Search Results - "Edwards, K. J"

Whole-exome sequencing efficiently detects rare mutations in autosomal recessive nonsyndromic hearing loss by Diaz-Horta, Oscar, Duman, Duygu, Foster, 2nd, Joseph, Sırmacı, Aslı, Gonzalez, Michael, Mahdieh, Nejat, Fotouhi, Nikou, Bonyadi, Mortaza, Cengiz, Filiz Başak, Menendez, Ibis, Ulloa, Rick H, Edwards, Yvonne J K, Züchner, Stephan, Blanton, Susan, Tekin, Mustafa

“…Identification of the pathogenic mutations underlying autosomal recessive nonsyndromic hearing loss (ARNSHL) is difficult, since causative mutations in 39…”
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ASAH1 facilitates TNBC by DUSP5 suppression-driven activation of MAP kinase pathway and represents a therapeutic vulnerability by Reddi, Kiran Kumar, Chava, Suresh, Chabattula, Siva Chander, Edwards, Yvonne J. K., Singh, Kamaljeet, Gupta, Romi

“…Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is prone to metastasis and therapy resistance. Owing to its aggressive nature and…”
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Isolation and Characterization of Novel Psychrophilic, Neutrophilic, Fe-Oxidizing, Chemolithoautotrophic α- and γ-Proteobacteria from the Deep Sea by EDWARDS, K. J, ROGERS, D. R, WIRSEN, C. O, MCCOLLOM, T. M

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Comparative transcriptomics in human COPD reveals dysregulated genes uniquely expressed in ferrets by Hussain, Shah S, Edwards, Yvonne J K, Libby, Emily Falk, Stanford, Denise, Byzek, Stephen A, Sin, Don D, McDonald, Merry-Lynn, Raju, S Vamsee, Rowe, Steven M

“…Chronic obstructive pulmonary disease (COPD) is a progressive lung disease with poor treatment options. However, most mouse models of COPD produce a primarily…”
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Disruptor of telomeric silencing 1-like promotes ovarian cancer tumor growth by stimulating pro-tumorigenic metabolic pathways and blocking apoptosis by Chava, Suresh, Bugide, Suresh, Edwards, Yvonne J. K., Gupta, Romi

“…ABSTRACT Ovarian cancer is the leading cause of gynecological malignancy-related deaths. Current therapies for ovarian cancer do not provide meaningful and…”
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Quantitative trait locus analysis of fungal disease resistance factors on a molecular map of grapevine by FISCHER, B. M, SALAKHUTDINOV, I, AKKURT, M, EIBACH, R, EDWARDS, K. J, TÖPFER, R, ZYPRIAN, E. M

“…A full-sibling F1 population comprising 153 individuals from the cross of ‘Regent’ × ‘Lemberger’ was employed to construct a genetic map based on 429 molecular…”
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Highly conserved non-coding sequences are associated with vertebrate development by Woolfe, Adam, Goodson, Martin, Goode, Debbie K, Snell, Phil, McEwen, Gayle K, Vavouri, Tanya, Smith, Sarah F, North, Phil, Callaway, Heather, Kelly, Krys, Walter, Klaudia, Abnizova, Irina, Gilks, Walter, Edwards, Yvonne J K, Cooke, Julie E, Elgar, Greg

“…In addition to protein coding sequence, the human genome contains a significant amount of regulatory DNA, the identification of which is proving somewhat…”
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A Simple Sequence Repeat-Based Linkage Map of Barley by Ramsay, L, Macaulay, M, degli Ivanissevich, S, MacLean, K, Cardle, L, Fuller, J, Edwards, K. J, Tuvesson, S, Morgante, M, Massari, A, Maestri, E, Marmiroli, N, Sjakste, T, Ganal, M, Powell, W, Waugh, R

“…A total of 568 new simple sequence repeat (SSR)-based markers for barley have been developed from a combination of database sequences and small insert genomic…”
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Spatiotemporal Distribution of Marine Magnetotactic Bacteria in a Seasonally Stratified Coastal Salt Pond by SIMMONS, S. L, SIEVERT, S. M, FRANKEL, R. B, BAZYLINSKI, D. A, EDWARDS, K. J

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Challenges in whole exome sequencing: an example from hereditary deafness by Sirmaci, Asli, Edwards, Yvonne J K, Akay, Hatice, Tekin, Mustafa

“…Whole exome sequencing provides unprecedented opportunities to identify causative DNA variants in rare Mendelian disorders. Finding the responsible mutation…”
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Microsatellite repeats in common bean (Phaseolus vulgaris): Isolation, characterization, and cross-species amplification in Phaseolus ssp by GAITAN-SOLIS, E, DUQUE, M. C, EDWARDS, K. J, TOHME, J

“…ABSTRACT Phaseolus beans are distributed worldwide and are cultivated in the tropics, subtropics, and temperate zones. The common bean is the most important…”
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Whole-Exome Sequencing Links a Variant in DHDDS to Retinitis Pigmentosa by Züchner, Stephan, Dallman, Julia, Wen, Rong, Beecham, Gary, Naj, Adam, Farooq, Amjad, Kohli, Martin A., Whitehead, Patrice L., Hulme, William, Konidari, Ioanna, Edwards, Yvonne J.K., Cai, Guiqing, Peter, Inga, Seo, David, Buxbaum, Joseph D., Haines, Jonathan L., Blanton, Susan, Young, Juan, Alfonso, Eduardo, Vance, Jeffery M., Lam, Byron L., Peričak-Vance, Margaret A.

“…Increasingly, mutations in genes causing Mendelian disease will be supported by individual and small families only; however, exome sequencing studies have thus…”
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Identifying consensus disease pathways in Parkinson's disease using an integrative systems biology approach by Edwards, Yvonne J K, Beecham, Gary W, Scott, William K, Khuri, Sawsan, Bademci, Guney, Tekin, Demet, Martin, Eden R, Jiang, Zhijie, Mash, Deborah C, ffrench-Mullen, Jarlath, Pericak-Vance, Margaret A, Tsinoremas, Nicholas, Vance, Jeffery M

“…Parkinson's disease (PD) has had six genome-wide association studies (GWAS) conducted as well as several gene expression studies. However, only variants in…”
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Comparison of three targeted enrichment strategies on the SOLiD sequencing platform by Hedges, Dale J, Guettouche, Toumy, Yang, Shan, Bademci, Guney, Diaz, Ashley, Andersen, Ashley, Hulme, William F, Linker, Sara, Mehta, Arpit, Edwards, Yvonne J K, Beecham, Gary W, Martin, Eden R, Pericak-Vance, Margaret A, Zuchner, Stephan, Vance, Jeffery M, Gilbert, John R

“…Despite the ever-increasing throughput and steadily decreasing cost of next generation sequencing (NGS), whole genome sequencing of humans is still not a…”
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microsatellite marker based framework linkage map of Vitis vinifera L by RIAZ, S, DANGL, G. S, EDWARDS, I. K. J, MEREDITH, C. P

“…We have constructed a framework linkage map based on microsatellite markers for Vitis vinifera L., the European wine grape. The mapping population consisted of…”
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Microstructural Development and Catalytic Performance of Au−Pd Nanoparticles on Al2O3 Supports: The Effect of Heat Treatment Temperature and Atmosphere by Herzing, A. A, Carley, A. F, Edwards, J. K, Hutchings, G. J, Kiely, C. J

“…Au−Pd nanoparticles supported on a variety of oxides are known to be highly active catalysts for a number of interesting reactions, including the direct…”
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Facial recognition lock technology for social care settings: A qualitative evaluation of implementation of facial recognition locks at two residential care sites by Bradwell, H L, Edwards, K J, Baines, R, Page, T, Chatterjee, A, Jones, R B

“…There is limited literature on security and access for social care settings despite policy highlighting importance, and no published research exploring facial…”
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Characterisation of polymorphic microsatellite markers from Aegilops tauschii and transferability to the D-genome of bread wheat by GUYOMARC'H, H, SOURDILLE, P, CHARMET, G, EDWARDS, K. J, BERNARD, M

“…Microsatellites were isolated from a Aegilops tauschii (the D-genome donor of bread wheat) library enriched for various motifs. Primers generated from the…”
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C-Dead Living Biomass: Evidence for Microbial Assimilation of Ancient Organic Carbon During Shale Weathering by Petsch, S. T, Eglinton, T. I, Edwards, K. J

“…Prokaryotes have been cultured from a modern weathering profile developed on a ~365-million-year-old black shale that use macromolecular shale organic matter…”
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Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma by Venkatesan, Arvind M, Vyas, Rajesh, Gramann, Alec K, Dresser, Karen, Gujja, Sharvari, Bhatnagar, Sanchita, Chhangawala, Sagar, Gomes, Camilla Borges Ferreira, Xi, Hualin Simon, Lian, Christine G, Houvras, Yariv, Edwards, Yvonne J K, Deng, April, Green, Michael, Ceol, Craig J

“…Oncogenomic studies indicate that copy number variation (CNV) alters genes involved in tumor progression; however, identification of specific driver genes…”
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