Search Results - "Efrati, Edna"

Decreased Systemic Busulfan Exposure After Oral Dosing With Concomitant Levetiracetam Compared With Phenytoin by Artul, Tareq, Henig, Israel, Nassar, Laila, Yehudai-Ofir, Dana, Scherb, Inna, Lurie, Yael, Efrati, Edna, Zuckerman, Tsila, Kurnik, Daniel

“…Busulfan (Bu) conditioning used in hematopoietic stem cell transplantation may induce seizures, and prophylactic antiepileptic treatment is recommended…”
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Effective elimination of high-dose methotrexate by repeated hemodiafiltration and high-flux hemodialysis in patients with acute kidney injury by Sakran, Razan, Milo, Gai, Jabareen, Ali, Artul, Tareq, Haim, Nissim, Litvak, Michael, Ringelstein-Harlev, Shimrit, Horowitz, Nethanel, Efrati, Edna, Assady, Suheir, Kurnik, Daniel

“…Introduction Acute kidney injury (AKI) after high dose methotrexate (HD-MTX) is associated with delayed MTX-excretion and life-threatening toxicity…”
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Novel Clinical Manifestation of the Known SCN5A D1790G Mutation by Blich, Miry, Efrati, Edna, Marai, Ibrahim, Suleiman, Mahmoud, Gepstein, Lior, Boulous, Monther

“…The D1790G mutation was found in all 24 patients of an extended long QT family but not in 200 chromosomes carried by healthy individuals. We describe a…”
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Risk factors for serious adverse effects of thiopurines in patients with Crohn's disease by Mazor, Yoav, Koifman, Eduard, Elkin, Hela, Chowers, Yehuda, Krivoy, Norberto, Karban, Amir, Efrati, Edna

“…Thiopurines are effective in attaining and maintaining remission in patients with inflammatory bowel diseases (IBD). The major drawback of these drugs are…”
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Transcriptional Regulation of the Pendrin Gene by Rozenfeld, Julia, Efrati, Edna, Adler, Lior, Tal, Osnat, Carrithers, Stephen L., Alper, Seth L., Zelikovic, Israel

“…Pendrin (SLC26A4), a Cl - /anion exchanger encoded by the gene PDS, is highly expressed in the kidney, thyroid and inner ear epithelia and is essential for…”
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The human paracellin-1 gene (hPCLN-1): renal epithelial cell-specific expression and regulation by Efrati, Edna, Arsentiev-Rozenfeld, Julia, Zelikovic, Israel

“…Tubular reabsorption of Mg2+ is mediated by the tight junction protein paracellin-1, which is encoded by the gene PCLN-1 (CLDN16) and exclusively expressed in…”
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Distribution of CYP2C9 and VKORC1 risk alleles for warfarin sensitivity and resistance in the Israeli population by Efrati, Edna, Elkin, Hela, Sprecher, Eli, Krivoy, Norberto

“…This study was designed to delineate the relative frequency of CYP2C9 and VKORC1 polymorphisms known to affect warfarin response in the highly heterogeneous…”
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Pendrin, a Novel Transcriptional Target of the Uroguanylin System by Rozenfeld, Julia, Tal, Osnat, Kladnitsky, Orly, Adler, Lior, Efrati, Edna, Carrithers, Stephen L., Alper, Seth L., Zelikovic, Israel

“…Guanylin (GN) and uroguanylin (UGN) are low-molecular-weight peptide hormones produced mainly in the intestinal mucosa in response to oral salt load. GN and…”
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Pharmacokinetic and pharmacogenetic analysis of oral busulfan in stem cell transplantation: prediction of poor drug metabolism to prevent drug toxicity by Krivoy, Norberto, Zuckerman, Tsila, Elkin, Hela, Froymovich, Lia, Rowe, Jacob M, Efrati, Edna

“…High dose busulfan (BU) has become a mainstay in conditioning regimens for hematopoietic stem cell transplantation (HSCT), despite its unpredictable response,…”
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Individual Meropenem Clearance in Infants on ECMO and CVVHDF is Difficult to Predict: A Case Report and Review of the Literature by Jabareen, Ali, Nassar, Laila, Karasik, Marina, Efrati, Edna, Hadash, Amir, Kassis, Imad, Kurnik, Daniel

“…Meropenem is a broad-spectrum carbapenem antibiotic with mostly renal excretion. Conflicting data are available regarding meropenem pharmacokinetics in…”
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Individual Meropenem Clearance in Infants on ECMO and CVVHDF is Difficult to Predict: A Case Report and Review of the Literature by Jabareen, Ali, Nassar, Laila, Karasik, Marina, Efrati, Edna, Hadash, Amir, Kassis, Imad, Kurnik, Daniel

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An outbreak of severe coagulopathy in northern Israel among users of illicit synthetic cannabinoids adulterated with brodifacoum by Lurie, Yael, Nadir, Yona, Hoffman, Ron, Miller, Asaf, Efrati, Edna, Ring, Gil, Sonenfeld, Dana, Bar, Nitai, Zaidani, Hisam, Strizevsky, Alexander, Asali, Mahdi, Lavon, Ophir, Kurnik, Daniel

“…Adulteration of illicit drugs is a well-known phenomenon that may expose consumers to unexpected adverse effects. We report a large outbreak of severe…”
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Genetic polymorphisms predicting methotrexate blood levels and toxicity in adult non-Hodgkin lymphoma by Avivi, Irit, Zuckerman, Tsila, Krivoy, Norberto, Efrati, Edna

“…Abstract Methotrexate (MTX), a folate antagonist employed for treating a wide range of malignancies, has an extensive interpatient variability, resulting in…”
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Limited Sampling Strategies Supporting Individualized Dose Adjustment of Intravenous Busulfan in Children and Young Adults by Teitelbaum, Zvi, Nassar, Laila, Scherb, Inna, Fink, Dorit, Ring, Gil, Lurie, Yael, Krivoy, Norberto, Bentur, Yedidia, Efrati, Edna, Kurnik, Daniel

“…Therapeutic drug monitoring (TDM) for busulfan supports dose adjustment during conditioning for stem cell transplantation. The authors aimed to develop and…”
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Decreased Systemic Busulfan Exposure After Oral Dosing With Concomitant Levetiracetam Compared To Phenytoin by Artul, Tareq, Henig, Israel, Nassar, Laila, Yehudai-Ofir, Dana, Scherb, MD Inna, Lurie, Yael, Efrati, Edna, Zuckerman, Tsila, Kurnik, Daniel

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The association of the MTHFR C677T polymorphism with inflammatory bowel diseases in the Israeli Jewish population: An example of genetic heterogeneity by Karban, Amir, Feldman, Tzah, Waterman, Matti, Leiba, Ronit, Efrati, Edna

“…MTHFR C677T is a common gene polymorphism that has been shown to be associated with hyperhomocysteinemia. Studies on the role of MTHFR in inflammatory bowel…”
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Molecular mechanisms of epithelial cell-specific expression and regulation of the human anion exchanger (pendrin) gene by Adler, Lior, Efrati, Edna, Zelikovic, Israel

“…Pendrin, a Cl(-)/anion exchanger encoded by the gene PDS, is highly expressed in the kidney, thyroid, and inner ear epithelia and is essential for bicarbonate…”
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Busulfan directly inhibits T cell proliferation through non-anergic cell cycle arrest by Ben-Ami, Eyal, Krivoy, Norberto, Efrati, Edna

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Comparison of everolimus QMS immunoassay on Architect ci4100 and liquid chromatography/mass spectrometry: lack of agreement in organ-transplanted patients by Hoffer, Erica, Kurnik, Daniel, Efrati, Edna, Scherb, Inna, Karasik, Marina, Ring, Gil, Bentur, Yedidia

“…Liquid chromatography with mass spectrometry (LC-MS/MS) is the method of choice for the determination of everolimus whole blood concentrations but is not…”
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The claudin‐16 channel gene is transcriptionally inhibited by 1,25‐dihydroxyvitamin D by Kladnitsky, Orly, Rozenfeld, Julia, Azulay‐Debby, Hilla, Efrati, Edna, Zelikovic, Israel

“…New Findings What is the central question of this study? In the kidney, the bulk of the filtered Mg2+ is reabsorbed in the thick ascending limb by paracellular…”
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