Search Results - "Edwin Haas"

Canonical Wnt Signaling Regulates Hematopoiesis in a Dosage-Dependent Fashion by Luis, Tiago C., Naber, Brigitta A.E., Roozen, Paul P.C., Brugman, Martijn H., de Haas, Edwin F.E., Ghazvini, Mehrnaz, Fibbe, Willem E., van Dongen, Jacques J.M., Fodde, Riccardo, Staal, Frank J.T.

“…Canonical Wnt signaling has been implicated in the regulation of hematopoiesis. By employing a Wnt-reporter mouse, we observed that Wnt signaling is…”
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C1q-Dependent Dendritic Cell Cross-Presentation of In Vivo-Formed Antigen-Antibody Complexes by Ho, Nataschja I, Camps, Marcel G M, de Haas, Edwin F E, Trouw, Leendert A, Verbeek, J Sjef, Ossendorp, Ferry

“…Dendritic cells (DCs) are specialized in Ag engulfment via a wide variety of uptake receptors on their cell surface. In the present study we investigated Ag…”
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Sustained cross‐presentation capacity of murine splenic dendritic cell subsets in vivo by Ho, Nataschja I., Camps, Marcel G. M., Haas, Edwin F. E., Ossendorp, Ferry

“…An exclusive feature of dendritic cells (DCs) is their ability to cross‐present exogenous antigens in MHC class I molecules. We analyzed the fate of protein…”
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Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation by Luis, Tiago C., Weerkamp, Floor, Naber, Brigitta A.E., Baert, Miranda R.M., de Haas, Edwin F.E., Nikolic, Tatjana, Heuvelmans, Sjanneke, De Krijger, Ronald R., van Dongen, Jacques J.M., Staal, Frank J.T.

“…Canonical Wnt signaling has been implicated in various aspects of hematopoiesis. Its role is controversial due to different outcomes between various inducible…”
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Development of a diverse human T-cell repertoire despite stringent restriction of hematopoietic clonality in the thymus by Brugman, Martijn H., Wiekmeijer, Anna-Sophia, van Eggermond, Marja, Wolvers-Tettero, Ingrid, Langerak, Anton W., de Haas, Edwin F. E., Bystrykh, Leonid V., van Rood, Jon J., de Haan, Gerald, Fibbe, Willem E., Staal, Frank J. T.

“…The fate and numbers of hematopoietic stem cells (HSC) and their progeny that seed the thymus constitute a fundamental question with important clinical…”
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Ig Gene Rearrangement Steps Are Initiated in Early Human Precursor B Cell Subsets and Correlate with Specific Transcription Factor Expression by van Zelm, Menno C, van der Burg, Mirjam, de Ridder, Dick, Barendregt, Barbara H, de Haas, Edwin F. E, Reinders, Marcel J. T, Lankester, Arjan C, Revesz, Tom, Staal, Frank J. T, van Dongen, Jacques J. M

“…The role of specific transcription factors in the initiation and regulation of Ig gene rearrangements has been studied extensively in mouse models, but data on…”
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Beyond livestock carrying capacity in the Sahelian and Sudanian zones of West Africa by Rahimi, Jaber, Haas, Edwin, Grote, Rüdiger, Kraus, David, Smerald, Andrew, Laux, Patrick, Goopy, John, Butterbach-Bahl, Klaus

“…We applied the process-based model, LandscapeDNDC, to estimate feed availability in the Sahelian and Sudanian agro-ecological zones of West Africa as a basis…”
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Overexpression of LMO2 causes aberrant human T-Cell development in vivo by three potentially distinct cellular mechanisms by Wiekmeijer, Anna-Sophia, Pike-Overzet, Karin, Brugman, Martijn H, van Eggermond, Marja C.J.A, Cordes, Martijn, de Haas, Edwin F.E, Li, Yunlei, Oole, Edwin, van IJcken, Wilfred F.J, Egeler, R. Maarten, Meijerink, Jules P, Staal, Frank J.T

“…Overexpression of LMO2 is known to be one of the causes of T-cell acute lymphoblastic leukemia (T-ALL) development; however, the mechanisms behind its…”
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New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling by Dik, Willem A, Pike-Overzet, Karin, Weerkamp, Floor, de Ridder, Dick, de Haas, Edwin F E, Baert, Miranda R M, van der Spek, Peter, Koster, Esther E L, Reinders, Marcel J T, van Dongen, Jacques J M, Langerak, Anton W, Staal, Frank J T

“…To gain more insight into initiation and regulation of T cell receptor (TCR) gene rearrangement during human T cell development, we analyzed TCR gene…”
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Wnt Signaling in the Thymus Is Regulated by Differential Expression of Intracellular Signaling Molecules by Weerkamp, Floor, Baert, Miranda R. M., Naber, Brigitta A. E., Koster, Esther E. L., de Haas, Edwin F. E., Atkuri, Kondala R., van Dongen, Jacques J. M., Herzenberg, Leonard A., Staal, Frank J. T.

“…Wnt signaling is essential for T cell development in the thymus, but the stages in which it occurs and the molecular mechanisms underlying Wnt responsiveness…”
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Human thymus contains multipotent progenitors with T/B lymphoid, myeloid, and erythroid lineage potential by Weerkamp, Floor, Baert, Miranda R.M., Brugman, Martijn H., Dik, Willem A., de Haas, Edwin F.E., Visser, Trudi P., de Groot, Christianne J.M., Wagemaker, Gerard, van Dongen, Jacques J.M., Staal, Frank J.T.

“…It is a longstanding question which bone marrow–derived cell seeds the thymus and to what level this cell is committed to the T-cell lineage. We sought to…”
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Evaluation of LandscapeDNDC Model Predictions of CO2 and N2O Fluxes from an Oak Forest in SE England by Shirley M. Cade, Kevin C. Clemitshaw, Saúl Molina-Herrera, Rüdiger Grote, Edwin Haas, Matthew Wilkinson, James I. L. Morison, Sirwan Yamulki

“…Process-based biogeochemical models are valuable tools to evaluate impacts of environmental or management changes on the greenhouse gas (GHG) balance of forest…”
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Wnt Target Genes Identified by DNA Microarrays in Immature CD34+ Thymocytes Regulate Proliferation and Cell Adhesion by Staal, Frank J. T, Weerkamp, Floor, Baert, Miranda R. M, van den Burg, Caroline M. M, van Noort, Mascha, de Haas, Edwin F. E, van Dongen, Jacques J. M

“…The thymus is seeded by very small numbers of progenitor cells that undergo massive proliferation before differentiation and rearrangement of TCR genes occurs…”
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Development of an in vivo model to study clonal lineage relationships in hematopoietic cells using Brainbow2.1/Confetti mice by de Roo, Jolanda Jd, Vloemans, Sandra A, Vrolijk, Hans, de Haas, Edwin Fe, Staal, Frank Jt

“…Hematopoietic stem cells maintain the homeostasis of all blood cell progeny during development and repopulation-demanding events. To study the lineage…”
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Age-related changes in the cellular composition of the thymus in children by Weerkamp, Floor, de Haas, Edwin F.E., Naber, Brigitta A.E., Comans-Bitter, W. Marieke, Bogers, Ad J.J.C., van Dongen, Jacques J.M., Staal, Frank J.T.

“…T-cell development in the thymus is an extensively studied subject, mainly in mice. Nevertheless, the normal composition and cell numbers of the noninvoluted…”
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Closing the N-Budget: How Simulated Groundwater-Borne Nitrate Supply Affects Plant Growth and Greenhouse Gas Emissions on Temperate Grassland by Liebermann, Ralf, Breuer, Lutz, Houska, Tobias, Klatt, Steffen, Kraus, David, Haas, Edwin, Müller, Christoph, Kraft, Philipp

“…European groundwater reservoirs are frequently subject to reactive nitrogen pollution (Nr) owing to the intensive use of nitrogen (N) fertilizer and animal…”
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Simulation of CO2 Fluxes in European Forest Ecosystems with the Coupled Soil-Vegetation Process Model “LandscapeDNDC” by Saúl Molina-Herrera, Rüdiger Grote, Ignacio Santabárbara-Ruiz, David Kraus, Steffen Klatt, Edwin Haas, Ralf Kiese, Klaus Butterbach-Bahl

“…CO2 exchange processes in forest ecosystems are of profound ecological and economic importance, meaning there is a need for generally applicable simulation…”
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Isolation of human and mouse hematopoietic stem cells by Ng, Yuk Yin, Baert, Miranda R M, de Haas, Edwin F E, Pike-Overzet, Karin, Staal, Frank J T

“…Hematopoietic stem cells (HSC) are rare with estimated frequencies of 1 in 10,000 bone marrow cells and 1 in every 100,000 blood cells. The most important…”
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Indirect Tensile Test (IDT) to Determine Asphalt Mixture Performance Indicators during Quality Control Testing in New Jersey by Bennert, Thomas, Haas, Edwin, Wass, Edward

“…In recent years, there has been a growing interest in incorporating performance testing during the mixture design and quality control testing of asphalt…”
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Long term impact of residue management on soil organic carbon stocks and nitrous oxide emissions from European croplands by Haas, Edwin, Carozzi, Marco, Massad, Raia Silvia, Butterbach-Bahl, Klaus, Scheer, Clemens

“…Application of crop residues to agricultural fields is a significant source of the greenhouse gas nitrous oxide (N2O) and an essential factor affecting the…”
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