Search Results - "Efstathiou, J A"

Proton beam therapy and localised prostate cancer: current status and controversies by Efstathiou, J A, Gray, P J, Zietman, A L

“…Proton therapy is a promising, but costly, treatment for prostate cancer. Theoretical physical advantages exist; yet to date, it has been shown only to be…”
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Hypermethylation of the promoter region of the E-cadherin gene (CDH1) in sporadic and ulcerative colitis associated colorectal cancer by Wheeler, J M D, Kim, H C, Efstathiou, J A, Ilyas, M, Mortensen, N J McC, Bodmer, W F

“…BACKGROUND Ulcerative colitis associated colorectal cancer (UCACRC) has several distinctive clinicopathological and genetic features which differ from sporadic…”
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Intestinal Trefoil Factor Controls the Expression of the Adenomatous Polyposis Coli--Catenin and the E-Cadherin--Catenin Complexes in Human Colon Carcinoma Cells by Efstathiou, J. A., Noda, M., Rowan, A., Dixon, C., Chinery, R., Jawhari, A., Hattori, T., Wright, N. A., Bodmer, W. F., Pignatelli, M.

“…Intestinal trefoil factor 3 (TFF3) is a member of the trefoil family of peptides, small molecules constitutively expressed in epithelial tissues, including the…”
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Will the Use of Biomarkers Improve Bladder Cancer Radiotherapy Delivery? by Solanki, A.A., Venkatesulu, B.P., Efstathiou, J.A.

“…Advances in the field of cancer biology and molecular techniques have led to a better understanding of the molecular underpinnings driving cancer development…”
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Validation of a deformable image registration technique for cone beam CT‐based dose verification by Moteabbed, M., Sharp, G. C., Wang, Y., Trofimov, A., Efstathiou, J. A., Lu, H.‐M.

“…Purpose: As radiation therapy evolves toward more adaptive techniques, image guidance plays an increasingly important role, not only in patient setup but also…”
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Proton therapy of prostate cancer by anterior-oblique beams: implications of setup and anatomy variations by Moteabbed, M, Trofimov, A, Sharp, G C, Wang, Y, Zietman, A L, Efstathiou, J A, Lu, H-M

“…Proton therapy of prostate by anterior beams could offer an attractive option for treating patients with hip prosthesis and limiting the high-dose exposure to…”
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Mutated Epithelial Cadherin Is Associated with Increased Tumorigenicity and Loss of Adhesion and of Responsiveness to the Motogenic Trefoil Factor 2 in Colon Carcinoma Cells by Efstathiou, J. A., Liu, D., Wheeler, J. M. D., Kim, H. C., Beck, N. E., Ilyas, M., Karayiannakis, A. J., N. J. Mc C. Mortensen, Kmiot, W., Playford, R. J., Pignatelli, M., Bodmer, W. F.

“…Epithelial (E)-cadherin and its associated cytoplasmic proteins (α -, β -, and γ -catenins) are important mediators of epithelial cell-cell adhesion and…”
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Impact of perioperative chemotherapy on survival in patients with advanced primary urethral cancer: results of the international collaboration on primary urethral carcinoma by Gakis, G., Morgan, T.M., Daneshmand, S., Keegan, K.A., Todenhöfer, T., Mischinger, J., Schubert, T., Zaid, H.B., Hrbacek, J., Ali-El-Dein, B., Clayman, R.H., Galland, S., Olugbade, K., Rink, M., Fritsche, H.-M., Burger, M., Chang, S.S., Babjuk, M., Thalmann, G.N., Stenzl, A., Efstathiou, J.A.

“…To investigate the impact of perioperative chemo(radio)therapy in advanced primary urethral carcinoma (PUC). A series of 124 patients (86 men, 38 women) were…”
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Modulation of Epithelial Cell Adhesion in Gastrointestinal Homeostasis by Efstathiou, Jason Alexander, Pignatelli, Massimo

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SU‐E‐T‐659: Maximizing the Therapeutic Effect of a Fractionated Treatment with Delivery of Inhomogeneous Daily Dose Distributions by Trofimov, A, Niemierko, A, Efstathiou, JA

“…Purpose: To evaluate potential gain in therapeutic effect from delivery of daily inhomogeneous fractional dose distributions in proton therapy, using pencil…”
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Gastrin receptor expression and function during rapid transformation of the enterochromaffin-like cells in an African rodent by Tang, Laura H, Luque, Eileen A, Efstathiou, Jason A, Bortecen, Kerem H, Kidd, Mark, Tarasova, Nadya I, Modlin, Irvin M

“…The enterochromaffin-like cell (ECL) cells of the stomach are principally regulated by gastrin via a gastrin/CCK B receptor (G R) which modulates both…”
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Gastrin-Regulated Expression of p53 in Transformed Enterochromaffin-like Cells in the African Rodent Mastomys by Luque, Eileen A, Tang, Laura H, Bortecen, Kerem H, Kidd, Mark, Miu, Kun, Efstathiou, Jason A, Modlin, Irvin M

“…The tumor suppressor p53 functions at the G1/S-phase checkpoint of the cell cycle to direct cells that have accumulated somatic mutations toward apoptosis and…”
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Impact of the COVID-19 Pandemic on Prostate Cancer Radiotherapy Practice Patterns: A Northeast Regional Longitudinal Survey Study by Kamran, S.C., Aldrighetti, C., Oladeru, O.T., Niemierko, A., Zietman, A.L., Efstathiou, J.A.

“…During the COVID-19 pandemic, the National Comprehensive Cancer Network (NCCN) provided management guidelines for prostate cancer (PCa) patients undergoing…”
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Qualitative and Quantitative Analysis of a Deep Learning Auto Contouring Model for Radiotherapy in Localized Prostate Cancer by Boyd, G.H., Efstathiou, J.A., Kamran, S.C., Zietman, A.L., Miyamoto, D.T., Kirk, M.C., Wang, Y.

“…To evaluate a convolutional neural network auto-contouring (AC) model created for treatment planning in patients receiving radiotherapy for localized prostate…”
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Impact of AR-V7 and Other Androgen Receptor Splice Variant Expression on Outcomes of Post-Prostatectomy Salvage Therapy by Konieczkowski, D.J., Otani, K., Drumm, M.R., Wu, S., Saylor, P.J., Wu, C.L., Efstathiou, J.A., Miyamoto, D.T.

“…Radiotherapy (RT) with or without androgen deprivation therapy (ADT) plays a key role in the salvage treatment of prostate cancer recurrent after…”
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Transforming Growth Factor β Stimulation of Colorectal Cancer Cell Lines: Type II Receptor Bypass and Changes in Adhesion Molecule Expression by Ilyas, Mohammad, Efstathiou, Jason A., Straub, Josef, Kim, Hee C., Bodmer, Walter F.

“…The type II transforming growth factor (TGF)-β receptor gene (TGFBR2) is often mutated in nucleotide repeat sequences in colorectal cancers that are…”
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NRG Oncology/RTOG 0926: Phase II Protocol for Patients With Stage T1 Bladder Cancer to Evaluate Selective Bladder Preserving Treatment by Radiation Therapy Concurrent With Radiosensitizing Chemotherapy Following a Thorough Transurethral Surgical Re-Staging by Dahl, D.M., Rodgers, J., Shipley, W.U., Michaelson, D., Wu, C.L., Parker, W., Efstathiou, J.A., Jani, A., Cury, F., Hudes, R., Michalski, J.M., Hartford, A.C., Song, D., Citrin, D.E., Karrison, T.G., Feng, F.Y.

“…Recurrent T1 bladder cancer has a substantial rate of progression and is usually treated with radical cystectomy. Bladder preservation therapy is a…”
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Re: Active Surveillance of Prostate Cancer is a Viable Option for Men Younger than 60 Years by Shah, Navin, Ioffe, Vladimir

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Reply by Authors by Salari, K., Kuppermann, D., Preston, M. A., Dahl, D. M., Barrisford, G. W., Efstathiou, J. A., Blute, M. L., Vesprini, D., Loblaw, A., Zietman, A. L., Klotz, L., Feldman, A. S.

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Validation of a 22-gene Genomic Classifier in the NRG Oncology/RTOG 9202, 9413 and 9902 Phase III Randomized Trials: A Biopsy-Based Individual Patient Meta-Analysis in High-Risk Prostate Cancer by Nguyen, P.L., Huang, H.C., Davicioni, E., Sandler, H.M., Shipley, W.U., Efstathiou, J.A., Simko, J., Pollack, A., Dicker, A.P., Roach, M., Rosenthal, S.A., Morginstin, M., Mendez, L., Hartford, A.C., Hall, W.A., Desai, A.B., Rabinovitch, R., Peters, C.A., Rodgers, J., Feng, F.Y.

“…Decipher is a prognostic 22-gene genomic classifier (GC) prospectively validated post-prostatectomy. Herein, we validate the performance of the GC in…”
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