Search Results - "Edwards, Daniel J."

The Active Form of E6-associated protein (E6AP)/UBE3A Ubiquitin Ligase Is an Oligomer by Ronchi, Virginia P., Klein, Jennifer M., Edwards, Daniel J., Haas, Arthur L.

“…Employing 125I-polyubiquitin chain formation as a functional readout of ligase activity, biochemical and biophysical evidence demonstrates that catalytically…”
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Lyngbyatoxin Biosynthesis:  Sequence of Biosynthetic Gene Cluster and Identification of a Novel Aromatic Prenyltransferase by Edwards, Daniel J, Gerwick, William H

“…The lyngbyatoxins are potent skin irritants produced by Lyngbya majuscula and cause a condition known as “Swimmer's Itch” off Honolulu, HI. Reported is the…”
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Symplocamide A, a Potent Cytotoxin and Chymotrypsin Inhibitor from the Marine Cyanobacterium Symploca sp by Linington, Roger G, Edwards, Daniel J, Shuman, Cynthia F, McPhail, Kerry L, Matainaho, Teatulohi, Gerwick, William H

“…Investigation of a Symploca sp. from Papua New Guinea has led to the isolation of symplocamide A (1), a potent cancer cell cytotoxin, which also inhibits…”
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Convergent Evolution in the Assembly of Polyubiquitin Degradation Signals by the Shigella flexneri IpaH9.8 Ligase by Edwards, Daniel J., Streich, Frederick C., Ronchi, Virginia P., Todaro, Dustin R., Haas, Arthur L.

“…The human pathogen Shigella flexneri subverts host function and defenses by deploying a cohort of effector proteins via a type III secretion system. The IpaH…”
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TFIIIC Binding Sites Function as both Heterochromatin Barriers and Chromatin Insulators in Saccharomyces cerevisiae by Simms, Tiffany A, Dugas, Sandra L, Gremillion, Jason C, Ibos, Megan E, Dandurand, M Nicole, Toliver, Tasha T, Edwards, Daniel J, Donze, David

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Enzymatic Production of (−)-Indolactam V by LtxB, a Cytochrome P450 Monooxygenase by Huynh, Minh U, Elston, Matthew C, Hernandez, Nick M, Ball, David B, Kajiyama, Shin-ichiro, Irie, Kazuhiro, Gerwick, William H, Edwards, Daniel J

“…The P450 cytochrome monooxygenase gene, ltxB, was cloned and overexpressed in Escherichia coli as a 6xHis-tagged protein. The resulting recombinant LtxB was…”
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Assessment of medical students' learning outcomes in Australia : current practice, future possibilities by Wilkinson, David, Canny, Benedict J, Pearce, Jacob V, Coates, Hamish B, Edwards, Daniel J

“…All 19 medical schools in Australia examine and assess the performance of their students, but do so largely in isolation from each other. That is, most schools…”
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Isolation and Characterization of Bacteria that Produce Polyhydroxybutyrate Depolymerases by Egusa, Emily A, Edwards, Daniel J, Thao, MyLo L, Kirk, Larry L, Hanne, Larry F

“…Isolation of environmental bacterial strains with diverse metabolic properties such as antibiotic production, sulfide oxidation, and the ability to use…”
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Liquid hydrogen fuel system design and demonstration in a small long endurance air vehicle by Stroman, Richard O., Schuette, Michael W., Swider-Lyons, Karen, Rodgers, Joseph A., Edwards, Daniel J.

“…Autonomous systems have advanced substantially, yet on-board energy capacity still constrains endurance. Liquid hydrogen (LH2) fuel storage coupled with a high…”
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Activity Screening of Carrier Domains within Nonribosomal Peptide Synthetases Using Complex Substrate Mixtures and Large Molecule Mass Spectrometry by Dorrestein, Pieter C, Blackhall, Jonathan, Straight, Paul D, Fischbach, Michael A, Garneau-Tsodikova, Sylvie, Edwards, Daniel J, McLaughlin, Shaun, Lin, Myat, Gerwick, William H, Kolter, Roberto, Walsh, Christopher T, Kelleher, Neil L

“…For screening a pool of potential substrates that load carrier domains found in nonribosomal peptide synthetases, large molecule mass spectrometry is shown to…”
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Virtual protein purification: A simple exercise to introduce ph as a parameter that effects ion exchange chromatography by Clark, Daniel D., Edwards, Daniel J.

“…This article describes a simple exercise using a free, easy‐to‐use, established online program. The exercise helps to reinforce protein purification concepts…”
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Evaluation of Streptomyces coelicolor A3(2) as a heterologous expression host for the cyanobacterial protein kinase C activator lyngbyatoxin A by Jones, Adam C., Ottilie, Sabine, Eustáquio, Alessandra S., Edwards, Daniel J., Gerwick, Lena, Moore, Bradley S., Gerwick, William H.

“…Filamentous marine cyanobacteria are extremely rich sources of bioactive natural products and often employ highly unusual biosynthetic enzymes in their…”
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Structure and Biosynthesis of the Jamaicamides, New Mixed Polyketide-Peptide Neurotoxins from the Marine Cyanobacterium Lyngbya majuscula by Edwards, Daniel J, Marquez, Brian L, Nogle, Lisa M, McPhail, Kerry, Goeger, Douglas E, Roberts, Mary Ann, Gerwick, William H

“…A screening program for bioactive compounds from marine cyanobacteria led to the isolation of jamaicamides A–C. Jamaicamide A is a novel and highly…”
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Cloning and Characterization of the Bleomycin Biosynthetic Gene Cluster from Streptomyces verticillus ATCC15003 by SHEN, Ben, DU, Liangcheng, SANCHEZ, Cesar, EDWARDS, Daniel J., CHEN, Mei, MURRELL, Jeffrey M.

“…Bleomycin (BLM) biosynthesis has been studied as a model for hybrid peptide-polyketide natural product biosynthesis. Cloning, sequencing, and biochemical…”
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The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase by Du, Liangcheng, Sánchez, César, Chen, Mei, Edwards, Daniel J, Shen, Ben

“…Background: The structural and catalytic similarities between modular nonribosomal peptide synthetases (NRPSs) and polyketide synthases (PKSs) inspired us to…”
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Cloning and characterization of a phosphopantetheinyl transferase from Streptomyces verticillus ATCC15003, the producer of the hybrid peptide–polyketide antitumor drug bleomycin by Sánchez, César, Du, Liangcheng, Edwards, Daniel J, Toney, Michael D, Shen, Ben

“…Background: Phosphopantetheinyl transferases (PPTases) catalyze the posttranslational modification of carrier proteins by the covalent attachment of the…”
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Parental use and misuse of antibiotics: are there differences in urban vs. suburban settings? by Edwards, Daniel J, Richman, Peter B, Bradley, Keith, Eskin, Barnet, Mandell, Mark

“…To compare the frequencies with which suburban and urban parents give their children antibiotics without first consulting a physician. This was a prospective,…”
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Cloning and Characterization of the Bleomycin Biosynthetic Gene Cluster from Streptomyces v erticillus ATCC15003 by Shen, Ben, Du, Liangcheng, Sanchez, Cesar, Edwards, Daniel J, Chen, Mei, Murrell, Jeffrey M

“…Bleomycin (BLM) biosynthesis has been studied as a model for hybrid peptide−polyketide natural product biosynthesis. Cloning, sequencing, and biochemical…”
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A Qualitative Study of the Perceptions of Higher Education Students and Faculty Regarding Student Choice and Student-Centered Learning Approaches in a Radiologic Science Program by Edwards, Daniel J

“…There has been a movement to change the landscape of the higher education classroom from the more traditional method of lecture-centered learning to more…”
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Evaluating the Collective Consideration in the Measurement of Political Efficacy by Edwards, Daniel J

“…Politically oriented collective efficacy has yet to be explored as a unique and distinct construct. Effects of assessments about politically organized…”
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