Search Results - "Edwards, Seth"

Broken up but still living together: how ARGONAUTE's retention of cleaved fragments explains its role during chromatin modification by Edwards, Seth A, Slotkin, R Keith

“…Throughout the eukaryotic kingdoms, small RNAs direct chromatin modification. ARGONAUTE proteins sit at the nexus of this process, linking the small RNA…”
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Enhanced osteogenesis of mesenchymal stem cells encapsulated in injectable microporous hydrogel by Edwards, Seth D., Ganash, Mrinal, Guan, Ziqiang, Lee, Jeil, Kim, Young Jo, Jeong, Kyung Jae

“…Delivery of therapeutic stem cells to treat bone tissue damage is a promising strategy that faces many hurdles to clinical translation. Among them is the…”
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Improved biocompatibility of dendrimer-based gene delivery by histidine-modified nuclear localization signals by Lee, Jeil, Kwon, Yong-Eun, Edwards, Seth D., Guim, Hwanuk, Jae Jeong, Kyung

“…[Display omitted] Polyamidoamine (PAMAM) dendrimers have been explored as an alternative to polyethylenimine (PEI) as a gene delivery carrier because of their…”
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Transposase-assisted target-site integration for efficient plant genome engineering by Liu, Peng, Panda, Kaushik, Edwards, Seth A., Swanson, Ryan, Yi, Hochul, Pandesha, Pratheek, Hung, Yu-Hung, Klaas, Gerald, Ye, Xudong, Collins, Megan V., Renken, Kaili N., Gilbertson, Larry A., Veena, Veena, Hancock, C. Nathan, Slotkin, R. Keith

“…The current technologies to place new DNA into specific locations in plant genomes are low frequency and error-prone, and this inefficiency hampers…”
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Assessment of Posttransplant Bacteremia Caused by Extended-Spectrum Beta-Lactamase-Producing Gram-Negative Bacteria Among Kidney Transplant Recipients by Tilley, Madeleine S, Edwards, Seth W, Brown, Matthew L, Li, Peng, Mehta, Shikha, Walker, Jeremey, Gutierrez, Kristofer C

“…Extended-spectrum beta-lactamase-producing gram-negative rods (ESBL-GNR) are a rising cause of bacteremia in kidney transplant recipients (KT). The study…”
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Melanin Zinc Complex as a Biocompatible Agent for Clearing Bacteremia by Eliato, Tahmineh Rahmani, Edwards, Seth, Tian, Zhen, Andam, Cheryl P., Jeong, Kyung Jae, Kim, Young Jo

“…Sepsis, whole‐body inflammation caused by the contamination of blood by bacteria and endotoxins, affects millions of patients annually with high mortality…”
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Fast-Curing Injectable Microporous Hydrogel for In Situ Cell Encapsulation by Edwards, Seth D., Hou, Shujie, Brown, Jason M., Boudreau, Ryann D., Lee, Yuhan, Kim, Young Jo, Jeong, Kyung Jae

“…Injectable hydrogels have previously demonstrated potential as a temporary scaffold for tissue regeneration or as a delivery vehicle for cells, growth factors,…”
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Challenges in management of invasive fungal infections in stem cell transplant by Walker, Jeremey, Edwards, W. Seth, Hall, Nicole M., Pappas, Peter G.

“…Invasive fungal infections cause significant morbidity and mortality in hematopoietic stem cell transplant recipients. In order to minimize these infections,…”
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Model-Informed Precision Dosing Improves Outcomes in Patients Receiving Vancomycin for Gram-Positive Infections by Hall, Nicole M, Brown, Matthew L, Edwards, W Seth, Oster, Robert A, Cordell, Will, Stripling, Joshua

“…Consensus guidelines for dosing and monitoring of vancomycin recommend collection of 2 serum concentrations to estimate an area under the curve/minimum…”
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A multi-interpenetrating network (IPN) hydrogel with gelatin and silk fibroin by Park, Shiwha, Edwards, Seth, Hou, Shujie, Boudreau, Ryann, Yee, Rachel, Jeong, Kyung Jae

“…A mechanically strong composite hydrogel was produced based on an interpenetrating network (IPN) between gelatin and silk fibroin. When two layers of the IPN…”
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Outcomes of Daptomycin Plus Ceftaroline Versus Alternative Therapy for Persistent Methicillin-resistant Staphylococcus aureus (MRSA) Bacteremia by Patel, Darshan, Brown, Matthew L., Edwards, Seth, Oster, Robert A., Stripling, Joshua

“…The purpose of this study was to evaluate both efficacy and safety of combination therapy with daptomycin plus ceftaroline (DAP/CPT) versus alternative therapy…”
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Injectable Macroporous Hydrogel Formed by Enzymatic Cross-Linking of Gelatin Microgels by Hou, Shujie, Lake, Rachel, Park, Shiwha, Edwards, Seth, Jones, Chante, Jeong, Kyung Jae

“…Injectable hydrogels can be useful tools for facilitating wound healing since they conform to the irregular shapes of wounds, serving as a temporary matrix…”
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Outcomes of Daptomycin Plus Ceftaroline Versus Alternative Therapy for Persistent Methicillin-resistant Staphylococcus aureus (MRSA) Bacteraemia by Patel, Darshan, Brown, Matthew L., Edwards, Seth, Oster, Robert A., Stripling, Joshua

“…•Persistent methicillin-resistant Staphylococcus aureus bacteraemia (MRSAB) significantly increases mortality risk•There is a lack of data for the ideal…”
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Effectiveness of Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Screening for Reduction of Vancomycin Use for Pneumonia by Snellgrove, Shannon, Brown, Matthew, Edwards, Seth, Leal, Sixto, Bryan, Allen, Pappas, Peter, Lee, Rachael

“…Background: Methicillin-resistant Staphylococcus aureus (MRSA) nasal colonization has been a well-established risk for developing MRSA pneumonia. In previous…”
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Melanin Zinc Complex as a Biocompatible Agent for Clearing Bacteremia (Adv. Mater. Interfaces 5/2024) by Eliato, Tahmineh Rahmani, Edwards, Seth, Tian, Zhen, Andam, Cheryl P., Jeong, Kyung Jae, Kim, Young Jo

“…Blood Cleansing In article 2300369, Kyung Jae Jeong, Young Jo Kim, and co‐workers demonstrate the use of the biologically‐derived eumelanin pigment to capture…”
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Embedding intelligence by Edwards, Seth

“…Computational designer Seth Edwards of the Design Technology (DT) group at Grimshaw, discusses the firm's specialisation in complex geometry, rapid prototyping…”
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Embedding Intelligence: Architecture and Computation at Grimshaw, NY by Edwards, Seth

“…Research and development at Grimshaw is concentrated in two groups: Design Technology (DT) and Industrial Design (ID). Seth Edwards from Grimshaw's DT group…”
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Gelatin-Based Microporous Injectable Hydrogels for In Situ Stem Cell Encapsulation by Edwards, Seth David

“…In this dissertation, I developed and investigated gelatin-based microporous injectable hydrogels for the encapsulation of stem cells for multiple applications…”
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Improved transfection efficiency and reduced cytotoxicity of PAMAM derivatives by Histidine- Modified Nuclear Localization Signals by Lee, Jeil, Kwon, Yong-Eun, Edwards, Seth D, Guim, Hwanuk, Jae Jeong, Kyung

“…Polyamidoamine (PAMAM) dendrimers have been explored as an alternative to polyethylenimine (PEI) as a gene delivery carrier because of its relatively low…”
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Matrix Metalloproteinase-Deactivating Contact Lens for Corneal Melting by Lopez, Chelsi, Park, Shiwha, Edwards, Seth, Vong, Selina, Hou, Shujie, Lee, Minyoung, Sauerland, Hunter, Lee, Jung-Jae, Jeong, Kyung Jae

“…Corneal melting is an uncontrolled, excessive degradation of cellular and extracellular components of the cornea. This potential cause of corneal blindness is…”
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