Search Results - "Egan, Martin"

Peroxisomes move by hitchhiking on early endosomes using the novel linker protein PxdA by Salogiannis, John, Egan, Martin J, Reck-Peterson, Samara L

“…Eukaryotic cells use microtubule-based intracellular transport for the delivery of many subcellular cargos, including organelles. The canonical view of…”
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Lis1 is an initiation factor for dynein-driven organelle transport by Egan, Martin J, Tan, Kaeling, Reck-Peterson, Samara L

“…The molecular motor cytoplasmic dynein is responsible for most minus-end-directed, microtubule-based transport in eukaryotic cells. It is especially important…”
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Discovery of novel intermediate forms redefines the fungal tree of life by Jones, Meredith D. M., Forn, Irene, Gadelha, Catarina, Egan, Martin J., Bass, David, Massana, Ramon, Richards, Thomas A.

“…Pond-dwelling naked fungi Our current understanding of fungal diversity is coloured by the forms that can be grown in culture — filamentous or yeast-like forms…”
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Septum-associated microtubule organizing centers within conidia support infectious development by the blast fungus Magnaporthe oryzae by Rogers, Audra Mae, Egan, Martin John

“…•This study provides improved insight into the subcellular cytoskeletal organization of the M. oryzae conidium and appressorium, with implications for the…”
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Aspergillus SUMOylation mutants exhibit chromosome segregation defects including chromatin bridges by Zhang, Jun, Qiu, Rongde, Bieger, Baronger D, Oakley, C Elizabeth, Oakley, Berl R, Egan, Martin J, Xiang, Xin

“…Abstract Functions of protein SUMOylation remain incompletely understood in different cell types. Via forward genetics, here we identified ubaBQ247*, a…”
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Microtubule-based transport in filamentous fungi by Egan, Martin J, McClintock, Mark A, Reck-Peterson, Samara L

“…Highlights ► Dynein-driven and kinesin-driven microtubule-based transport is linked to neuropathology. ► Filamentous fungi are valuable models to study…”
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Generation of reactive oxygen species by fungal NADPH oxidases is required for rice blast disease by Egan, Martin J, Wang, Zheng-Yi, Jones, Mark A, Smirnoff, Nicholas, Talbot, Nicholas J

“…One of the first responses of plants to microbial attack is the production of extracellular superoxide surrounding infection sites. Here, we report that…”
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The spindle pole-body localization of activated cytoplasmic dynein is cell cycle-dependent in Aspergillus nidulans by Bieger, Baronger Dowell, Osmani, Aysha H., Xiang, Xin, Egan, Martin J.

“…•The SPB localization of activated dynein is cell cycle-dependent.•The SPB signals of activated dynein are observed during G1.•The SPB signals of activated…”
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Autophagic Fungal Cell Death Is Necessary for Infection by the Rice Blast Fungus by Veneault-Fourrey, Claire, Barooah, Madhumita, Egan, Martin, Wakley, Gavin, Talbot, Nicholas J

“…Rice blast is caused by the fungus Magnaporthe grisea, which elaborates specialized infection cells called appressoria to penetrate the tough outer cuticle of…”
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Crowdsourced analysis of fungal growth and branching on microfluidic platforms by Hopke, Alex, Mela, Alex, Ellett, Felix, Carter-House, Derreck, Peña, Jesús F, Stajich, Jason E, Altamirano, Sophie, Lovett, Brian, Egan, Martin, Kale, Shiv, Kronholm, Ilkka, Guerette, Paul, Szewczyk, Edyta, McCluskey, Kevin, Breslauer, David, Shah, Hiral, Coad, Bryan R, Momany, Michelle, Irimia, Daniel

“…Fungal hyphal growth and branching are essential traits that allow fungi to spread and proliferate in many environments. This sustained growth is essential for…”
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Cytoplasmic dynein is required for the spatial organization of protein aggregates in filamentous fungi by Egan, Martin J., McClintock, Mark A., Hollyer, Ian H.L., Elliott, Hunter L., Reck-Peterson, Samara L.

“…Eukaryotes have evolved multiple strategies for maintaining cellular protein homeostasis. One such mechanism involves neutralization of deleterious protein…”
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A microscopy-based screen employing multiplex genome sequencing identifies cargo-specific requirements for dynein velocity by Tan, Kaeling, Roberts, Anthony J, Chonofsky, Mark, Egan, Martin J, Reck-Peterson, Samara L

“…The timely delivery of membranous organelles and macromolecules to specific locations within the majority of eukaryotic cells depends on microtubule-based…”
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Long‐distance early endosome motility in Aspergillus fumigatus promotes normal hyphal growth behaviors in controlled microenvironments but is dispensable for virulence by Bieger, Baronger Dowell, Rogers, Audra Mae, Bates, Steven, Egan, Martin John

“…In filamentous fungi, early endosomes are continuously trafficked to, and from, the growing hyphal tip by microtubule‐based motor proteins, serving as…”
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Genomes, free radicals and plant cell invasion: recent developments in plant pathogenic fungi by Egan, Martin J, Talbot, Nicholas J

“…This review describes current advances in our understanding of fungal–plant interactions. The widespread application of whole genome sequencing to a diverse…”
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Autophagy machinery promotes the chaperone-mediated formation and compartmentalization of protein aggregates during appressorium development by the rice blast fungus by Rogers, Audra Mae, Egan, Martin John

“…The chaperone-mediated sequestration of misfolded proteins into specialized quality control compartments represents an important strategy for maintaining…”
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The cell-end protein Tea4 spatially regulates hyphal branch initiation and appressorium remodeling in the blast fungus Magnaporthe oryzae by Rogers, Audra Mae, Taylor, Rachel, Egan, Martin John

“…The differentiation of specialized infection cells, called appressoria, from polarized germ tubes of the blast fungus , requires remarkable remodeling of cell…”
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4D Widefield Fluorescence Imaging of Appressorium Morphogenesis by Magnaporthe oryzae by Rogers, Audra, Dulal, Nawaraj, Egan, Martin

“…Fluorescence microscopy has become a widely used and indispensable tool for the M. oryzae research community, providing unique insight into appressorium…”
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Dynamic assembly of a higher-order septin structure during appressorium morphogenesis by the rice blast fungus by Dulal, Nawaraj, Rogers, Audra, Wang, Yong, Egan, Martin

“…•Quantitative 4D fluorescence imaging of appressorium morphogenesis by M. oryzae reveals the spatiotemporal dynamics of a higher-order septin ring…”
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Turgor-dependent and coronin-mediated F-actin dynamics drive septin disc-to-ring remodeling in the blast fungus Magnaporthe oryzae by Dulal, Nawaraj, Rogers, Audra Mae, Proko, Rinalda, Bieger, Baronger Dowell, Liyanage, Rohana, Krishnamurthi, Venkata Rao, Wang, Yong, Egan, Martin John

“…The fungus uses a specialized pressure-generating infection cell called an appressorium to break into rice leaves and initiate disease. Appressorium…”
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Dissecting the Cellular Control of Septin Organization in a Global Cereal Killer by Proko, Rinalda, Dulal, Nawaraj, Liyanage, Rohana, Egan, Martin

“…Abstract only Rice blast disease, caused by the fungus Magnaporthe oryzae , destroys enough rice each year to feed 60 million people, and is a major threat to…”
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