Search Results - "Eduardo Pentón-Arias"

Phycocyanobilin reduces brain injury after endothelin‐1‐ induced focal cerebral ischaemia by Pavón‐Fuentes, Nancy, Marín‐Prida, Javier, Llópiz‐Arzuaga, Alexey, Falcón‐Cama, Viviana, Campos‐Mojena, Rosario, Cervantes‐Llanos, Majel, Piniella‐Matamoros, Beatriz, Pentón‐Arias, Eduardo, Pentón‐Rol, Giselle

“…Pharmacological therapies for interrupting biochemical events of the ischaemic cascade and protecting against stroke in humans are as yet unavailable. Up to…”
Get full text

Preparing for the Next Pandemic: Increased Expression of Interferon-Stimulated Genes After Local Administration of Nasalferon or HeberNasvac by Aguiar Santiago, Jorge Agustín, Marrero Miragaya, Maria Acelia, Figueroa Oliva, Dariel Adrian, Aguilar Juanes, Andres, Idavoy Corona, Arletis, Martínez Fernández, Seknia, Morán Bertot, Ivis, Rodríguez Hernández, Meilyn, Canales López, Eduardo, Hernández Esteves, Ingrid, Silva Girado, José Angel, Estrada Vázquez, Regla Caridad, Gell Cuesta, Omar, Mendoza-Marí, Yssel, Valdés Prado, Iris, Rodríguez Ibarra, Chabeli, Palenzuela Gardon, Daniel Octavio, Pentón Arias, Eduardo, Guillén Nieto, Gerardo, Aguilar Rubido, Julio Cesar

“…HeberNasvac, a therapeutic vaccine for chronic hepatitis B, is able to safely stimulate multiple Toll-like receptors, increasing antigen presentation and in a…”
Get more information

Anti-inflammatory mechanisms and pharmacological actions of phycocyanobilin in a mouse model of experimental autoimmune encephalomyelitis: A therapeutic promise for multiple sclerosis by Marín-Prida, Javier, Pavón-Fuentes, Nancy, Lagumersindez-Denis, Nielsen, Camacho-Rodríguez, Hanlet, García-Soca, Ana Margarita, Sarduy-Chávez, Rocío de la Caridad, Vieira, Érica Leandro Marciano, Carvalho-Tavares, Juliana, Falcón-Cama, Viviana, Fernández-Massó, Julio Raúl, Hernández-González, Ignacio, Martínez-Donato, Gillian, Guillén-Nieto, Gerardo, Pentón-Arias, Eduardo, Teixeira, Mauro Martins, Pentón-Rol, Giselle

“…Cytokines, demyelination and neuroaxonal degeneration in the central nervous system are pivotal elements implicated in the pathogenesis of multiple sclerosis…”
Get full text

The effects of Phycocyanobilin on experimental arthritis involve the reduction in nociception and synovial neutrophil infiltration, inhibition of cytokine production, and modulation of the neuronal proteome by Marín-Prida, Javier, Rodríguez-Ulloa, Arielis, Besada, Vladimir, Llopiz-Arzuaga, Alexey, Batista, Nathália Vieira, Hernández-González, Ignacio, Pavón-Fuentes, Nancy, Marciano Vieira, Érica Leandro, Falcón-Cama, Viviana, Acosta, Emilio F., Martínez-Donato, Gillian, Cervantes-Llanos, Majel, Lingfeng, Dai, González, Luis J., Fernández-Massó, Julio Raúl, Guillén-Nieto, Gerardo, Pentón-Arias, Eduardo, Amaral, Flávio Almeida, Teixeira, Mauro Martins, Pentón-Rol, Giselle

“…Introduction The antinociceptive and pharmacological activities of C-Phycocyanin (C-PC) and Phycocyanobilin (PCB) in the context of inflammatory arthritis…”
Get full text

Cuban Prophylactic and Therapeutic Vaccines for Controlling Hepatitis B by Pentón-Arias, Eduardo, Aguilar-Rubido, Julio César

“…Hepatitis B causes liver failure, cirrhosis and cancer. It has an estimated global prevalence of 6%, and 700,000 to 1 million persons die every year of…”
Get full text

Innate Immune Stimulation Should not be Overlooked in Post-exposure Prophylaxis and Early Therapy for Coronavirus Infections by Aguilar-Rubido, Julio C, Pentón-Arias, Eduardo, Akbar, Sheikh Mohammad Fazle

“…We discuss the suitability of innate immune stimulation in acute respiratory infection post-exposure prophylaxis. The induction of innate immunity can be used…”
Get full text

Beneficial effects of oral administration of C-Phycocyanin and Phycocyanobilin in rodent models of experimental autoimmune encephalomyelitis by Cervantes-Llanos, Majel, Lagumersindez-Denis, Nielsen, Marín-Prida, Javier, Pavón-Fuentes, Nancy, Falcon-Cama, Viviana, Piniella-Matamoros, Beatriz, Camacho-Rodríguez, Hanlet, Fernández-Massó, Julio Raúl, Valenzuela-Silva, Carmen, Raíces-Cruz, Ivette, Pentón-Arias, Eduardo, Teixeira, Mauro Martins, Pentón-Rol, Giselle

“…The only three oral treatments currently available for multiple sclerosis (MS) target the relapsing forms of the disease and concerns regarding efficacy,…”
Get full text

The microglial NLRP3 inflammasome is involved in human SARS-CoV-2 cerebral pathogenicity: A report of three post-mortem cases by Cama, Viviana Falcón, Marín-Prida, Javier, Acosta-Rivero, Nelson, Acosta, Emilio F., Díaz, Leonardo Oramas, Casadesús, Ana V., Fernández-Marrero, Briandy, Gilva-Rodríguez, Nathalie, Cremata-García, Daina, Cervantes-Llanos, Majel, Piniella-Matamoros, Beatriz, Sánchez, Daisy, del Rosario-Cruz, Leticia, Borrajero, Israel, Díaz, Angelina, González, Yorexis, Pentón-Arias, Eduardo, Montero-González, Teresita, Guillen-Nieto, Gerardo, Pentón-Rol, Giselle

“…We herein report, by using confocal immunofluorescence, the colocalization of the SARS-CoV-2 nucleocapsid within neurons, astrocytes, oligodendrocytes and…”
Get full text

Phycocyanobilin promotes PC12 cell survival and modulates immune and inflammatory genes and oxidative stress markers in acute cerebral hypoperfusion in rats by Marín-Prida, Javier, Pavón-Fuentes, Nancy, Llópiz-Arzuaga, Alexey, Fernández-Massó, Julio R., Delgado-Roche, Liván, Mendoza-Marí, Yssel, Santana, Seydi Pedroso, Cruz-Ramírez, Alieski, Valenzuela-Silva, Carmen, Nazábal-Gálvez, Marcelo, Cintado-Benítez, Alberto, Pardo-Andreu, Gilberto L., Polentarutti, Nadia, Riva, Federica, Pentón-Arias, Eduardo, Pentón-Rol, Giselle

“…Since the inflammatory response and oxidative stress are involved in the stroke cascade, we evaluated here the effects of Phycocyanobilin (PCB, the…”
Get full text

C-Phycocyanin is neuroprotective against global cerebral ischemia/reperfusion injury in gerbils by Pentón-Rol, Giselle, Marín-Prida, Javier, Pardo-Andreu, Gilberto, Martínez-Sánchez, Gregorio, Acosta-Medina, Emilio Felino, Valdivia-Acosta, Alain, Lagumersindez-Denis, Nielsen, Rodríguez-Jiménez, Efraín, Llópiz-Arzuaga, Alexey, López-Saura, Pedro Antonio, Guillén-Nieto, Gerardo, Pentón-Arias, Eduardo

“…Highlights ► C-Phycocyanin (C-PC) prevents gerbil brain ischemia–reperfusion injury (IRI). ► C-PC reduces infarct volume and hippocampal cell death induced by…”
Get full text

Comparative Neuroregenerative Effects of C-Phycocyanin and IFN-Beta in a Model of Multiple Sclerosis in Mice by Pentón-Rol, Giselle, Lagumersindez-Denis, Nielsen, Muzio, Luca, Bergami, Alessandra, Furlan, Roberto, Fernández-Massó, Julio R., Nazabal-Galvez, Marcelo, Llópiz-Arzuaga, Alexey, Herrera-Rolo, Tania, Veliz-Rodriguez, Tania, Polentarutti, Nadia, Marín-Prida, Javier, Raíces-Cruz, Ivette, Valenzuela-Silva, Carmen, Teixeira, Mauro Martins, Pentón-Arias, Eduardo

“…Multiple Sclerosis (MS) therapies approved so far are unable to effectively reverse the chronic phase of the disease or improve the remyelination process. Here…”
Get full text

C-Phycocyanin protects SH-SY5Y cells from oxidative injury, rat retina from transient ischemia and rat brain mitochondria from Ca2+ /phosphate-induced impairment by Marín-Prida, Javier, Pentón-Rol, Giselle, Rodrigues, Fernando Postalli, Alberici, Luciane Carla, Stringhetta, Karina, Leopoldino, Andréia Machado, Naal, Zeki, Polizello, Ana Cristina Morseli, Llópiz-Arzuaga, Alexey, Rosa, Marcela Nunes, Liberato, José Luiz, Santos, Wagner Ferreira dos, Uyemura, Sergio Akira, Pentón-Arias, Eduardo, Curti, Carlos, Pardo-Andreu, Gilberto L

“…Highlights ► C-Phycocyanin (C-PC) prevented tert -butylhydroperoxide injury in SH-SY5Y cells. ► C-PC protected the retina against elevated intraocular…”
Get full text

C-Phycocyanin ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells by Pentón-Rol, Giselle, Martínez-Sánchez, Gregorio, Cervantes-Llanos, Majel, Lagumersindez-Denis, Nielsen, Acosta-Medina, Emilio Felino, Falcón-Cama, Viviana, Alonso-Ramírez, Ruby, Valenzuela-Silva, Carmen, Rodríguez-Jiménez, Efraín, Llópiz-Arzuaga, Alexey, Marín-Prida, Javier, López-Saura, Pedro Antonio, Guillén-Nieto, Gerardo Emilio, Pentón-Arias, Eduardo

“…For decades Experimental Autoimmune Encephalitis (EAE) has remained as an unsurpassed multiple sclerosis (MS) animal model. C-Phycocyanin (C-Pc) has been…”
Get full text

Innate Immune Stimulation Should not be Overlooked in Postexposure Prophylaxis and Early Therapy for Coronavirus Infections by Aguilar-Rubido, Julio C., Pentón-Arias, Eduardo, Akbar, Sheikh Mohammad Fazle

“…Abstract We discuss the suitability of innate immune stimulation in acute respiratory infection post-exposure prophylaxis. The induction of innate immunity can…”
Get full text

On the Comparison of Two HBV Recombinant Vaccines by Estévez, Zurina Cinza, Silva, Carmen Valenzuela, Arias, Eduardo Pentón

Get full text

Immunogenicity and safety assessment of the Cuban recombinant hepatitis B vaccine in healthy adults by Estévez, Zurina Cinza, Betancourt, Arístides Aguilar, González, Verena Muzio, Baile, Nelvis Figueroa, Silva, Carmen Valenzuela, Bernal, Francisco Hernández, Arias, Eduardo Pentón, Fernández, Aurora Delhanty, Olazábal, Nelia Martin, Amaurys del Río Martín, Batista, Lester Leal, Ríos, Gloria Véliz, Hernández, Héctor Hernández, Hernández, Aracelis Blanco, Lugo, Evelyn Pérez, Joel de la Torre Cruz, Batista Marchec, Bertha L., Leovaldo Álvarez Falcón, Brito, Jannet Trujillo, León, Darién Ortega, Saura, Pedro López

“…Manufactures of biotechnological/biological products (including vaccines) frequently make changes to manufacturing processes of products both during…”
Get full text

Seguridad e inmunogenicidad de la vacuna cubana heberbiovac hb en poblaciones de América, Europa, África y Asia by Victoria Ramírez Albajés, Antonio González Griego, Alina Alerm González, Irma Vega García, Eduardo Pentón Arias, Martha González Griego

“…Se evaluaron la reactogenicidad e inmunogenicidad de la vacuna cubana antihepatitis B (Heberbiovac HB) en 2 942 adultos y 804 niños de diferentes países…”
Get full text

Boosting controlled autoimmunity: a new therapeutic target for CNS disorders by del Barco, Diana García, Berlanga, Jorge, Penton, Eduardo, Hardiman, Orla, Montero, Enrique

“…In most tissues, the immune system plays an essential role in protection, repair and healing. Although immunologically privileged, the CNS remains subject to a…”
Get more information

Generation of a murine model of chronic progressive Experimental Autoimmune Encephalomyelitis for molecular pharmacology studies in Multiple Sclerosis by Karelia Macías-Cosme, Majel Cervantes-Llanos, Javier Marín-Prida, Viviana Falcón-Cama, Eduardo Pentón-Arias, Giselle Pentón-Rol

“…Experimental autoimmune encephalomyelitis (EAE), when induced in syngenic C57BL/6 mice by using myelin oligodendrocyte glycoprotein (MOG), usually exhibits a…”
Get full text