Search Results - "Efimov, G. A."

Experimental models of arthritis in which pathogenesis is dependent on TNF expression by Drutskaya, M. S., Efimov, G. A., Zvartsev, R. V., Chashchina, A. A., Chudakov, D. M., Tillib, S. V., Kruglov, A. A., Nedospasov, S. A.

“…Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by joint damage as well as systemic manifestations. The exact cause of RA is not…”
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Tumor Necrosis Factor and the consequences of its ablation in vivo by Efimov, G.A., Kruglov, A.A., Tillib, S.V., Kuprash, D.V., Nedospasov, S.A.

“…Although TNF has been discovered due to anti-tumor activity, its physiological functions are different. Current knowledge places TNF downstream of many…”
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Design Principles of Airborne Multibeam Receiving APAA Satellite Communication Systems by Efimov, A. G., Kamenev, A. G., Korneev, S. A., Chistyukhin, V. V.

“…The use of active phased antenna arrays (APAAs) makes it possible to redistribute the information capacity of the communication system by scanning independent…”
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Minor histocompatibility antigens represented in HLA-A02:01 and their search strategies by Romanyuk, D. S., Pilunov, A. M., Efimov, G. A., Bogolyubova, A. V., Parovichnikova, E. N.

“…   Minor histocompatibility antigens (MiHAs) are polymorphic peptides on the cell surface derived from self-proteins that are capable to induce an immune…”
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Antibodies to the N-Terminal Domain of Angiotensin-Converting Enzyme (ACE2) That Block Its Interaction with SARS-CoV-2 S Protein by Krut, V. G., Astrakhantseva, I. V., Chuvpilo, S. A., Efimov, G. A., Ambaryan, S. G., Drutskaya, M. S., Nedospasov, S. A.

“…SARS-CoV-2 is a new coronavirus that is the cause of COVID-19 pandemic. To enter the cell, the virus interacts via its surface S protein with…”
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Use of Silicon-Germanium Technology for the Development of Active Microwave Units of Active Electronically Scanned Arrays by Timoshenkov, V. P., Efimov, A. G.

“…The possibility of using new technologies to develop active microwave units of transmit/receive modules is considered. A comparative analysis of technological…”
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T Lymphocytes with Modified Specificity in the Therapy of Malignant Diseases by Vdovin, A. S., Bykova, N. A., Efimov, G. A.

“…Immunotherapy is one of the most rapidly progressing and promising fields in antitumor therapy. It is based on the idea of using immune cells of patient or…”
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Study of the Mechanical Properties of Structural Steels Using Acoustic and Magnetic Methods by Tyutin, M. R., Botvina, L. R., Levin, V. P., Efimov, A. G., Kuzelev, N. R.

“…Mechanical properties of structural steels have been studied upon tensile tests of flat specimens with a stress concentrator using acoustic and magnetic…”
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Methods for in vivo molecular imaging by Kuchmiy, A. A., Efimov, G. A., Nedospasov, S. A.

“…Visualization of single molecules and specific subsets of cells is widely used for studies of biological processes and particularly in immunological research…”
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Modern anti-cytokine therapy of autoimmune diseases by Astrakhantseva, I. V., Efimov, G. A., Drutskaya, M. S., Kruglov, A. A., Nedospasov, S. A.

“…The emergence of genetically engineered biological agents opened new prospects in the treatment of autoimmune and inflammatory diseases. Cytokines responsible…”
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Precision L-Band Analog-Digital Phase Shifter with a 0°–360° Phase Change by Efimov, A. G., Kuptsov, E. O., Martynova, V. P., Spiridonov, A. B., Surin, Yu. V.

“…In modern satellite communication systems and airborne repeaters using an APAR, the receiving and transmitting modules usually consist of discrete phase…”
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Recombinant MHC tetramers for isolation of virus-specific CD8+ cells from healthy donors: Potential approach for cell therapy of posttransplant cytomegalovirus infection by Vdovin, A. S., Filkin, S. Y., Yefimova, P. R., Sheetikov, S. A., Kapranov, N. M., Davydova, Y. O., Egorov, E. S., Khamaganova, E. G., Drokov, M. Y., Kuzmina, L. A., Parovichnikova, E. N., Efimov, G. A., Savchenko, V. G.

“…Patients undergoing allogeneic hematopoietic stem cell transplantation have a high risk of cytomegalovirus reactivation, which in the absence of T-cell…”
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Single-domain antibody-based ligands for immunoaffinity separation of recombinant human lactoferrin from the goat lactoferrin of transgenic goat milk by Tillib, S.V., Privezentseva, M.E., Ivanova, T.I., Vasilev, L.F., Efimov, G.A., Gursky, Y.G., Georgiev, G.P., Goldman, I.L., Sadchikova, E.R.

“…•Single-domain antibodies with high specificity to human lactoferrin are generated.•Generated antibodies are used to efficiently separate human and goat…”
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Modification of Cytotoxic Lymphocytes with T Cell Receptor Specific for Minor Histocompatibility Antigen ACC-1Y by Pilunov, A. M., Kuchmiy, A. A., Sheetikov, S. A., Filkin, S. Y., Romaniuk, D. S., Rosov, F. N., Efimov, G. A.

“…Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only curative therapy for hematopoietic malignancies. The graft-derived donor lymphocytes…”
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Interleukin-6: From molecular mechanisms of signal transduction to physiological properties and therapeutic targeting by Drutskaya, M. S., Nosenko, M. A., Atretkhany, K.-S. N., Efimov, G. A., Nedospasov, S. A.

“…Interleukin-6 (IL-6) is one of the most important proinflammatory cytokines that has a broad spectrum of immunoregulatory properties. The molecular mechanisms…”
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CLINICALLY RELEVANT MINOR HISTOCOMPATIBILITY ANTIGENS FOR RUSSIAN PATIENTS UNDERGOING HEMATOPOIETIC STEM CELL TRANSPLANTATION by Romaniuk, D. S., Khmelevskaya, A. A., Postovskaya, A. M., Malko, D. B., Kuzminova, E. P., Khamaganova, E. G., Efimov, G. A.

“…Hematopoietic stem cell transplantation (HSCT) from healthy donors is used for blood cancer treatment. Alloreactive graft-versus-host disease (GvHD) is one of…”
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Humanization of Murine Monoclonal anti-hTNF Antibody: The F10 Story by Efimov, G. A., Raats, J. M. H., Chirivi, R. G. S., van Rosmalen, J. W. G., Nedospasov, S. A.

“…Tumor necrosis factor (TNF) is a proinflammatory cytokine implicated in pathogenesis of multiple autoimmune and inflammatory diseases. Anti-TNF therapy has…”
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Effect of CTLA4 gene polymorphism on relapse probability among patients with acute leukemias after allogenic hematopoietic stem cells transplantation by Romaniuk, D. S., Khmelevskaya, A. A., Drokov, M. Yu, Popova, N. N., Vasilieva, V. A., Kuzmina, L. A., Efimov, G. A., Parovichnikova, E. N., Savchenko, V. G.

“…Background. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is being widely applied as a therapy for hematological malignancies. The long-term…”
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Development of adaptive eddy-current instruments for flaw sizing by Efimov, A. G.

“…The design of an eddy-current transducer (ECT) equipped with an oscillatory circuit was developed; interrelations between the voltage fed to the flaw detecting…”
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CANCER IMMUNOTHERAPY BASED ON THE BLOCKADE OF IMMUNE CHECKPOINTS by Bogolyubova, A. V., Efimov, G. A., Drutskaya, M. S., Nedospasov, S. A.

“…Immune checkpoints represent the system of inhibitory mechanisms regulating the activation of the immune response, preventing the autoimmune processes and…”
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