Search Results - "Eduardo Melani Rocha"

Enhancing and sustaining the topical ocular delivery of fluconazole using chitosan solution and poloxamer/chitosan in situ forming gel by Gratieri, Taís, Gelfuso, Guilherme Martins, de Freitas, Osvaldo, Rocha, Eduardo Melani, Lopez, Renata F.V.

“…FLU aqueous humor concentrations assessed by microdialysis in rabbits after the topical administration of the following: (i) poloxamer/chitosan in situ forming…”
Get full text

Dry Eye Disease Treatment: A Systematic Review of Published Trials and a Critical Appraisal of Therapeutic Strategies by Alves, Monica, MD, PhD, Fonseca, Ellen Carrara, MD, Alves, Milena Freitas, MD, Malki, Leonardo Tannus, MD, Arruda, Gustavo Viani, MD, Reinach, Peter S., PhD, Rocha, Eduardo Melani, MD, PhD

“…Abstract Dry eye disease (DED) treatment is an area of increasing complexity, with the emergence of several new treatment agents in recent years. Evaluation of…”
Get full text

Conjunctival Autograft Alone or Combined With Adjuvant Beta-Radiation? A Randomized Clinical Trial by Viani, Gustavo Arruda, M.D, Fonseca, Ellen Carrara, M.D, De Fendi, Ligia Issa, M.D, Rocha, Eduardo Melani, Ph.D., M.D

“…Purpose To evaluate the effectiveness and safety of postoperative low single-dose of beta-irradiation (β-RT) in pterygium comparing conjunctival autograft…”
Get full text

A poloxamer/chitosan in situ forming gel with prolonged retention time for ocular delivery by Gratieri, Taís, Gelfuso, Guilherme Martins, Rocha, Eduardo Melani, Sarmento, Victor Hugo, de Freitas, Osvaldo, Lopez, Renata Fonseca Vianna

“…The aim of the present work was to obtain an ophthalmic delivery system with improved mechanical and mucoadhesive properties that could provide prolonged…”
Get full text

Ocular findings among patients surviving COVID-19 by Costa, Ílen Ferreira, Bonifácio, Livia Pimenta, Bellissimo-Rodrigues, Fernando, Rocha, Eduardo Melani, Jorge, Rodrigo, Bollela, Valdes Roberto, Antunes-Foschini, Rosalia

“…To describe the medium-term ophthalmological findings in patients recovering from COVID-19. Patients recovered from the acute phase of COVID-19 underwent a…”
Get full text

Orofacial Motor Functions and Temporomandibular Disorders in Patients With Sjögren's Syndrome by Zanin, Mariana Cristina, Garcia, Denny Marcos, Rocha, Eduardo Melani, Felício, Cláudia Maria

“…Objective Sjögren's syndrome (SS) induces difficulty in chewing and swallowing due to low salivary flow. However, these symptoms may be associated with other…”
Get full text

Comparison of diagnostic tests in distinct well-defined conditions related to dry eye disease by Alves, Monica, Reinach, Peter Sol, Paula, Jayter Silva, Vellasco e Cruz, Antonio Augusto, Bachette, Leticia, Faustino, Jacqueline, Aranha, Francisco Penteado, Vigorito, Afonso, de Souza, Carmino Antonio, Rocha, Eduardo Melani

“…This study compares signs, symptoms and predictive tools used to diagnose dry eye disease (DED) and ocular surface disorders in six systemic well-defined and…”
Get full text

Sjögren’s disease, occupational performance and quality of life by Carneiro Cintra, Beatriz, Marzola, Mateus Maia, Dakuzaku Carretta, Regina Yoneko, Reis Oliveira, Fabíola, Melani Rocha, Eduardo

Get full text

Is Sjögren's syndrome dry eye similar to dry eye caused by other etiologies? Discriminating different diseases by dry eye tests by Garcia, Denny Marcos, Reis de Oliveira, Fabiola, Módulo, Carolina Maria, Faustino, Jacqueline, Barbosa, Amanda Pires, Alves, Monica, Rocha, Eduardo Melani

“…Dry Eye Disease (DED) is part of several conditions, including Sjögren's syndrome (SS) and no single test to diagnosis DED. The present study intends to…”
Get full text

Characterization of ectopic germinal centers in Sjögren's syndrome (SS) and non‐SS non‐sicca patients by Silva, Evânio Vilela, de Andrade, Bruno Augusto Benevenuto, Silveira, Heitor Albergoni, Rocha, Eduardo Melani, Chahud, Fernando, Brunaldi, Mariângela Ottoboni, Bufalino, Andreia, León, Jorge Esquiche

Get full text

Neurological and Inflammatory Manifestations in Sjögren's Syndrome: The Role of the Kynurenine Metabolic Pathway by de Oliveira, Fabíola Reis, Fantucci, Marina Zilio, Adriano, Leidiane, Valim, Valéria, Cunha, Thiago Mattar, Louzada-Junior, Paulo, Rocha, Eduardo Melani

“…For decades, neurological, psychological, and cognitive alterations, as well as other glandular manifestations (EGM), have been described and are being…”
Get full text

Natural history and predictors for progression in pediatric keratoconus by Antunes-Foschini, Rosalia, Doná, Henrique, de Mello, Pedro Henrique Sant’Anna, Pereira, Renato Bredariol, Marqueis, Isadora Mendes, Rocha, Eduardo Melani, de Faria-e-Sousa, Sidney Julio, Perdona, Gleici Castro

“…We studied the demographic and clinical predictors associated with keratoconus progression in a pediatric population. Retrospective cohort study. We evaluated…”
Get full text

Distinct Inflammatory and Oxidative Effects of Diabetes Mellitus and Hypothyroidism in the Lacrimal Functional Unit by Faustino-Barros, Jacqueline Ferreira, Saranzo Sant'Ana, Ariane Mirela, Dias, Lara Cristina, de Andrade Batista Murashima, Adriana, Costa Mendes da Silva, Lilian Eslaine, Fantucci, Marina Zílio, Garcia, Denny Marcos, Rocha, Eduardo Melani

“…Diabetes mellitus (DM) and hypothyroidism (HT) are prevalent diseases associated with dry eye (DE). Their impact on the lacrimal functional unit (LFU) is…”
Get full text

Multicenter prospective validation study for international chronic ocular graft-versus-host disease consensus diagnostic criteria by Ogawa, Yoko, Dana, Reza, Kim, Stella, Jain, Sandeep, Rosenblatt, Mark I., Perez, Victor L., Clayton, Janine A., Alves, Monica, Rocha, Eduardo Melani, Amparo, Francisco, Seo, Kyoung Yul, Wang, Yan, Shen, Joanne, Oh, Joo Youn, Vanathi, Murugesan, Nair, Sridevi, Na, Kyung-Sun, Riemens, Anjo, Sippel, Kimberly, Soifer, Matias, Wang, Shudan, Trindade, Marilia, Kim, Mee Kum, Yoon, Chang Ho, Yagi, Ryuichiro, Hiratsuka, Ryo, Ogawa, Mamoru, Shimizu, Eisuke, Sato, Yasunori, Pflugfelder, Stephen, Tsubota, Kazuo

“…To validate the international chronic ocular graft-versus-host disease (GVHD) diagnostic criteria (ICCGVHD) compared to the National Institute of Health…”
Get full text

Clinical and laboratory evaluation of sicca complaints: distinctive aspects of primary, secondary and non-Sjogren syndrome by de Oliveira, Fabíola Reis, Motta, Ana Carolina F., Módulo, Carolina Maria, Garcia, Denny Marcos, Chiorini, John A., Louzada-Junior, Paulo, Rocha, Eduardo Melani

“…BACKGROUNDSjögren Syndrome (SS) is a systemic autoimmune disease with a wide spectrum of manifestations that can lead to misdiagnosis. This study describes and…”
Get full text

Assessment of minerals in biological fluids in people with obesity: A pilot study by Junqueira, Gizela Pedroso, Junqueira-Franco, Márcia Varella Morandi, Martin, Rocio San, Brandão, Camila Fernanda Cunha, Júnior, Fernando Barbosa, Rocha, Eduardo Melani, Chueire, Fernando Bahdur, Marchini, Julio Sergio

“…•People with obesity have reduced plasma Se and Fe values.•Salivary Ca and erythrocyte Mg have higher concentrations in people with obesity.•People with…”
Get full text

Oxidative Stress in the Protection and Injury of the Lacrimal Gland and the Ocular Surface: are There Perspectives for Therapeutics? by Lemos, Camila Nunes, da Silva, Lilian Eslaine Costa Mendes, Faustino, Jacqueline Ferreira, Fantucci, Marina Zilio, Murashima, Adriana de Andrade Batista, Adriano, Leidiane, Alves, Monica, Rocha, Eduardo Melani

“…Oxidative stress (OS) is a major disruption in the physiology of the lacrimal functional unit (LFU). Antioxidant enzymes have dual protective activities:…”
Get full text

Are iris mammillations correlated with keratoconus? by Antunes-Foschini, Rosalia M S, Costa, Roberta Martins S, Faria-E-Sousa, Sidney Júlio, Rocha, Eduardo Melani

“…To describe the presence of iris mammillations (IM) in keratoconus. Retrospective case series and literature review. This is a retrospective case series of…”
Get full text

A new method to predict the epidemiology of fungal keratitis by monitoring the sales distribution of antifungal eye drops in Brazil by Ibrahim, Marlon Moraes, de Angelis, Rafael, Lima, Acacio Souza, Viana de Carvalho, Glauco Dreyer, Ibrahim, Fuad Moraes, Malki, Leonardo Tannus, de Paula Bichuete, Marina, de Paula Martins, Wellington, Rocha, Eduardo Melani

“…Fungi are a major cause of keratitis, although few medications are licensed for their treatment. The aim of this study is to observe the variation in…”
Get full text

Dry Eye in Childhood: Epidemiological and Clinical Aspects by Alves, Monica, MD, PhD, Dias, Ana Carolina, MSc, Rocha, Eduardo Melani, MD, PhD

“…Abstract Because dry eye disease is rare in children and its pathogenesis is less well known than in adults, its diagnosis is often overlooked. It can occur in…”
Get full text