Search Results - "Egawa, Yuya"
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1
Colorimetric Sugar Sensing Using Boronic Acid-Substituted Azobenzenes
Published in Materials (14-02-2014)“…In association with increasing diabetes prevalence, it is desirable to develop new glucose sensing systems with low cost, ease of use, high stability and good…”
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2
Multinuclear NMR Study on the Formation and Polyol-Induced Deformation Mechanisms of Wormlike Micelles Composed of Cetyltrimethylammonium Bromide and 3‑Fluorophenylboronic Acid
Published in Langmuir (23-03-2021)“…We had previously confirmed a glucose-responsive decrease in the viscosity of cetyltrimethylammonium bromide (CTAB) and phenylboronic acid (PBA) wormlike…”
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3
A New Boron-Rhodamine-Containing Carboxylic Acid as a Sugar Chemosensor
Published in Sensors (Basel, Switzerland) (30-01-2023)“…We propose a boron-rhodamine-containing carboxylic acid (BRhoC) substance as a new sugar chemosensor. BRhoC was obtained by the Friedel-Crafts reaction of…”
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4
pH-Induced Interconversion between J-Aggregates and H-Aggregates of 5,10,15,20-Tetrakis(4-sulfonatophenyl)porphyrin in Polyelectrolyte Multilayer Films
Published in Langmuir (18-12-2007)“…We fabricated a layer-by-layer (LbL) film composed of 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrin (TPPS) and poly(allylamine) (PAA) and investigated its pH…”
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Caco-2 Cell Sheet Partially Laminated with HT29-MTX Cells as a Novel In Vitro Model of Gut Epithelium Drug Permeability
Published in Pharmaceutics (01-09-2023)“…The intestinal epithelial Caco-2 cell monolayer is a well-established in vitro model useful for predicting intestinal drug absorption in humans. Coculture…”
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Sugar-Responsive Layer-by-Layer Film Composed of Phenylboronic Acid-Appended Insulin and Poly(vinyl alcohol)
Published in Chemical & pharmaceutical bulletin (2018)“…Previous studies have shown that reversible chemical bond formation between phenylboronic acid (PBA) and 1,3-diol can be utilized as the driving force for the…”
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7
Glucose Responsive Rheological Change and Drug Release from a Novel Worm-like Micelle Gel Formed in Cetyltrimethylammonium Bromide/Phenylboronic Acid/Water System
Published in Molecular pharmaceutics (05-03-2018)“…A novel glucose (Glc)-responsive gel formed by worm-like micelles (WLMs) has the potential to provide a self-regulating insulin delivery system. We have…”
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8
Rotaxa-polymeric-gelation of acrylamides with vinyl-β-cyclodextrin
Published in Journal of inclusion phenomena and macrocyclic chemistry (01-10-2020)“…Previously, we have reported a single-step preparation method for a topological gel by copolymerizing isoprene and vinyl-modified β-cyclodextrin (V-β-CyD). In…”
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9
Sugar-Responsive Layer-by-Layer Film Composed of Phenylboronic Acid-Appended Insulin and Poly (vinyl alcohol)
Published in Chemical and Pharmaceutical Bulletin (01-04-2018)“…Previous studies have shown that reversible chemical bond formation between phenylboronic acid (PBA) and 1,3-diol can be utilized as the driving force for the…”
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10
Sugar-responsive smart materials based on phenylboronic acid and cyclodextrin
Published in Journal of inclusion phenomena and macrocyclic chemistry (15-06-2019)“…This review focuses on sugar-responsive materials based on phenylboronic acid (PBA) as a sugar-sensing motif and cyclodextrins (CyDs) as a basic skeleton of…”
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11
Investigation of factors that cause insulin precipitation and/or amyloid formation in insulin formulations
Published in Journal of pharmaceutical health care and sciences (30-10-2019)“…Multiple daily subcutaneous injections (MDSIs) are mainly used for formulating an insulin therapy for diabetic patients; however, they also cause…”
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12
The Use of an Artificial Skin Model to Study Transdermal Absorption of Drugs in Inflamed Skin
Published in Biological & pharmaceutical bulletin (01-02-2012)“…Studies on drug disposition in inflamed skin are important for safe and effective application of topical drugs. Here, the absorption of flurbiprofen (FP)…”
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13
Sugar response of layer-by-layer films composed of poly(vinyl alcohol) and poly(amidoamine) dendrimer bearing 4-carboxyphenylboronic acid
Published in Colloid and polymer science (01-04-2015)“…Multilayered thin films composed of poly(vinyl alcohol) (PVA) and 4-carboxyphenylboronic acid-modified poly(amidoamine) dendrimer (4-PBA-PAMAM) were prepared…”
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14
Effect of Physiological Changes in the Skin on Systemic Absorption of Tacrolimus Following Topical Application in Rats
Published in Biological & pharmaceutical bulletin (01-03-2016)“…Tacrolimus (TL) ointment is a topical treatment for atopic dermatitis, a disease that exhibits various skin conditions. The effect of skin pathologies on the…”
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15
Cell Adhesive Character of Phenylboronic Acid-Modified Insulin and Its Potential as Long-Acting Insulin
Published in Pharmaceuticals (Basel, Switzerland) (19-08-2019)“…Phenylboronic acid (PBA) derivatives have attracted substantial attention owing to their unique character of forming dynamic covalent bonds with polyol…”
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Evaluation of the Effects of Absorption Enhancers on Caco-2 Cell Monolayers by Using a Pore Permeation Model Involving Two Different Sizes
Published in Biological & pharmaceutical bulletin (01-11-2013)“…We applied a parallel pore permeation model based on the Renkin molecular sieving function by using two different-sized pathways to analyze the…”
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Sugar-Sensitive Supramolecular Structures Based on Phenylboronic Acid-Modified Cyclodextrins
Published in Chemical & pharmaceutical bulletin (01-11-2013)“…Supramolecular structures were developed from phenylboronic acid-modified cyclodextrins (PBA-CyDs). The intermolecular interaction between the PBA moiety and…”
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Supramolecular Nanomachines for Sugar Responsive Insulin Release Systems
Published in YAKUGAKU ZASSHI (2013)“…Cyclodextrins (CyDs) are cyclic oligosaccharides composed of 6, 7, or 8 glucopyranoside units, named α-, β-, or γ-CD, respectively. CyDs consist of a…”
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19
Performance evaluation of single stage diaphragmless vertical gas gun for nitrogen and helium gas propellants
Published in Mechanical Engineering Journal (01-01-2016)“…The main difficulty in conducting a high velocity experiment with a projectile accelerator is predicting the projectile velocity with great accuracy. This is…”
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Fluorometric determination of inulin using 5-quinolineboronic acid and inulinase
Published in Analytical biochemistry (01-07-2012)“…Inulin is a polysaccharide composed mainly of d-fructose units and is the most reliable indicator of the glomerular filtration rate. We have proposed an inulin…”
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