Search Results - "Eeles, Ros A."

A polymorphism in the promoter of FRAS1 is a candidate SNP associated with metastatic prostate cancer by Wang, Victoria, Geybels, Milan S., Jordahl, Kristina M., Gerke, Travis, Hamid, Anis, Penney, Kathryn L., Markt, Sarah C., Freedman, Matthew, Pomerantz, Mark, Lee, Gwo‐Shu M., Rana, Huma, Börnigen, Daniela, Rebbeck, Timothy R., Huttenhower, Curtis, Eeles, Ros A., Stanford, Janet L., Consortium, Practical, Berndt, Sonja I., Claessens, Frank, Sørensen, Karina D., Park, Jong Y., Vega, Ana, Usmani, Nawaid, Mucci, Lorelei, Sweeney, Christopher J.

“…Background Inflammation and one of its mediators, NF‐kappa B (NFκB), have been implicated in prostate cancer carcinogenesis. We assessed whether germline…”
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Cancers in BRCA1 and BRCA2 Carriers and in Women at High Risk for Breast Cancer: MR Imaging and Mammographic Features by GILBERT, FionaJ, WARREN, Ruth M. L, KWAN-LIM, Gek, THOMPSON, Deborah J, EELES, Ros A, GARETH EVANS, D, LEACH, Martin O

“…To review imaging features of screening-detected cancers on images from diagnostic and prior examinations to identify specific abnormalities to aid earlier…”
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Common variation in Kallikrein genes KLK5 , KLK6 , KLK12 , and KLK13 and risk of prostate cancer and tumor aggressiveness by Lose, Felicity, Ph.D, Batra, Jyotsna, Ph.D, O'Mara, Tracy, B.Sc.(Hons), Fahey, Paul, Ph.D, Marquart, Louise, B.Econ., B.Sc., B.App.Sc.(Hons), Eeles, Ros A., M.A., Ph.D., F.R.C.P., F.R.C.R, Easton, Douglas F., Ph.D, Al Olama, Ali Amin, Ph.D, Kote-Jarai, Zsofia, Ph.D, Guy, Michelle, Ph.D, Muir, Kenneth, Ph.D, Lophatananon, Artitaya, Ph.D, Rahman, Aneela A., Ph.D, Neal, David E., M.S., F.R.C.S, Hamdy, Freddie C., M.D., F.R.C.S, Donovan, Jenny L., Ph.D, Chambers, Suzanne, Ph.D, Gardiner, Robert A., M.D., F.R.C.S., F.R.A.C.S, Aitken, Joanne F., Ph.D, Yaxley, John, M.D., F.R.A.C.S, Alexander, Kimberly, Ph.D, Clements, Judith A., Ph.D, Spurdle, Amanda B., Ph.D, Kedda, Mary-Anne, Ph.D

“…Abstract The human tissue Kallikrein family consists of 15 genes with the majority shown to be differentially expressed in cancers and/or indicators of cancer…”
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SCREENING FOR PROSTATE CANCER: THE WAY AHEAD by Kirby, Roger S., Eeles, Ros A., Kote‐Jarai, Zsofia, Guy, Michelle, Easton, Doug, Fitzpatrick, John M.

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BARCODE 1: A pilot study investigating the use of genetic profiling to identify men in the general population with the highest risk of prostate cancer to invite for targeted screening by Eeles, Ros A., ni Raghallaigh, Holly

“…Abstract only 1505 Background: Genetic profiling could be used to target population screening for prostate cancer (PrCa). Approximately 170 single nucleotide…”
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ATM protein overexpression in prostate tumors: Possible role in telomere maintenance by ANGELE, Sandra, FALCONER, Alison, FOSTER, Christopher S, TANIERE, Phillipe, EELES, Ros A, HALL, Janet

“…It has been postulated that telomere dysfunction and telomerase activation have important roles in prostate tumorigenesis. Since the ataxia-telangiectasia…”
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The proteomic approach to urological biomarkers by Kommu, Sashi, Sharifi, Reza, Eeles, Ros A.

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The BARCODE1 study in primary care: Early results targeting men with increased genetic risk of developing prostate cancer—Examining the interim data from a community-based screening program using polygenic risk score to target screening by McHugh, Jana Kathlyn, ni Raghallaigh, Holly, Bancroft, Elizabeth, Kote-Jarai, Zsofia, Benafif, Sarah, Eeles, Ros A.

“…Abstract only 231 Background: A significant proportion of Prostate cancer (PrCa) risk is attributable to heritable risk factors of which only a minority are…”
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The profile study: Prostate cancer screening in men of Black African and African Caribbean ancestry—Early results by Kinsella, Netty, McHugh, Jana Kathlyn, McGrowder, Eva, James, Denzil, Saunders, Ed, Bancroft, Elizabeth, Kote-Jarai, Zsofia, Eeles, Ros A.

“…306 Background: Heritable risk factors account for a significant proportion of prostate cancer (PrCa) risk, of which only a minority are high risk Mendelian…”
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The BARCODE1 pilot study targeting men with increased genetic risk of developing prostate cancer: Examining the feasibility of a community-based screening program using polygenic risk score to target screening by McHugh, Jana Kathlyn, Benafif, Sarah, ni Raghallaigh, Holly, Bancroft, Elizabeth, Kote-Jarai, Zsofia, Eeles, Ros A.

“…Abstract only 227 Background: A significant proportion of Prostate cancer (PrCa) risk is attributable to heritable risk factors of which only a minority are…”
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Whole genome germline sequencing: Its role in general health screening in family practice, the first study in the UK by Eeles, Ros A., Sandberg, Michael, Pichert, Gabriella C., Side, Lucy, Homfray, Tessa, Jones, Ann-Britt, Hicks, Sophie, Bancroft, Elizabeth

“…10510 Background: Whole genome sequencing (WGS) is now possible due to improvements in next generation sequencing technology. This gives the opportunity to…”
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Germline sequencing of advanced prostate cancer patients in the BARCODE2 study by Benafif, Sarah, Whitmore, Ian, Anokian, Ezequiel, Cieza-Borrella, Clara, Saunders, Ed, Kote-Jarai, Zsofia, Eeles, Ros A.

“…Abstract only…”
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Baseline screening and psychosocial results from the UK SIGNIFY study: A whole-body MRI screening study in TP53 mutation carriers and matched controls by Eeles, Ros A., Bancroft, Elizabeth, Saya, Sibel, Killick, Emma, Whitehouse, Richard W, Koh, Dow-Mu, Sohaib, Syed A, Walker, Leslie

“…Abstract only 1520 Background: In the United Kingdom, current screening guidelines for TP53 germline mutation carriers solely recommends annual breast MRI,…”
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DNA repair gene panel mutations in young onset prostate cancer cases in the by Eeles, Ros A., Leongamornlert, Daniel, Saunders, Ed, Wakerell, Sarah, Whitmore, Ian, Dadaev, Tokhir, Borrella, Clara Cieza, Govindasami, Koveela, Brook, Mark, Lophatananon, Artitaya, Muir, Kenneth, Conti, David V, Kote-Jarai, Zsofia

“…Abstract only 18 Background: Prostate cancer (PrCa) is the most common solid tumour in men in the Western world. There is substantial evidence that PrCa…”
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Prostate cancer by Attard, Gerhardt, Parker, Chris, Eeles, Ros A, Schröder, Fritz, Tomlins, Scott A, Tannock, Ian, Drake, Charles G, de Bono, Johann S

“…Much progress has been made in research for prostate cancer in the past decade. There is now greater understanding for the genetic basis of familial prostate…”
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Prostate cancer by Attard, Gerhardt, Parker, Chris, Eeles, Ros A, Schröder, Fritz, Tomlins, Scott A, Tannock, Ian, Drake, Charles G, de Bono, Johann S

“…Much progress has been made in research for prostate cancer in the past decade. There is now greater understanding for the genetic basis of familial prostate…”
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Prostate cancer by Attard, Gerhardt, Parker, Chris, Eeles, Ros A, Schröder, Fritz, Tomlins, Scott A, Tannock, Ian, Drake, Charles G, de Bono, Johann S

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Prostate cancer by Attard, Gerhardt, Parker, Chris, Eeles, Ros A, Schroder, Fritz, Tomlins, Scott A, Tannock, Ian, Drake, Charles G, de Bono, Johann S

“…Much progress has been made in research for prostate cancer in the past decade. There is now greater understanding for the genetic basis of familial prostate…”
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Identification of men with a genetic predisposition to prostate cancer: Targeted screening in men at higher genetic risk and controls—The IMPACT study by Eeles, Ros A., Bancroft, Elizabeth, Page, Elizabeth, Castro, Elena, Taylor, Natalie

“…Abstract only 12 Background: IMPACT is a multi-national targeted prostate cancer screening study of men with a known germline mutation which is thought to…”
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Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers to detect clinically significant disease: Results from the initial screening round of the IMPACT study by Mikropoulos, Christos, Castro, Elena, Bancroft, Elizabeth, Page, Elizabeth, Taylor, Natalie, Ahmed, Mahbubl, Goh, Chee Leng, Eeles, Ros A.

“…Abstract only 8 Background: Men with germline BRCA1/2 mutations have a higher risk of developing prostate cancer (PrCa) than non-carriers. IMPACT is an…”
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