Search Results - "Eelco Wallaart, T"

Isolation and Characterization of Two Germacrene A Synthase cDNA Clones from Chicory by Bouwmeester, Harro J., Jan Kodde, Francel W. A. Verstappen, Iris G. Altug, Jan-Willem de Kraker, T. Eelco Wallaart

“…Chicory (Cichorium intybus) sesquiterpene lactones were recently shown to be derived from a common sesquiterpene intermediate, (+)-germacrene A. Germacrene A…”
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Amorpha-4,11-diene synthase: cloning and functional expression of a key enzyme in the biosynthetic pathway of the novel antimalarial drug artemisinin by Wallaart, T. Eelco, Bouwmeester, Harro J., Hille, Jacques, Poppinga, Lucas, Maijers, Niels C. A.

“…The sesquiterpenoid artemisinin, isolated from the plant Artemisia annua L., and its semi-synthetic derivatives are a new and very effective group of…”
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Seasonal variation of artemisinin and its biosynthetic precursors in plants of Artemisia annua of different geographical origin: proof for the existence of chemotypes by Wallaart, T E, Pras, N, Beekman, A C, Quax, W J

“…The time course of the levels of artemisinin, its biosynthetic precursors and the biosynthetically related sesquiterpenes was monitored during a vegetation…”
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Isolation and Identification of Dihydroartemisinic Acid Hydroperoxide from Artemisia annua:  A Novel Biosynthetic Precursor of Artemisinin by Wallaart, T. Eelco, Pras, Niesko, Quax, Wim J

“…Dihydroartemisinic acid hydroperoxide (2) was isolated for the first time as a natural product from the plant Artemisia annua in a 29% yield. Its structure was…”
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Isolation and Identification of Dihydroartemisinic Acid from Artemisia annua and Its Possible Role in the Biosynthesis of Artemisinin by Wallaart, T. Eelco, van Uden, Wim, Lubberink, Heidi G. M, Woerdenbag, Herman J, Pras, Niesko, Quax, Wim J

“…Dihydroartemisinic acid (2) was isolated as a natural product from Artemisia annua in a 66% yield, and its structure was confirmed by 1H and 13C NMR…”
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Seasonal variations of Artemisinin and its biosynthetic precursors in tetraploid Artemisia annua plants compared with the diploid wild-type by Eelco Wallaart, T, Pras, N, Quax, W J

“…Using colchicine we induced tetraploidy in Artemisia annua L. plants. During a vegetation period we monitored the time course of the levels of artemisinin, its…”
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Amorpha-4,11-diene synthase catalyses the first probable step in artemisinin biosynthesis by Bouwmeester, Harro J., Wallaart, T.Eelco, Janssen, Michiel H.A., van Loo, Bert, Jansen, Ben J.M., Posthumus, Maarten A., Schmidt, Claus O., De Kraker, Jan-Willem, König, Wilfried A., Franssen, Maurice C.R.

“…The endoperoxide sesquiterpene lactone artemisinin and its derivatives are a promising new group of drugs against malaria. Artemisinin is a constituent of the…”
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Isolation and Characterization of Two Germacrene A Synthase cDNA Clones from Chicory1 by Bouwmeester, Harro J., Kodde, Jan, Verstappen, Francel W.A., Altug, Iris G., de Kraker, Jan-Willem, Wallaart, T. Eelco

“…Chicory ( Cichorium intybus ) sesquiterpene lactones were recently shown to be derived from a common sesquiterpene intermediate, (+)-germacrene A. Germacrene A…”
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