Search Results - "Egils Stalidzans"

OptEnvelope: A target point guided method for growth-coupled production using knockouts by Motamedian, Ehsan, Berzins, Kristaps, Muiznieks, Reinis, Stalidzans, Egils

“…Finding the best knockout strategy for coupling biomass growth and production of a target metabolite using a mathematic model of metabolism is a challenge in…”
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Physiologically based metformin pharmacokinetics model of mice and scale-up to humans for the estimation of concentrations in various tissues by Zake, Darta Maija, Kurlovics, Janis, Zaharenko, Linda, Komasilovs, Vitalijs, Klovins, Janis, Stalidzans, Egils

“…Metformin is the primary drug for type 2 diabetes treatment and a promising candidate for other disease treatment. It has significant deviations between…”
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Sustainable metabolic engineering for sustainability optimisation of industrial biotechnology by Stalidzans, Egils, Dace, Elina

“…Industrial biotechnology represents one of the most innovating and labour-productive industries with an estimated stable economic growth, thus giving space for…”
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Model-based metabolism design: constraints for kinetic and stoichiometric models by Stalidzans, Egils, Seiman, Andrus, Peebo, Karl, Komasilovs, Vitalijs, Pentjuss, Agris

“…The implementation of model-based designs in metabolic engineering and synthetic biology may fail. One of the reasons for this failure is that only a part of…”
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Integrated Sustainability Score Implementation as an Objective Function in Sustainable Metabolic Engineering by Muiznieks, Reinis, Dace, Elina, Stalidzans, Egils

“…The sustainable metabolic engineering (SME) concept was defined by Stalidzans and Dace as an approach to the selection of the most sustainable metabolic…”
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Impact of Waste as a Substrate on Biomass Formation, and Optimization of Spent Microbial Biomass Re-Use by Sustainable Metabolic Engineering by Stikane, Anna, Baumanis, Matiss Ricards, Muiznieks, Reinis, Stalidzans, Egils

“…Biomass residue and waste stream bioconversion is a key pillar for successful transition toward sustainable bioeconomy. Spent microbial biomass (SMB) is a…”
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Kinetic and Stoichiometric Modeling-Based Analysis of Docosahexaenoic Acid (DHA) Production Potential by Crypthecodinium cohnii from Glycerol, Glucose and Ethanol by Berzins, Kristaps, Muiznieks, Reinis, Baumanis, Matiss R, Strazdina, Inese, Shvirksts, Karlis, Prikule, Santa, Galvanauskas, Vytautas, Pleissner, Daniel, Pentjuss, Agris, Grube, Mara, Kalnenieks, Uldis, Stalidzans, Egils

“…Docosahexaenoic acid (DHA) is one of the most important long-chain polyunsaturated fatty acids (LC-PUFAs), with numerous health benefits. , a marine…”
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A Fermentation State Marker Rule Design Task in Metabolic Engineering by Stalidzans, Egils, Muiznieks, Reinis, Dubencovs, Konstantins, Sile, Elina, Berzins, Kristaps, Suleiko, Arturs, Vanags, Juris

“…There are several ways in which mathematical modeling is used in fermentation control, but mechanistic mathematical genome-scale models of metabolism within…”
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Temperature changes above the upper hive body reveal the annual development periods of honey bee colonies by Stalidzans, Egils, Berzonis, Almars

“…► Temperature above the hive body reveal the developmental state of the bee colony. ► Five annual development periods can be recognized automatically. ► One…”
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Closing the loop in bioproduction: Spent microbial biomass as a resource within circular bioeconomy by Stikane, Anna, Dace, Elina, Stalidzans, Egils

“…Successful transition to a circular bioeconomy relies on the availability and efficient use of organic feedstocks such as agricultural and food waste. Advances…”
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IMFLer: A Web Application for Interactive Metabolic Flux Analysis and Visualization by Petrovs, Rudolfs, Stalidzans, Egils, Pentjuss, Agris

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Challenges in the development of Precision Beekeeping by Zacepins, Aleksejs, Brusbardis, Valters, Meitalovs, Jurijs, Stalidzans, Egils

“…Precision Beekeeping (PB), a sub-branch of Precision Agriculture, is an apiary management strategy based on the monitoring of individual bee colonies to…”
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SpaceScanner: COPASI wrapper for automated management of global stochastic optimization experiments by Elsts, Atis, Pentjuss, Agris, Stalidzans, Egils

“…Due to their universal applicability, global stochastic optimization methods are popular for designing improvements of biochemical networks. The drawbacks of…”
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Remote detection of the swarming of honey bee colonies by single-point temperature monitoring by Zacepins, Aleksejs, Kviesis, Armands, Stalidzans, Egils, Liepniece, Marta, Meitalovs, Jurijs

“…Precision Beekeeping (or Precision Apiculture) aims to help beekeepers monitor bee colonies remotely and identify different colony states including deviant…”
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Paint4Net: COBRA Toolbox extension for visualization of stoichiometric models of metabolism by Kostromins, Andrejs, Stalidzans, Egils

“…A visual analysis of reconstructions and large stoichiometric models with elastic change of the visualization scope and representation methods becomes…”
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Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0 by Heirendt, Laurent, Arreckx, Sylvain, Pfau, Thomas, Mendoza, Sebastián N., Richelle, Anne, Heinken, Almut, Haraldsdóttir, Hulda S., Wachowiak, Jacek, Keating, Sarah M., Vlasov, Vanja, Magnusdóttir, Stefania, Ng, Chiam Yu, Preciat, German, Žagare, Alise, Chan, Siu H. J., Aurich, Maike K., Clancy, Catherine M., Modamio, Jennifer, Sauls, John T., Noronha, Alberto, Bordbar, Aarash, Cousins, Benjamin, El Assal, Diana C., Valcarcel, Luis V., Apaolaza, Iñigo, Ghaderi, Susan, Ahookhosh, Masoud, Ben Guebila, Marouen, Kostromins, Andrejs, Sompairac, Nicolas, Le, Hoai M., Ma, Ding, Sun, Yuekai, Wang, Lin, Yurkovich, James T., Oliveira, Miguel A. P., Vuong, Phan T., El Assal, Lemmer P., Kuperstein, Inna, Zinovyev, Andrei, Hinton, H. Scott, Bryant, William A., Aragón Artacho, Francisco J., Planes, Francisco J., Stalidzans, Egils, Maass, Alejandro, Vempala, Santosh, Hucka, Michael, Saunders, Michael A., Maranas, Costas D., Lewis, Nathan E., Sauter, Thomas, Palsson, Bernhard Ø., Thiele, Ines, Fleming, Ronan M. T.

“…Constraint-based reconstruction and analysis (COBRA) provides a molecular mechanistic framework for integrative analysis of experimental molecular systems…”
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Metformin Transport Rates Between Plasma and Red Blood Cells in Humans by Kurlovics, Janis, Zake, Darta Maija, Zaharenko, Linda, Berzins, Kristaps, Klovins, Janis, Stalidzans, Egils

“…Background Metformin has been used for the treatment of type 2 diabetes for over 60 years; however, its mechanism of pharmacological action is not fully clear…”
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Syntrophy of Crypthecodinium cohnii and immobilized Zymomonas mobilis for docosahexaenoic acid production from sucrose-containing substrates by Strazdina, Inese, Klavins, Linards, Galinina, Nina, Shvirksts, Karlis, Grube, Mara, Stalidzans, Egils, Kalnenieks, Uldis

“…•Immobilized Z. mobilis converted sucrose to ethanol that was consumed by C. cohnii.•Levansucrase (sacB) and ndh-negative double mutant Zm6-ndh-sacB was…”
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Total optimization potential (TOP) approach based constrained design of isoprene and cis-abienol production in A. thaliana by Neiburga, Katrina D., Muiznieks, Reinis, Zake, Darta M., Pentjuss, Agris, Komasilovs, Vitalijs, Rohwer, Johann, Tissier, Alain, Stalidzans, Egils

“…Mathematical modelling is an important approach in metabolic engineering projects to support the design and adaptation of organisms for the needs of…”
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A hybrid strategy for growth-associated production of sophorolipid using a reconstructed genome-scale metabolic model for the fructophilic yeast Starmerella bombicola by Motamedian, Ehsan, Baumanis, Matiss Ricards, Daugavietis, Janis Edmunds, Berzina, Ieva, Shvirksts, Karlis, Dace, Elina, Liepins, Janis, Stalidzans, Egils

“…Metabolic modeling of Starmerella bombicola as a model yeast of the Wickerhamiella/Starmerella (W/S) clade is advantageous for studying the characteristics of…”
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