A, THOMAS, R

“…We have generated an embryonal carcinoma cell line, NR1, which is not growth-inhibited in response to retinol. Although the retinol-treated cells undergo…”
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