Search Results - "Egeli, Unal"

Association between the apoptotic effect of Cabazitaxel and its pro-oxidant efficacy on the redox adaptation mechanisms in prostate cancer cells with different resistance phenotypes by Eryilmaz, Isil Ezgi, Egeli, Unal, Cecener, Gulsah

“…Redox adaptation causes poor prognosis by adapting cancer cells to excessive oxidative stress. Previously, we introduced an oxidative stress-resistant…”
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Talazoparib nanoparticles for overcoming multidrug resistance in triple‐negative breast cancer by Guney Eskiler, Gamze, Cecener, Gulsah, Egeli, Unal, Tunca, Berrin

“…Herein, we investigated efflux pumps‐mediated talazoparib‐resistance in the treatment of triple‐negative breast cancer (TNBC). Furthermore, we produced a novel…”
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An in vitro redox adaptation model for metastatic prostate cancer: Establishing, characterizing and Cabazitaxel response evaluating by Eryilmaz, Isil Ezgi, Egeli, Unal, Cecener, Gulsah

“…Little is known about the redox‐adapted cancer cells for understanding their pharmacologically targetable features and chemotherapeutic responses. Thus, we…”
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Synthetically Lethal BMN 673 (Talazoparib) Loaded Solid Lipid Nanoparticles for BRCA1 Mutant Triple Negative Breast Cancer by Guney Eskiler, Gamze, Cecener, Gulsah, Egeli, Unal, Tunca, Berrin

“…Purpose The purpose of the study was to produce BMN 673 loaded solid lipid nanoparticles (SLNs) to improve its therapeutic index, to minimize toxicity and to…”
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Triple negative breast cancer: new therapeutic approaches and BRCA status by Guney Eskiler, Gamze, Cecener, Gulsah, Egeli, Unal, Tunca, Berrin

“…Treatment of triple negative breast cancer (TNBC) is a clinically challenging problem due to intriguing clinical and pathologic features of TNBC and natural or…”
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Inhibitory Effects of Olea europaea Leaf Extract on Mesenchymal Transition Mechanism in Glioblastoma Cells by Mutlu, Melis, Tunca, Berrin, Ak Aksoy, Secil, Tekin, Cagla, Egeli, Unal, Cecener, Gulsah

“…Glioblastoma (GB) is the most aggressive form of brain tumor. Despite the current treatment methods, the survival rate of patients is very low. Therefore,…”
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The Anticancer Effect of Inula viscosa Methanol Extract by miRNAs' Re-regulation: An in vitro Study on Human Malignant Melanoma Cells by Colak, Dilara Kamer, Egeli, Unal, Eryilmaz, Isil Ezgi, Aybastier, Onder, Malyer, Hulusi, Cecener, Gulsah, Tunca, Berrin

“…Alternative and natural therapies are needed for malignant melanoma (MM), the most deadly skin cancer type due to chemotherapy's limited effect. In the present…”
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The regulatory effect of cabazitaxel on epithelial-mesenchymal transition in metastatic prostate cancer by Eryilmaz, Isil, Eskiler, Gamze, Egeli, Unal, Cecener, Gulsah

“…Introduction: Epithelial-mesenchymal transition (EMT) is a critical mechanism that promotes cancer cells to metastasis. Therefore, EMT regulation has become an…”
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The cytotoxic and antitumoral effects of Remdesivir, an antiviral RdRp inhibitor, on different cancer cells in vitro by Eryilmaz, Isil Ezgi, Bergel, Ceyda Colakoglu, Egeli, Unal, Cecener, Gulsah

“…Background Previous studies have shown similarities in the metabolism of cancer cells and parasites, suggesting that antiparasitic drugs may be used as…”
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Investigation of new treatment option for hepatocellular carcinoma: a combination of sorafenib with usnic acid by Yurdacan, Beste, Egeli, Unal, Guney Eskiler, Gamze, Eryilmaz, Isil Ezgi, Cecener, Gulsah, Tunca, Berrin

“…Objectives Sorafenib (SOR) is an orally administered molecular targeted agent in the systemic chemotherapy of hepatocellular carcinoma (HCC). However, the…”
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Association between the anticancer efficacy of cabazitaxel and toll-like receptor 4 mediating signaling pathways in metastatic castration-resistant prostate cancer cells by Guney Eskiler, Gamze, Ozkan, Asuman Deveci, Eryilmaz, Isil Ezgi, Egeli, Unal, Cecener, Gulsah

“…We evaluated the effect of cabazitaxel (CAB) as a third-line taxane on Toll-like receptor 4 (TLR4)-mediated signaling pathways, especially NF-κB activity, in…”
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In vitro cytotoxic and antiproliferative effects of usnic acid on hormone‐dependent breast and prostate cancer cells by Eryilmaz, Isil Ezgi, Guney Eskiler, Gamze, Egeli, Unal, Yurdacan, Beste, Cecener, Gulsah, Tunca, Berrin

“…The aim of the current study was first to investigate cytotoxic activity of usnic acid (UA) on hormone‐dependent breast and prostate cancer, and normal cells…”
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BMN 673 (talazoparib): A potent PARP inhibitor for triple negative breast cancer with different genetic profile by Guney Eskiler, Gamze, Cecener, Gulsah, Egeli, Unal, Tunca, Berrin

“…The objective of the present study was to elucidate the effect of BMN 673 (talozoparib) on BRCA1 mutant (HCC1937) and wild‐type (MDA‐MB‐231) triple negative…”
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Talazoparib Loaded Solid Lipid Nanoparticles: Preparation, Characterization and Evaluation of the Therapeutic Efficacy In vitro by Eskiler, Gamze Guney, Cecener, Gulsah, Dikmen, Gokhan, Egeli, Unal, Tunca, Berrin

“…In the present work, we report for the first time the therapeutic potential of talazoparib (BMN 673)-SLNs for the treatment of BRCA1 deficient Triple Negative…”
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Synergistic effects of hormone therapy drugs and usnic acid on hormone receptor‐positive breast and prostate cancer cells by Guney Eskiler, Gamze, Eryilmaz, Isil Ezgi, Yurdacan, Beste, Egeli, Unal, Cecener, Gulsah, Tunca, Berrin

“…The aim of this study was to investigate the combined effects of usnic acid (UA) and Tamoxifen (Tam) or Enzalutamide (Enz) on hormone receptor‐positive breast…”
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RNA‐based markers in biopsy cores with atypical small acinar proliferation: Predictive effect of T2E fusion positivity and MMP‐2 upregulation for a subsequent prostate cancer diagnosis by Eryilmaz, I. Ezgi, Aytac Vuruskan, Berna, Kaygısız, Onur, Egeli, Unal, Tunca, Berrin, Kordan, Yakup, Cecener, Gulsah

“…Background Atypical small acinar proliferation (ASAP) is a precursor lesion of prostate cancer (PC), and PC develops from this suspicious focus or an unsampled…”
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Investigation of VHL gene associated with miR-223 in clear cell renal cell carcinoma by Unal, Ufuk, Cecener, Gulsah, Tezcan Unlu, Havva, Aytac Vuruskan, Berna, Efendi Erdem, Ecem, Egeli, Unal, Ozturk Nazlioglu, Hulya, Kaygisiz, Onur, Tunca, Berrin, Vuruskan, Hakan

“…Background Clear cell type renal cell carcinoma (ccRCC) is the most common renal cell carcinoma (RCC). In this study, we examined the expressions of VHL and…”
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Contribution of functional dopamine D2 and D3 receptor variants to motor and non-motor symptoms of early onset Parkinson’s disease by Eryilmaz, Isil Ezgi, Erer, Sevda, Zarifoglu, Mehmet, Egeli, Unal, Karakus, Ece, Yurdacan, Beste, Cecener, Gulsah, Tunca, Berrin, Colakoglu, Beril, Bora Tokcaer, Ayse, Saka, Esen, Demirkiran, Meltem, Akbostanci, Cenk, Dogu, Okan, Kaleagasi, Hakan, Kenangil, Gulay, Cakmur, Raif, Elibol, Bulent

“…•The contribution of dopamine D2 and D3 receptor variants to motor and/or non-motor symptoms of EOPD was investigated.•All three SNPs were found to be…”
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Investigation of miR-146a expression profiles in fecal samples of patients with multiple sclerosis for early diagnosis and treatment by Unlu, Havva, Saridas, Furkan, Taskapilioglu, Ozlem, Cecener, Gulsah, Egeli, Unal, Turan, Omer, Tunca, Berrin, Zarifoglu, Mehmet

“…Introduction: Recent research into multiple sclerosis (MS) has focused on the role of microRNAs (miRNAs) in the development of the disease. This study was…”
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Long noncoding RNA MALAT1 may be a prognostic biomarker in IDH1/2 wild-type primary glioblastomas by Argadal, Omer Gokay, Mutlu, Melis, Ak Aksoy, Secil, Kocaeli, Hasan, Tunca, Berrin, Civan, Muhammet Nafi, Egeli, Unal, Cecener, Gulsah, Bekar, Ahmet, Taskapilioglu, Mevlut Ozgur, Tekin, Cagla, Tezcan, Gulcin, Tolunay, Sahsine

“…Primary glioblastoma (GB) is the most aggressive type of brain tumors. While mutations in isocitrate dehydrogenase (IDH) genes are frequent in secondary GBs…”
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