Search Results - "Eerenberg, Anke"

Elevated nucleosome levels in systemic inflammation and sepsis by Zeerleder, Sacha, Zwart, Bas, Wuillemin, Walter A, Aarden, Lucien A, Groeneveld, A. B Johan, Caliezi, Christoph, van Nieuwenhuijze, Annemarie E. M, van Mierlo, Gerard J, Eerenberg, Anke J. M, Lämmle, Bernhard, Hack, C Erik

“…OBJECTIVEMultiple organ dysfunction syndrome is a frequent complication of severe sepsis and septic shock and has a high mortality. We hypothesized that…”
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Elevated nucleosome levels in systemic inflammation and sepsis by Zeerleder, Sacha, Zwart, Bas, Wuillemin, Walter A., Aarden, Lucien A., Groeneveld, A. B. Johan, Caliezi, Christoph, van Nieuwenhuijze, Annemarie E. M., van Mierlo, Gerard J., Eerenberg, Anke J. M., Lämmle, Bernhard, Hack, C. Erik

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Subcutaneous injection of interleukin 12 induces systemic inflammatory responses in humans: implications for the use of IL-12 as vaccine adjuvant by PORTIELJE, Johanna E. A, KRUIT, Wim H. J, EERENBERG, Anke J. M, SCHULER, Martin, SPARREBOOM, Alex, LAMERS, Cor H. J, GRATAMA, Jan-Willem, STOTER, Gerrit, HUBER, Christoph, HACK, C. Erik

“…Interleukin 12 (IL-12) is a cytokine with important regulatory functions bridging innate and adaptive immunity. It has been proposed as an immune adjuvant for…”
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Interleukin 12 induces activation of fibrinolysis and coagulation in humans by Portielje, Johanna E. A., Kruit, Wim H. J., Eerenberg, Anke J. M., Schuler, Martin, Sparreboom, Alex, Lamers, Cor H. J., Bolhuis, Reinder L. H., Stoter, Gerrit, Huber, Christoph, Hack, C. Erik

“…Interleukin 12 (IL‐12) has potential efficacy in malignant, infectious and allergic diseases. Its side‐effects include activation of coagulation and…”
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Complement Activation in Relation to Capillary Leakage in Children with Septic Shock and Purpura by HAZELZET, J. A, DE GROOT, R, VAN MIERLO, G, JOOSTEN, K. F. M, VAN DER VOORT, E, EERENBERG, A, SUUR, M. H, HOP, W. C. J, HACK, C. E

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Heparin-protamine complexes and C-reactive protein induce activation of the classical complement pathway: studies in patients undergoing cardiac surgery and in vitro by Bruins, P, te Velthuis, H, Eerenberg-Belmer, A J, Yazdanbakhsh, A P, de Beaumont, E M, Eijsman, L, Trouwborst, A, Hack, C E

“…The administration of protamine to patients undergoing cardiopulmonary bypass (CPB) to neutralize heparin and to reduce the risk of bleeding, induces…”
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Administration of C1 inhibitor reduces neutrophil activation in patients with sepsis by Zeerleder, Sacha, Caliezi, Christoph, van Mierlo, Gerard, Eerenberg-Belmer, Anke, Sulzer, Irmela, Hack, C Erik, Wuillemin, Walter A

“…Forty patients with severe sepsis or septic shock recently received C1 inhibitor. In the present study we studied the effect of C1 inhibitor therapy on…”
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Inhibition of Endotoxin-Induced Cytokine Release and Neutrophil Activation in Humans by Use of Recombinant Bactericidal/Permeability-Increasing Protein by von der Möhlen, Marijke A. M., Kimmings, A. Nikola, Wedel, Nancy I., Mevissen, Marcel L. C. M., Jansen, Jaap, Friedmann, Nadav, Lorenz, Todd J., Nelson, Betty J., White, Mark L., Bauer, Robert, Hack, C. Erik, Eerenberg, Anke J. M., van Deventer, Sander J. H.

“…To investigate the effects of a recombinant endotoxin-binding protein, bactericidal/permeabilityincreasing protein (rBPI23), on cytokine release and neutrophil…”
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A phase I study of recombinant human C1 inhibitor in asymptomatic patients with hereditary angioedema by van Doorn, Martijn B.A., Burggraaf, Jacobus, van Dam, Tijtje, Eerenberg, Anke, Levi, Marcel, Hack, Cornelis E., Schoemaker, Rik C., Cohen, Adam F., Nuijens, Jan

“…Hereditary angioedema (HAE) is a congenital disorder with recurrent attacks of localized swelling of submucosal tissue, subcutaneous tissue, or both caused by…”
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Elimination of interleukin 6 attenuates coagulation activation in experimental endotoxemia in chimpanzees by VAN DER POLL, T, HACK, C. E, AARDEN, L. A, TEN CATE, H, VAN DEVENTER, S. J. H, EERENBERG, A. J. M, DE GROOT, E. R, JANSEN, J, GALLATI, H, BÜLLER, H. R, TEN CATE, J. W

“…The role of interleukin 6 (IL-6) in the toxic sequelae of sepsis is controversial. To assess the part of IL-6 in inflammatory responses to endotoxin, we…”
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Interleukin-2 induces activation of coagulation and fibrinolysis: resemblance to the changes seen during experimental endotoxaemia by Baars, J W, de Boer, J P, Wagstaff, J, Roem, D, Eerenberg-Belmer, A J, Nauta, J, Pinedo, H M, Hack, C E

“…The administration of Interleukin-2 (IL-2) causes the release or generation of other cytokines such as tumour necrosis factor (TNF) which, by disturbing the…”
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Inactivation of Factor XIa in Human Plasma Assessed by Measuring Factor XIa-Protease Inhibitor Complexes: Major Role for C1-Inhibitor by Wuillemin, Walter A., Minnema, Monique, Meijers, Joost C.M., Roem, Dorina, Eerenberg, Anke J.M., Nuijens, Jan H., Cate, Hugo ten, Hack, C.Erik

“…From experiments with purified proteins, it has been concluded that factor XIa (FXIa) is inhibited in plasma mainly by α1-antitrypsin (a1AT), followed by…”
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IL-1 beta does not cause neutrophil degranulation but does lead to IL- 6, IL-8, and nitrite/nitrate release when used in patients with cancer by Ogilvie, AC, Hack, CE, Wagstaff, J, van Mierlo, GJ, Erenberg, AJ, Thomsen, LL, Hoekman, K, Rankin, EM

“…The use of IL-1 in humans is associated with dose-limiting toxicity which resembles that of TNF-alpha or IL-2. Activation of neutrophils is thought to…”
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Plasma levels of C1 inhibitor complexes and cleaved C1 inhibitor in patients with hereditary angioneurotic edema by CUGNO, M, NUIJENS, J, HACK, E, EERENBERG, A, FRANGI, D, AGOSTONI, A, CICARDI, M

“…C1- inhibitor (C1(-)-Inh) catabolism in plasma of patients with hereditary angioneurotic edema (HANE) was assessed by measuring the complexes formed by…”
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Activated cytotoxic T cells and NK cells in severe sepsis and septic shock and their role in multiple organ dysfunction by Zeerleder, Sacha, Hack, C. Erik, Caliezi, Christoph, van Mierlo, Gerard, Eerenberg-Belmer, Anke, Wolbink, Angela, Wuillenmin, Walter A.

“…To evaluate the role of activated cytotoxic cells in patients with severe sepsis ( n = 32) or septic shock ( n = 8), direct (granzymes A and B) as well as…”
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C1-esterase inhibitor substitution in sepsis by Hack, C E, Voerman, H J, Eisele, B, Keinecke, H O, Nuijens, J H, Eerenberg, A J, Ogilvie, A, Strack van Schijndel, R J, Delvos, U, Thijs, L G

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Activation of the contact system in insect-sting anaphylaxis : association with the development of angioedema and shock by VAN DER LINDEN, P.-W. G, HACK, C. E, EERENBERG, A. J. M, STRUYVENBERG, A, VAN DER ZWAN, J. K

“…A postulated role of the contact system in anaphylactic reactions to insect stings was investigated. During prospective, in-hospital sting challenge, we…”
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Increased Plasma Levels of Interleukin-6 in Sepsis by Hack, C. Erik, De Groot, Els R., Fert-Bersma, Richelle J.F., Nuijens, Jan H., Strack Van Schijndel, Rob J.M., Eerenberg-Belmer, Anke J.M., Thijs, Lambertus G., Aarden, Lucien A.

“…lnterleukin-6 (IL-6) is likely to be an important mediator of the inflammatory response. We measured levels of this cytokine in plasma samples from 37 patients…”
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Studies on the contact system of coagulation during therapy with high doses of recombinant IL-2: implications for septic shock by Hack, C E, Wagstaff, J, Strack van Schijndel, R J, Eerenberg, A J, Pinedo, H M, Thijs, L G, Nuijens, J H

“…Patients treated with high doses of interleukin-2 (IL-2) because of cancer, develop hemodynamic and vasopermeability changes, that resemble those observed in…”
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Lack of activation of C1, despite circulating immune complexes detected by two C1q methods, in patients with rheumatoid arthritis by Hack, C E, Eerenberg-Belmer, A J, Lim, U G, Haverman, J, Aalberse, R C

“…The activation of C1 by circulating immune complexes in patients with rheumatoid arthritis was investigated. C1rC1s(C1-In)2 complexes in EDTA-plasma,…”
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