Search Results - "Ege, Markus J"

Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells by Schuijs, Martijn J., Willart, Monique A., Vergote, Karl, Gras, Delphine, Deswarte, Kim, Ege, Markus J., Madeira, Filipe Branco, Beyaert, Rudi, van Loo, Geert, Bracher, Franz, von Mutius, Erika, Chanez, Pascal, Lambrecht, Bart N., Hammad, Hamida

“…Growing up on a dairy farm protects children from allergy, hay fever, and asthma. A mechanism linking exposure to this endotoxin (bacterial…”
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Maturation of the gut microbiome during the first year of life contributes to the protective farm effect on childhood asthma by Depner, Martin, Taft, Diana Hazard, Kirjavainen, Pirkka V., Kalanetra, Karen M., Karvonen, Anne M., Peschel, Stefanie, Schmausser-Hechfellner, Elisabeth, Roduit, Caroline, Frei, Remo, Lauener, Roger, Divaret-Chauveau, Amandine, Dalphin, Jean-Charles, Riedler, Josef, Roponen, Marjut, Kabesch, Michael, Renz, Harald, Pekkanen, Juha, Farquharson, Freda M., Louis, Petra, Mills, David A., von Mutius, Erika, Ege, Markus J.

“…Growing up on a farm is associated with an asthma-protective effect, but the mechanisms underlying this effect are largely unknown. In the Protection against…”
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Bacterial microbiota of the upper respiratory tract and childhood asthma by Depner, Martin, PhD, Ege, Markus J., MD, Cox, Michael J., PhD, Dwyer, Sarah, PhD, Walker, Alan W., PhD, Birzele, Lena T, Genuneit, Jon, MD, Horak, Elisabeth, MD, Braun-Fahrländer, Charlotte, MD, Danielewicz, Hanna, MD, PhD, Maier, Raina M., PhD, Moffatt, Miriam F., PhD, Cookson, William O., MD, Heederik, Dick, PhD, von Mutius, Erika, MD, Legatzki, Antje, PhD

“…Background Patients with asthma and healthy controls differ in bacterial colonization of the respiratory tract. The upper airways have been shown to reflect…”
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microRNA in native and processed cow's milk and its implication for the farm milk effect on asthma by Kirchner, Benedikt, MSc, Pfaffl, Michael W., PhD, Dumpler, Joseph, Dipl-Ing, von Mutius, Erika, MD, Ege, Markus J., MD

“…Because of the strong analogy between human and bovine miRNAs, the presence of these molecules in raw milk and particularly the fat fraction might be…”
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Allergic rhinitis as a predictor for wheezing onset in school-aged children by Rochat, Mascha K., MD, Illi, Sabina, PhD, Ege, Markus J., MD, Lau, Susanne, MD, Keil, Thomas, MD, MSc, Wahn, Ulrich, MD, von Mutius, Erika, MD

“…Background Rhinitis in older children and adults has been shown to be a predictor for adolescent- and adult-onset asthma. These findings suggest an interaction…”
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Consumption of unprocessed cow's milk protects infants from common respiratory infections by Loss, Georg, PhD, Depner, Martin, PhD, Ulfman, Laurien H., PhD, van Neerven, R.J. Joost, PhD, Hose, Alexander J., MPH, Genuneit, Jon, MD, Karvonen, Anne M., PhD, Hyvärinen, Anne, PhD, Kaulek, Vincent, PhD, Roduit, Caroline, MD, Weber, Juliane, MD, Lauener, Roger, MD, Pfefferle, Petra Ina, PhD, DrPH, Pekkanen, Juha, MD, PhD, Vaarala, Outi, MD, PhD, Dalphin, Jean-Charles, MD, PhD, Riedler, Josef, MD, Braun-Fahrländer, Charlotte, MD, von Mutius, Erika, MD, Ege, Markus J., MD

“…Background Breast-feeding is protective against respiratory infections in early life. Given the co-evolutionary adaptations of humans and cattle, bovine milk…”
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The Hygiene Hypothesis in the Age of the Microbiome by Ege, Markus J

“…The original version of the hygiene hypothesis suggested that infections transmitted early in life by "unhygienic contact" prevented allergies. Examples were…”
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Gene-environment interaction for childhood asthma and exposure to farming in Central Europe by Ege, Markus J., MD, Strachan, David P., MD, Cookson, William O.C.M., MD, DPhil, Moffatt, Miriam F., MD, DPhil, Gut, Ivo, PhD, Lathrop, Mark, PhD, Kabesch, Michael, MD, Genuneit, Jon, MD, Büchele, Gisela, PhD, Sozanska, Barbara, MD, Boznanski, Andrzej, MD, PhD, Cullinan, Paul, MD, Horak, Elisabeth, MD, Bieli, Christian, MD, Braun-Fahrländer, Charlotte, MD, Heederik, Dick, PhD, von Mutius, Erika, MD

“…Background Asthma is a disease in which both genetic and environmental factors play important roles. The farming environment has consistently been associated…”
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Atopic sensitization in the first year of life by Depner, Martin, PhD, Ege, Markus J., MD, Genuneit, Jon, MD, Pekkanen, Juha, MD, PhD, Roponen, Marjut, PhD, Hirvonen, Maija-Riitta, PhD, Dalphin, Jean-Charles, MD, PhD, Kaulek, Vincent, PhD, Krauss-Etschmann, Susanne, MD, Riedler, Josef, MD, Braun-Fahrländer, Charlotte, MD, Roduit, Caroline, MD, MPH, Lauener, Roger, MD, Pfefferle, Petra I., PhD, DPH, Weber, Juliane, MD, von Mutius, Erika, MD

“…Background There is conflicting evidence on whether allergen-specific memory is primed prenatally, whether this priming affects persistent immunologic effects,…”
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Excessive Unbalanced Meat Consumption in the First Year of Life Increases Asthma Risk in the PASTURE and LUKAS2 Birth Cohorts by Hose, Alexander J, Pagani, Giulia, Karvonen, Anne M, Kirjavainen, Pirkka V, Roduit, Caroline, Genuneit, Jon, Schmaußer-Hechfellner, Elisabeth, Depner, Martin, Frei, Remo, Lauener, Roger, Riedler, Josef, Schaub, Bianca, Fuchs, Oliver, von Mutius, Erika, Divaret-Chauveau, Amandine, Pekkanen, Juha, Ege, Markus J

“…A higher diversity of food items introduced in the first year of life has been inversely related to subsequent development of asthma. In the current analysis,…”
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Atopy: A mirror of environmental changes? by Ege, Markus J., MD, MPH, von Mutius, Erika, MD, MSc

“…The specificity of this effect renders a systematic bias extremely unlikely. [...]the discrepancy between rural and urban populations is informative in itself…”
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Structural racism and readmission for childhood asthma—a quest for causality by Ege, Markus J.

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CURRENT CONCEPTS: The Asthma Epidemic by Eder, Waltraud, Ege, Markus J, Erika von Mutius

“…There is widespread concern that the prevalence of asthma is still rising in developed countries, but the economic and humanitarian effects of asthma are…”
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The Asthma Epidemic by Eder, Waltraud, Ege, Markus J, von Mutius, Erika

“…This review surveys the data on the increase in the prevalence of asthma in recent decades and finds evidence of a plateau in many Western countries. The…”
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Prenatal Markers of Asthma and Maternal Asthma Status by Ege, Markus J

“…In the present analysis, they focused on Th1 versus Th2 cytokine ratios produced by maternal peripheral blood mononuclear cells during the last trimester of…”
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Asthma and Prenatal Inflammation by Ege, Markus J

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Exposure to Environmental Microorganisms and Childhood Asthma by Ege, Markus J, Mayer, Melanie, Normand, Anne-Cécile, Genuneit, Jon, Cookson, William O.C.M, Braun-Fahrländer, Charlotte, Heederik, Dick, Piarroux, Renaud, von Mutius, Erika

“…Growing up on a farm protects children from asthma. In this study, the investigators show that the diversity of microbial exposure of farm children as compared…”
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Allergic Disease and Atopic Sensitization in Children in Relation to Measles Vaccination and Measles Infection by Rosenlund, Helen, Bergstrom, Anna, Alm, Johan S, Swartz, Jackie, Scheynius, Annika, van Hage, Marianne, Johansen, Kari, Brunekreef, Bert, von Mutius, Erika, Ege, Markus J, Riedler, Josef, Braun-Fahrlander, Charlotte, Waser, Marco, Pershagen, Goran, and PARSIFAL Study Group

“…Our aim was to investigate the role of measles vaccination and measles infection in the development of allergic disease and atopic sensitization. A total of 14…”
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Asthma and the hygiene hypothesis. Does cleanliness matter? by Weber, Juliane, Illi, Sabina, Nowak, Dennis, Schierl, Rudolf, Holst, Otto, von Mutius, Erika, Ege, Markus J

“…The early hygiene hypothesis explained the development of allergies by a lack of infections; nowadays, the aspect of excessive cleanliness in affluent…”
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Clinical and epidemiologic phenotypes of childhood asthma by Depner, Martin, Fuchs, Oliver, Genuneit, Jon, Karvonen, Anne M, Hyvärinen, Anne, Kaulek, Vincent, Roduit, Caroline, Weber, Juliane, Schaub, Bianca, Lauener, Roger, Kabesch, Michael, Pfefferle, Petra Ina, Frey, Urs, Pekkanen, Juha, Dalphin, Jean-Charles, Riedler, Josef, Braun-Fahrländer, Charlotte, von Mutius, Erika, Ege, Markus J

“…Clinical and epidemiologic approaches have identified two distinct sets of classifications for asthma and wheeze phenotypes. To compare epidemiologic phenotype…”
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