Search Results - "Egger, Martina"
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Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy
Published in Oncotarget (20-03-2015)“…Androgen deprivation therapy induces apoptosis or cell cycle arrest in prostate cancer (PCa) cells. Here we set out to analyze whether MCL1, a known mediator…”
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Journal Article -
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Enhanced inhibition of prostate tumor growth by dual targeting the androgen receptor and the regulatory subunit type iα of protein kinase a in vivo
Published in International journal of molecular sciences (04-06-2013)“…Progression to castration resistance is a major problem in the treatment of advanced prostate cancer and is likely to be driven by activation of several…”
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Journal Article -
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Lovastatin Causes Diminished PSA Secretion by Inhibiting AR Expression and Function in LNCaP Prostate Cancer Cells
Published in Urology (Ridgewood, N.J.) (01-06-2011)“…Objectives To investigate why statin users display a noticeable decline in prostate specific antigen (PSA) as revealed in recent clinical trials, we tested the…”
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Abstract 3: Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Abstract The cellular consequences of androgen deprivation therapy (ADT), a first-line therapy for locally advanced and metastatic prostate cancer (PCa), are…”
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Journal Article -
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Enhanced Inhibition of Prostate Tumor Growth by Dual Targeting the Androgen Receptor and the Regulatory Subunit Type I[alpha] of Protein Kinase A in Vivo
Published in International journal of molecular sciences (01-06-2013)“…Progression to castration resistance is a major problem in the treatment of advanced prostate cancer and is likely to be driven by activation of several…”
Get full text
Journal Article