Search Results - "Effertz, Thomas"

Phosphoinositol-4,5-Bisphosphate Regulates Auditory Hair-Cell Mechanotransduction-Channel Pore Properties and Fast Adaptation by Effertz, Thomas, Becker, Lars, Peng, Anthony W, Ricci, Anthony J

“…Membrane proteins, such as ion channels, interact dynamically with their lipid environment. Phosphoinositol-4,5-bisphosphate (PIP ) can directly or indirectly…”
Get full text

neural basis of Drosophila gravity-sensing and hearing by Kamikouchi, Azusa, Inagaki, Hidehiko K, Effertz, Thomas, Hendrich, Oliver, Fiala, Andre, Gopfert, Martin C, Ito, Kei

“…The neural substrates that the fruitfly Drosophila uses to sense smell, taste and light share marked structural and functional similarities with ours,…”
Get full text

Direct gating and mechanical integrity of Drosophila auditory transducers require TRPN1 by Effertz, Thomas, Nadrowski, Björn, Piepenbrock, David, Albert, Jörg T, Göpfert, Martin C

“…The identity of the mechanosensitive channel responsible for sound transduction in the ear has remained elusive. Here the authors show, using interferometry,…”
Get full text

A Partial Ossicular Replacement Prosthesis With a Concentric Ball Joint in the Headplate by Bevis, Nicholas, Effertz, Thomas, Beutner, Dirk

“…Objective In passive middle ear prosthetics, rigid implants have proven successful in reconstructing the ossicular chain. However, these cannot fully replicate…”
Get full text

Partial Ossicular Reconstruction With a Novel Ball Joint Prosthesis: The mCLIP ARC Partial Prosthesis by Bevis, Nicholas, Effertz, Thomas, Hüser, Marc, Beutner, Dirk

“…Objective Middle ear surgery involves reconstruction of the ossicular chain, predominately using rigid implants. New middle ear prostheses strive to mimic the…”
Get full text

The impact of tympanic membrane perforations on middle ear transfer function by Bevis, Nicholas, Sackmann, Benjamin, Effertz, Thomas, Lauxmann, Michael, Beutner, Dirk

“…Purpose Injury or inflammation of the middle ear often results in the persistent tympanic membrane (TM) perforations, leading to conductive hearing loss (HL)…”
Get full text

Cholesterol as a tool to probe the role of membrane in cochlear hair cell mechanotransduction by Sam George, Shefin, Effertz, Thomas, Ricci, Anthony J.

Get full text

Evaluation of artifacts of cochlear implant electrodes in cone beam computed tomography by Bevis, Nicholas, Effertz, Thomas, Beutner, Dirk, Gueldner, Christian

“…Purpose Cone Beam Computed Tomography (CBCT) offers a valid alternative to conventional Computed Tomography (CT). A possible radiation dose reduction with the…”
Get full text

Nitinol in Passive Ossicular Reconstruction—First Results From Temporal Bone Experiments by Bevis, Nicholas, Schwarz, David, Pazen, David, Effertz, Thomas, Beutner, Dirk

“…HYPOTHESIS:Nitinol is a suitable material for passive middle ear prosthesis. BACKGROUND:In modern ear microsurgery, the restitution of hearing is tremendously…”
Get full text

Adaptation of Mammalian Auditory Hair Cell Mechanotransduction Is Independent of Calcium Entry by Peng, Anthony W., Effertz, Thomas, Ricci, Anthony J.

“…Adaptation is a hallmark of hair cell mechanotransduction, extending the sensory hair bundle dynamic range while providing mechanical filtering of incoming…”
Get full text

The how and why of identifying the hair cell mechano-electrical transduction channel by Effertz, Thomas, Scharr, Alexandra L., Ricci, Anthony J.

“…Identification of the auditory hair cell mechano-electrical transduction (hcMET) channel has been a major focus in the hearing research field since the 1980s…”
Get full text

Corrigendum: Direct gating and mechanical integrity of Drosophila auditory transducers require TRPN1 by Effertz, Thomas, Nadrowski, Björn, Piepenbrock, David, Albert, Jörg T, Göpfert, Martin C

Get full text

Direct gating and mechanical integrity of Drosophila auditory transducers require TRPN1

Get full text

Erratum: Corrigendum: Direct gating and mechanical integrity of Drosophila auditory transducers require TRPN1 by Effertz, Thomas, Nadrowski, Björn, Piepenbrock, David, Albert, Jörg T, Göpfert, Martin C

Get full text

Correction: Corrigendum: Direct gating and mechanical integrity of Drosophila auditory transducers require TRPN1 by Effertz, Thomas, Nadrowski, Björn, Piepenbrock, David, Albert, Jörg T, Göpfert, Martin C

“…Nat. Neurosci. 15, 1198–1200 (2012); published online 29 July 2012; corrected after print 13 May 2013 In the version of this article initially published, grant…”
Get full text

NompC TRP Channel Is Essential for Drosophila Sound Receptor Function by Effertz, Thomas, Wiek, Robert, Göpfert, Martin C.

“…The idea that the NompC TRPN1 channel is the Drosophila transducer for hearing has been challenged by remnant sound-evoked nerve potentials in nompC nulls…”
Get full text

Designer aminoglycosides prevent cochlear hair cell loss and hearing loss by Huth, Markus E, Han, Kyu-Hee, Sotoudeh, Kayvon, Hsieh, Yi-Ju, Effertz, Thomas, Vu, Andrew A, Verhoeven, Sarah, Hsieh, Michael H, Greenhouse, Robert, Cheng, Alan G, Ricci, Anthony J

“…Bacterial infections represent a rapidly growing challenge to human health. Aminoglycosides are widely used broad-spectrum antibiotics, but they inflict…”
Get full text

Transcuticular optical imaging of stimulus-evoked neural activities in the Drosophila peripheral nervous system by Göpfert, Martin C, Fiala, André, Kamikouchi, Azusa, Wiek, Robert, Effertz, Thomas

“…The nervous system of Drosophila is widely used to study neuronal signal processing because the activities of neurons can be controlled and monitored by cell…”
Get full text

Recent advances in cochlear hair cell nanophysiology: subcellular compartmentalization of electrical signaling in compact sensory cells by Effertz, Thomas, Moser, Tobias, Oliver, Dominik

“…In recent years, genetics, physiology, and structural biology have advanced into the molecular details of the sensory physiology of auditory hair cells. Inner…”
Get full text

Using Drosophila for studying fundamental processes in hearing by Lu, Qianhao, Senthilan, Pingkalai R., Effertz, Thomas, Nadrowski, Björn, Göpfert, Martin C.

“…Apart from detecting sounds, vertebrate ears occasionally produce sounds. These spontaneous otoacoustic emissions are the most compelling evidence for the…”
Get full text