Search Results - "Edupuganti, Raghu Ram"

Higher chromatin mobility supports totipotency and precedes pluripotency in vivo by Bošković, Ana, Eid, André, Pontabry, Julien, Ishiuchi, Takashi, Spiegelhalter, Coralie, Raghu Ram, Edupuganti V S, Meshorer, Eran, Torres-Padilla, Maria-Elena

“…The fusion of the gametes upon fertilization results in the formation of a totipotent cell. Embryonic chromatin is expected to be able to support a large…”
Get full text

ZMYND8 Co-localizes with NuRD on Target Genes and Regulates Poly(ADP-Ribose)-Dependent Recruitment of GATAD2A/NuRD to Sites of DNA Damage by Spruijt, Cornelia G., Luijsterburg, Martijn S., Menafra, Roberta, Lindeboom, Rik G.H., Jansen, Pascal W.T.C., Edupuganti, Raghu Ram, Baltissen, Marijke P., Wiegant, Wouter W., Voelker-Albert, Moritz C., Matarese, Filomena, Mensinga, Anneloes, Poser, Ina, Vos, Harmjan R., Stunnenberg, Hendrik G., van Attikum, Haico, Vermeulen, Michiel

“…NuRD (nucleosome remodeling and histone deacetylase) is a versatile multi-protein complex with roles in transcription regulation and the DNA damage response…”
Get full text

Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation by Alvarez-Saavedra, Matías, De Repentigny, Yves, Lagali, Pamela S., Raghu Ram, Edupuganti V. S., Yan, Keqin, Hashem, Emile, Ivanochko, Danton, Huh, Michael S., Yang, Doo, Mears, Alan J., Todd, Matthew A. M., Corcoran, Chelsea P., Bassett, Erin A., Tokarew, Nicholas J. A., Kokavec, Juraj, Majumder, Romit, Ioshikhes, Ilya, Wallace, Valerie A., Kothary, Rashmi, Meshorer, Eran, Stopka, Tomas, Skoultchi, Arthur I., Picketts, David J.

“…Chromatin compaction mediates progenitor to post-mitotic cell transitions and modulates gene expression programs, yet the mechanisms are poorly defined. Snf2h…”
Get full text

Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells by Mattout, Anna, Aaronson, Yair, Sailaja, Badi Sri, Raghu Ram, Edupuganti V, Harikumar, Arigela, Mallm, Jan-Philipp, Sim, Kae Hwan, Nissim-Rafinia, Malka, Supper, Emmanuelle, Singh, Prim B, Sze, Siu Kwan, Gasser, Susan M, Rippe, Karsten, Meshorer, Eran

“…Pluripotent embryonic stem cells (ESCs) have the unique ability to differentiate into every cell type and to self-renew. These characteristics correlate with a…”
Get full text

Nuclear-encoded DnaJ homologue of Plasmodium falciparum interacts with replication ori of the apicoplast genome by Kumar, Ambrish, Tanveer, Aiman, Biswas, Subir, Ram, Edupuganti V.S. Raghu, Gupta, Ankit, Kumar, Bijay, Habib, Saman

“…The apicoplast of Plasmodium falciparum carries a 35 kb circular genome (plDNA) that replicates at the late trophozoite stage of the parasite intraerythocytic…”
Get full text

Transcriptional competence in pluripotency by Ram, Edupuganti V S Raghu, Meshorer, Eran

“…Embryonic stem (ES) cells possess a globally open, decondensed chromatin structure that, together with trans-acting factors, supports transcriptional…”
Get full text

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131 by Varier, Radhika A., de Santa Pau, Enrique Carrillo, van der Groep, Petra, Lindeboom, Rik G.H., Matarese, Filomena, Mensinga, Anneloes, Smits, Arne H., Edupuganti, Raghu Ram, Baltissen, Marijke P., Jansen, Pascal W.T.C., ter Hoeve, Natalie, van Weely, Danny R., Poser, Ina, van Diest, Paul J., Stunnenberg, Hendrik G., Vermeulen, Michiel

“…Recent work from others and us revealed interactions between the Sin3/HDAC complex, the H3K4me3 demethylase KDM5A, GATAD1, and EMSY. Here, we characterize the…”
Get full text

An Endogenously Tagged Fluorescent Fusion Protein Library in Mouse Embryonic Stem Cells by Harikumar, Arigela, Edupuganti, Raghu Ram, Sorek, Matan, Azad, Gajendra Kumar, Markoulaki, Styliani, Sehnalová, Petra, Legartová, Soňa, Bártová, Eva, Farkash-Amar, Shlomit, Jaenisch, Rudolf, Alon, Uri, Meshorer, Eran

“…Embryonic stem cells (ESCs), with their dual capacity to self-renew and differentiate, are commonly used to study differentiation, epigenetic regulation,…”
Get full text

Alternative SET/TAFI Promoters Regulate Embryonic Stem Cell Differentiation by Edupuganti, Raghu Ram, Harikumar, Arigela, Aaronson, Yair, Biran, Alva, Sailaja, Badi Sri, Nissim-Rafinia, Malka, Azad, Gajendra Kumar, Cohen, Malkiel A., Park, Jung Eun, Shivalila, Chikdu S., Markoulaki, Styliani, Sze, Siu Kwan, Jaenisch, Rudolf, Meshorer, Eran

“…Embryonic stem cells (ESCs) are regulated by pluripotency-related transcription factors in concert with chromatin regulators. To identify additional stem cell…”
Get full text

Transcriptional competence in pluripotency: Figure 1 by Raghu Ram, Edupuganti V.S., Meshorer, Eran

“…Embryonic stem (ES) cells possess a globally open, decondensed chromatin structure that, together with trans -acting factors, supports transcriptional…”
Get full text

Neuronal differentiation requires BRAT1 complex to remove REST from chromatin by Dokaneheifard, Sadat, Gomes Dos Santos, Helena, Guiselle Valencia, Monica, Arigela, Harikumar, Edupuganti, Raghu Ram, Shiekhattar, Ramin

“…Repressor element-1 silencing transcription factor (REST) is required for the formation of mature neurons. REST dysregulation underlies a key mechanism of…”
Get full text

Integrator enforces the fidelity of transcriptional termination at protein-coding genes by Dasilva, Lucas Ferreira, Blumenthal, Ezra, Beckedorff, Felipe, Cingaram, Pradeep Reddy, Gomes Dos Santos, Helena, Edupuganti, Raghu Ram, Zhang, Anda, Dokaneheifard, Sadat, Aoi, Yuki, Yue, Jingyin, Kirstein, Nina, Tayari, Mina Masoumeh, Shilatifard, Ali, Shiekhattar, Ramin

“…Integrator regulates the 3′-end processing and termination of multiple classes of noncoding RNAs. Depletion of INTS11, the catalytic subunit of Integrator, or…”
Get full text