Search Results - "Egan, E A"
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Component-specific surface and physiological activity in bovine-derived lung surfactants
Published in Chemistry and physics of lipids (2002)“…Composition, surface activity and effects on pressure–volume ( P– V) mechanics are examined for lavaged calf lung surfactant (LS) and the clinical exogenous…”
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High-Versus Low-Threshold Surfactant Retreatment For Neonatal Respiratory Distress Syndrome
Published in Pediatrics (Evanston) (01-08-2000)“…Surfactant therapy has become an effective standard therapy for infants with respiratory distress syndrome (RDS). The first dose may be given either as…”
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Pulmonary hemodynamics in fetal lambs during development at normal and increased oxygen tension
Published in Journal of applied physiology (1985) (01-07-1992)“…During the latter third of gestation, the number of resistance vessels in the lungs of the fetal sheep increases by 10-fold even after correction for lung…”
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Double-blind clinical trial of calf lung surfactant extract for the prevention of hyaline membrane disease in extremely premature infants
Published in Pediatrics (Evanston) (01-10-1985)“…A prospective, double-blind, controlled trial was conducted to determine whether instillation of an exogenous surfactant into the lungs before the first breath…”
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Content of dipalmitoyl phosphatidylcholine in lung surfactant : Ramifications for surface activity
Published in Pediatric research (01-05-1996)“…The content of dipalmitoyl phophatidylcholine (DPPC) in the phosphatidylcholine (PC) fraction of calf lung surfactant extract (CLSE) is measured by gas…”
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Lung surfactant replacement in premature lambs with extracted lipids from bovine lung lavage: effects of dose, dispersion technique, and gestational age
Published in Pediatric research (01-06-1985)“…Extracted bovine calf lung lipids (CLL) with minimal protein (approximately 1%) were instilled prior to ventilation in groups of premature lambs of average…”
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Development of pulmonary vascular response to oxygen
Published in The American journal of physiology (01-03-1988)“…The ability of the pulmonary circulation of the fetal lamb to respond to a rise in oxygen tension was studied from 94 to 146 days of gestation. The…”
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Lung inflation, lung solute permeability, and alveolar edema
Published in Journal of applied physiology: respiratory, environmental and exercise physiology (01-07-1982)“…A series of experiments in anesthetized rabbits were conducted to determine whether hyperinflation of the lung alone could produce a protein-permeable lung…”
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Pathophysiology of congenital diaphragmatic hernia. III: Exogenous surfactant therapy for the high-risk neonate with CDH
Published in Journal of pediatric surgery (01-07-1992)“…Exogenous surfactant therapy (EST) in surfactant-deficient premature infants has been shown to improve lung compliance, decrease morbidity, and improve…”
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Surfactant decreases pulmonary vascular resistance and increases pulmonary blood flow in the fetal lamb model of congenital diaphragmatic hernia
Published in Journal of pediatric surgery (01-04-1996)“…Introduction: Experiments using animal models of neonatal respiratory distress syndrome have shown a decrease in pulmonary vascular resistance (PVR) with…”
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Response of alveolar epithelial solute permeability to changes in lung inflation
Published in Journal of applied physiology: respiratory, environmental and exercise physiology (01-12-1980)“…The relation between the solute permeability of th alveolar epithelium, characterized as a pore radius, and lung inflation was studied in anesthetized dogs…”
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Reduced blood levels of reelin as a vulnerability factor in pathophysiology of autistic disorder
Published in Cellular and molecular neurobiology (01-04-2002)“…1. Autism is a severe neurodevelopmental disorder with potential genetic and environmental etiologies. Recent genetic linkage reports and biochemical analysis…”
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Synthetic surfactants in infants with respiratory distress syndrome
Published in The New England journal of medicine (18-06-1992)Get full text
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Interstitial fluid volumes and albumin spaces in pulmonary oxygen toxicity
Published in Journal of applied physiology: respiratory, environmental and exercise physiology (01-12-1984)“…In rabbits exposed to 100% O2 at 1 ATA from 48 to 72 h, we measured the accumulation of intravenously injected 125I-bovine albumin, [57Co]cyanocobalamin, and…”
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Natural and artificial lung surfactant replacement therapy in premature lambs
Published in Journal of applied physiology: respiratory, environmental and exercise physiology (01-09-1983)“…The effect of tracheal instillation of surface-active mixtures in premature lambs was studied as an animal model of exogenous surfactant replacement therapy…”
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Instillation of calf lung surfactant extract (calfactant) is beneficial in pediatric acute hypoxemic respiratory failure
Published in Critical care medicine (01-01-1999)“…OBJECTIVEProspective study of the efficacy of calf lung surfactant extract in pediatric respiratory failure. DESIGNMulti-institutional, prospective,…”
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Impact of lung surfactant therapy on chronic lung diseases in premature infants
Published in Clinics in perinatology (01-09-1992)“…Bronchopulmonary dysplasia (BPD) and chronic lung disease remain common complications of prematurity. This article addresses the evolution of BPD since its…”
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Effects of 100% O2 breathing on permeability of alveolar epithelium to solute
Published in Journal of applied physiology: respiratory, environmental and exercise physiology (01-04-1981)“…We measured the effects of 100% O2 exposure at 1 atm for 48 (n = 5) and 63 h (n = 6) on the solute permeability of the alveolar epithelium of rabbits. We…”
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Reduced incidence of hyaline membrane disease in extremely premature infants following delay of delivery in mother with preterm labor: use of ritodrine and betamethasone
Published in Pediatrics (Evanston) (01-11-1986)“…Data from two groups of infants (24 to 28 weeks' gestational age) excluded from a controlled trial of the use of calf lung surfactant extract for the…”
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