Search Results - "Edwards, D I"

Guidelines for the control and prevention of meticillin-resistant Staphylococcus aureus (MRSA) in healthcare facilities by Coia, J.E., Duckworth, G.J., Edwards, D.I., Farrington, M., Fry, C., Humphreys, H., Mallaghan, C., Tucker, D.R.

“…Meticillin-resistant Staphylococcus aureus (MRSA) remains endemic in many UK hospitals. Specific guidelines for control and prevention are justified because…”
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Nitroimidazole drugs--action and resistance mechanisms. II. Mechanisms of resistance by Edwards, D I

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In Vitro Activities of Oral β-Lactams at Concentrations Achieved in Humans against Penicillin-Susceptible and -Resistant Pneumococci and Potential to Select Resistance by THORBURN, C. E, KNOTT, S. J, EDWARDS, D. I

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Redox potential and oxygen concentration as factors in the susceptibility of Helicobacter pylori to nitroheterocyclic drugs by Smith, M A, Edwards, D I

“…Metronidazole sensitive (MtzS) and resistant (MtzR) strains of Helicobacter pylori were tested for their sensitivities to eleven nitroheterocyclic drugs of…”
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Journal of Antimicrobial Chemotherapy online: a personal guide by Edwards, D I

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Guidelines for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the UK by Gemmell, Curtis G., Edwards, David I., Fraise, Adam P., Gould, F. Kate, Ridgway, Geoff L., Warren, Rod E.

“…These evidence-based guidelines have been produced after a literature review of the treatment and prophylaxis of methicillin-resistant Staphylococcus aureus…”
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The influence of microaerophilia and anaerobiosis on metronidazole uptake in Helicobacter pylori by Smith, M A, Edwards, D I

“…Resistance of Helicobacter pylori to metronidazole during therapy for gastroduodenal ulcers is claimed to be responsible for failure to eradicate the pathogen…”
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Oxygen scavenging, NADH oxidase and metronidazole resistance in Helicobacter pylori by SMITH, M. A, EDWARDS, D. I

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The interaction of nitroaromatic drugs with aminothiols by Tocher, Joanne H., Edwards, David I.

“…The effect of cysteamine and glutathione addition on the redox behaviour of metronidazole, chloramphenicol, M&B 4998, nitrofurazone, and nifuroxime has been…”
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Susceptibility testing methods: why use the MIC? by Edwards, D I

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Population development of Heterodera glycines and soybean yield in soybean-maize rotations following introduction into a noninfested field by Noel, G R, Edwards, D I

“…An 11-year field study was initiated in 1979 to monitor population development of Heterodera glycines. Fifty cysts of a race 5 population were introduced into…”
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Nitroimidazole drugs--action and resistance mechanisms. I. Mechanisms of action by Edwards, D I

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MRSA behind bars? by Coia, J.E., Duckworth, G., Edwards, D.I., Farrington, M., Humphreys, H., Mallaghan, C., Tucker, D.R.

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Studies on DNA damage and induction of SOS repair by novel multifunctional bioreducible compounds. II. A metronidazole adduct of a ruthenium-arene compound by Dale, L D, Tocher, J H, Dyson, T M, Edwards, D I, Tocher, D A

“…A new transition metal complex of the 5-nitroimidazole, metronidazole (1-beta-hydroxyethyl-2-methyl-5-nitroimidazole), has been prepared and its potential use…”
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DNA damage induced by reduced nitroimidazole drugs by Zahoor, A, Lafleur, M V, Knight, R C, Loman, H, Edwards, D I

“…Five nitroimidazole drugs were reduced electrolytically and by gamma-radiolysis at fast (300 mumoles or 100% per hr) and slow (3-9 mumoles or 1-3% per hr)…”
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Electrochemical studies of tirapazamine: generation of the one-electron reduction product by Tocher, J H, Edwards, D I

“…The electrochemical properties of the benzotriazine di-N-oxide, tirapazamine (SR4233), and the mono- and zero-N-oxides, SR4317 and SR4330 respectively, have…”
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Electrochemical characteristics of nitroheterocyclic compounds of biological interest. V. Measurement and comparison of nitro radical lifetimes by Tocher, J H, Edwards, D I

“…Using mixed aqueous/dimethylformamide solvents we have generated nitro radical anions by electrochemical reduction of nitroaromatic compounds. Six drugs have…”
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The reactivity of chloramphenicol reduction products with DNA bases by Tocher, J H, Edwards, D I, Thomas, A

“…The interaction between the constituent bases of deoxyribonucleic acid and the reduction products of the nitro-aromatic compound chloramphenicol and its…”
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The interaction of reduced metronidazole with DNA bases and nucleosides by Tocher, J H, Edwards, D I

“…The electrochemical behavior of the 1-electron couple for the bioreductive drug metronidazole has been examined in the presence and absence of the biological…”
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Repair of damage induced by SR 4233 by Edwards, D I, Virk, N S

“…The benzotriazine di-N-oxide, SR 4233, was electrolytically reduced at constant potential at pH 4.0 at a reduction rate of 5%/hr under N2 in the presence of…”
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