Search Results - "Edupuganti, Uthama R."
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Diversity of function and higher-order structure within HWE sensor histidine kinases
Published in The Journal of biological chemistry (01-08-2023)“…Integral to the protein structure/function paradigm, oligomeric state is typically conserved along with function across evolution. However, notable exceptions…”
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Insights into histidine kinase activation mechanisms from the monomeric blue light sensor EL346
Published in Proceedings of the National Academy of Sciences - PNAS (12-03-2019)“…Translation of environmental cues into cellular behavior is a necessary process in all forms of life. In bacteria, this process frequently involves…”
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Unraveling the Mechanism of a LOV Domain Optogenetic Sensor: A Glutamine Lever Induces Unfolding of the Jα Helix
Published in ACS chemical biology (16-10-2020)“…Light-activated protein domains provide a convenient, modular, and genetically encodable sensor for optogenetics and optobiology. Although these domains have…”
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