Search Results - "Edueng, Khadijah"

The Need for Restructuring the Disordered Science of Amorphous Drug Formulations by Edueng, Khadijah, Mahlin, Denny, Bergström, Christel A. S.

“…The alarming numbers of poorly soluble discovery compounds have centered the efforts towards finding strategies to improve the solubility. One of the…”
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Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage by Edueng, Khadijah, Mahlin, Denny, Gråsjö, Johan, Nylander, Olivia, Thakrani, Manish, Bergström, Christel A S

“…This study explores the effect of physical aging and/or crystallization on the supersaturation potential and crystallization kinetics of amorphous active…”
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Long-Term Physical (In)Stability of Spray-Dried Amorphous Drugs: Relationship with Glass-Forming Ability and Physicochemical Properties by Edueng, Khadijah, Bergström, Christel A S, Gråsjö, Johan, Mahlin, Denny

“…This study shows the importance of the chosen method for assessing the glass-forming ability (GFA) and glass stability (GS) of a drug compound. Traditionally,…”
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Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into crystallization pathways by Edueng, Khadijah, Mahlin, Denny, Larsson, Per, Bergström, Christel A.S.

“…We developed a step-by-step experimental protocol using differential scanning calorimetry (DSC), dynamic vapour sorption (DVS), polarized light microscopy…”
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Pharmaceutical profiling and molecular dynamics simulations reveal crystallization effects in amorphous formulations by Edueng, Khadijah, Kabedev, Aleksei, Ekdahl, Alyssa, Mahlin, Denny, Baumann, John, Mudie, Deanna, Bergström, Christel A.S.

“…[Display omitted] Robust and reliable in vivo performance of medicines based on amorphous solid dispersions (ASDs) depend on maintenance of physical stability…”
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An in vitro dissolution–digestion–permeation assay for the study of advanced drug delivery systems by Alvebratt, Caroline, Keemink, Janneke, Edueng, Khadijah, Cheung, Ocean, Strømme, Maria, Bergström, Christel A.S.

“…[Display omitted] Advanced drug delivery systems (ADDS) are widely explored to overcome poor aqueous solubility of orally administered drugs. However, the…”
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Benefits of combining supersaturating and solubilizing formulations – Is two better than one? by Alvebratt, Caroline, Karlén, Filip, Åhlén, Michelle, Edueng, Khadijah, Dubbelboer, Ilse, Bergström, Christel A.S.

“…[Display omitted] •An LBF and an ASD were studied, separate and in combination.•A combined dissolution-/digestion-absorption assay was used in vitro.•In vivo…”
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Palm Olein Emulsion: a Novel Vehicle for Topical Drug Delivery of Betamethasone 17-Valerate by Ahmad, Kausar, Win, Thazin, Jaffri, Juliana Md, Edueng, Khadijah, Taher, Muhammad

“…This study aims to investigate the use of palm olein as the oil phase for betamethasone 17-valerate (BV) emulsions. The physicochemical properties of the…”
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Interlaboratory Validation of Small-Scale Solubility and Dissolution Measurements of Poorly Water-Soluble Drugs by Andersson, Sara B E, Alvebratt, Caroline, Bevernage, Jan, Bonneau, Damien, da Costa Mathews, Claudia, Dattani, Rikesh, Edueng, Khadijah, He, Yan, Holm, René, Madsen, Cecilie, Müller, Thomas, Muenster, Uwe, Müllertz, Anette, Ojala, Krista, Rades, Thomas, Sieger, Peter, Bergström, Christel A S

“…The purpose of this study was to investigate the interlaboratory variability in determination of apparent solubility (Sapp) and intrinsic dissolution rate…”
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Haplophytin B from Maclurodendron porteri by Taher, Muhammad, Susanti, Deny, Abd Hamid, Shafida, Edueng, Khadijah, Jaffri, Juliana Md, Adina, Anugerah Budipratama, Rezali, Mohamad Fazlin

“…An alkaloid from Maclurodendron porteri has been isolated and characterized. Extraction process was conducted by acid-base extraction method followed by column…”
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