Search Results - "Edwards, Gwynneth M."

Neural precursor cell chain migration and division are regulated through different β1 integrins by Jacques, Thomas S., B. Relvas, João, Nishimura, Stephen, Pytela, Robert, M. Edwards, Gwynneth, Streuli, Charles H., ffrench-Constant, Charles

“…ABSTRACT Proliferation and tangential migration of neural precursor cells are essential determinants of CNS development. We have established cell culture…”
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Laminin and β1 Integrins Are Crucial for Normal Mammary Gland Development in the Mouse by Klinowska, Teresa C.M., Soriano, Jesus V., Edwards, Gwynneth M., Oliver, Janine M., Valentijn, Anthony J., Montesano, Roberto, Streuli, Charles H.

“…We have examined the role of integrin–extracellular matrix interactions in the morphogenesis of ductal structures in vivo using the developing mouse mammary…”
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Requirement of basement membrane for the suppression of programmed cell death in mammary epithelium by Pullan, S, Wilson, J, Metcalfe, A, Edwards, G M, Goberdhan, N, Tilly, J, Hickman, J A, Dive, C, Streuli, C H

“…Apoptosis is an active mechanism of cell death required for normal tissue homeostasis. Cells require survival signals to avoid the engagement of apoptosis. In…”
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Stat5 as a Target for Regulation by Extracellular Matrix (∗) by Streuli, Charles H., Edwards, Gwynneth M., Delcommenne, Marc, Whitelaw, C. Bruce A., Burdon, Thomas G., Schindler, Chris, Watson, Christine J.

“…Transcription of tissue-specific genes in mammary gland requires signals from both prolactin and basement membrane. Here we address the mechanism by which this…”
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Regulation of Mammary Differentiation by Extracellular Matrix Involves Protein-tyrosine Phosphatases by Edwards, G M, Wilford, F H, Liu, X, Hennighausen, L, Djiane, J, Streuli, C H

“…Extracellular matrix and growth factors cooperate to regulate signaling pathways and gene transcription in adherent cells. However, the mechanism of…”
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Control of normal mammary epithelial phenotype by integrins by Streuli, C H, Edwards, G M

“…Mammary epithelial cells contact a specialized extracellular matrix in vivo known as the basement membrane. Interactions with extracellular matrix are mediated…”
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Extracellular matrix controls the prolactin signalling pathway in mammary epithelial cells by Edwards, G M, Wilford, F H, Streuli, C H

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Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides by QIANJIN HU, BAUTISTA, C, EDWARDS, G. M, DEFEO-JONES, D, JONES, R. E, HARLOW, E

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Transforming Growth Factor α-Pseudomonas Exotoxin Fusion Protein Prolongs Survival of Nude Mice Bearing Tumor Xenografts by Heimbrook, David C., Stirdivant, Steven M., Ahern, Janet D., Balishin, Nancy L., Patrick, Denis R., Edwards, Gwynneth M., Defeo-Jones, Deborah, FitzGerald, David J., Pastan, Ira, Oliff, Allen

“…Transforming growth factor α (TGFα)-Pseudomonas exotoxin 40 (PE40) is a chimeric protein consisting of an N-terminal TGFα domain fused to a C-terminal 40-kDa…”
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Purification and characterization of a functionally homogeneous 60-kDa species of the retinoblastoma gene product by EDWARDS, G. M, HUBER, H. E, HEIMBROOK, D. C, DEFEO-JONES, D, VUOCOLO, G, GOODHART, P. J, MAIGETTER, R. Z, SANYALL, G, SANYAL, G, OLIFF, A

“…The retinoblastoma susceptibility gene (RB) encodes a 928-amino acid protein (pRB) that is hypothesized to function in a pathway that restricts cell…”
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Antibodies Specific for the Human Retinoblastoma Protein Identify a Family of Related Polypeptides by Hu, Qianjin, Bautista, Carmelita, Edwards, Gwynneth M., Defeo-Jones, Deborah, Jones, Raymond E., Harlow, Ed

“…Even though the retinoblastoma gene is one of the best-studied tumor suppressor genes, little is known about its functional role. Like all tumor suppressor…”
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Epidermal Growth Factor Receptor Binding Is Affected by Structural Determinants in the Toxin Domain of Transforming Growth Factor-Alpha-Pseudomonas Exotoxin Fusion Proteins by Edwards, Gwynneth M., Defeo-Jones, Deborah, Tai, Joseph Y., Vuocolo, Gerald A., Patrick, Denis R., Heimbrook, David C., Oliff, Allen

“…TGF-alpha-PE40 is a hybrid protein composed of transforming growth factor-alpha (TGF-alpha) fused to a 40,000-dalton segment of Pseudomonas exotoxin A (PE40)…”
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Biological activity of a transforming growth factor-alpha--Pseudomonas exotoxin fusion protein in vitro and in vivo by Heimbrook, D C, Stirdivant, S M, Ahern, J D, Balishin, N L, Patrick, D R, Edwards, G M, Defeo-Jones, D, FitzGerald, D J, Pastan, I, Oliff, A

“…Transforming growth factor-alpha (TGF alpha)-pseudomonas exotoxin-40 (PE40) is a chimeric protein consisting of an N-terminal TGF alpha domain fused to a…”
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