Search Results - "Eduardo Krieger, José"

Body mass index is superior to other body adiposity indexes in predicting incident hypertension in a highly admixed sample after 10‐year follow‐up: The Baependi Heart Study by Maciel de Oliveira, Camila, França da Rosa, Francielle, Oliveira Alvim, Rafael, Mourão Junior, Carlos Alberto, Bacells, Mercedes, Liu, Chunyu, Pavani, Jessica, Capasso, Robson, Lavezzo Dias, Fernando Augusto, Eduardo Krieger, José, Costa Pereira, Alexandre

“…Hypertension is the leading cause of overall mortality in low‐ and middle‐income countries. In Brazil, there is paucity of data on the determinants of incident…”
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Biased Agonist TRV027 Determinants in AT1R by Molecular Dynamics Simulations by Modestia, Silvestre Massimo, Malta de Sá, Matheus, Auger, Eric, Trossini, Gustavo Henrique Goulart, Krieger, José Eduardo, Rangel-Yagui, Carlota de Oliveira

“…Functional selectivity is a phenomenon observed in G protein-coupled receptors in which intermediate active-state conformations are stabilized by mutations or…”
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Survival analysis of patients with heart failure: implications of time-varying regression effects in modeling mortality by Giolo, Suely Ruiz, Krieger, José Eduardo, Mansur, Alfredo José, Pereira, Alexandre Costa

“…Several models have been designed to predict survival of patients with heart failure. These, while available and widely used for both stratifying and deciding…”
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Phosphoproteomics Profiling Suggests a Role for Nuclear βΙPKC in Transcription Processes of Undifferentiated Murine Embryonic Stem Cells by Costa-Junior, Helio Miranda, Garavello, Nicole Milaré, Duarte, Mariana Lemos, Berti, Denise Aparecida, Glaser, Talita, Andrade, Alexander de, Labate, Carlos A., Ferreira, André Teixeira da Silva, Perales, Jonas Enrique Aguilar, Xavier-Neto, José, Krieger, José Eduardo, Schechtman, Deborah

“…Protein kinase C (PKC) plays a key role in embryonic stem cell (ESC) proliferation, self-renewal, and differentiation. However, the function of specific PKC…”
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Knockdown of E2f1 by RNA interference impairs proliferation of rat cells in vitro by Dos Reis Vasques, Luciana, Pujiz, Regiane Simoni, Strauss, Bryan Eric, Krieger, José Eduardo

“…E2F1 plays a key role in cell-cycle regulation in mammals, since its transcription factor activity controls genes required for DNA synthesis and apoptosis…”
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Comparing different metabolic indexes to predict type 2 diabetes mellitus in a five years follow-up cohort: The Baependi Heart Study by de Oliveira, Camila Maciel, Pavani, Jessica Leticia, Liu, Chunyu, Balcells, Mercedes, Capasso, Robson, Alvim, Rafael de Oliveira, Mourão-Júnior, Carlos Alberto, Krieger, José Eduardo, Pereira, Alexandre Costa

“…This study evaluates the association of anthropometric indexes and the incidence of type 2 diabetes mellitus (T2DM) after a 5-year follow-up. This analysis…”
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Early Postnatal Cardiomyocyte Proliferation Requires High Oxidative Energy Metabolism by de Carvalho, Ana Elisa Teófilo Saturi, Bassaneze, Vinícius, Forni, Maria Fernanda, Keusseyan, Aline Alfonso, Kowaltowski, Alicia Juliana, Krieger, José Eduardo

“…Cardiac energy metabolism must cope with early postnatal changes in tissue oxygen tensions, hemodynamics, and cell proliferation to sustain development. Here,…”
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Relationship between marital status and incidence of type 2 diabetes mellitus in a Brazilian rural population: The Baependi Heart Study by de Oliveira, Camila Maciel, Viater Tureck, Luciane, Alvares, Danilo, Liu, Chunyu, Horimoto, Andrea Roseli Vançan Russo, Balcells, Mercedes, de Oliveira Alvim, Rafael, Krieger, José Eduardo, Pereira, Alexandre Costa

“…Many factors influence the incidence of type 2 diabetes mellitus (T2DM). Here, we investigated the associations between socio-demographic characteristics and…”
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Association between anthropometric indicators of adiposity and hypertension in a Brazilian population: Baependi Heart Study by de Oliveira, Camila Maciel, Ulbrich, Anderson Zampier, Neves, Felipe Silva, Dias, Fernando Augusto Lavezzo, Horimoto, Andréa Roseli Vançan Russo, Krieger, José Eduardo, Alvim, Rafael de Oliveira, Pereira, Alexandre da Costa

“…Recently, some studies have evaluated the role of adiposity measures in the prediction of hypertension risk, but the results are conflicting. Thus, the aim of…”
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Integrated systems biology approach identifies gene targets for endothelial dysfunction by Pinheiro‐de‐Sousa, Iguaracy, Fonseca‐Alaniz, Miriam Helena, Giudice, Girolamo, Valadão, Iuri Cordeiro, Modestia, Silvestre Massimo, Mattioli, Sarah Viana, Junior, Ricardo Rosa, Zalmas, Lykourgos‐Panagiotis, Fang, Yun, Petsalaki, Evangelia, Krieger, José Eduardo

“…Endothelial dysfunction (ED) is critical in the development and progression of cardiovascular (CV) disorders, yet effective therapeutic targets for ED remain…”
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Characterization of post-edited cells modified in the TFAM gene by CRISPR/Cas9 technology in the bovine model by de Oliveira, Vanessa Cristina, Gomes Mariano Junior, Clésio, Belizário, José Ernesto, Krieger, José Eduardo, Fernandes Bressan, Fabiana, Roballo, Kelly Cristine Santos, Fantinato-Neto, Paulo, Meirelles, Flávio Vieira, Chiaratti, Marcos Roberto, Concordet, Jean-Paul, Ambrósio, Carlos Eduardo

“…Gene editing in large animal models for future applications in translational medicine and food production must be deeply investigated for an increase of…”
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High-volume endurance exercise training stimulates hematopoiesis by increasing ACE NH2-terminal activity by Magalhães, Flávio de Castro, Fernandes, Tiago, Bassaneze, Vinícius, Mattos, Katt Coelho, Schettert, Isolmar, Marques, Fabio Luiz Navarro, Krieger, José Eduardo, Nava, Roberto, Barauna, Valério Garrone, Menezes de Oliveira, Edilamar

“…One of the health benefits of endurance exercise training (ET) is the stimulation of hematopoiesis. However, the mechanisms underlying ET-induced hematopoietic…”
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Renin–Angiotensin System, Hypertension, and Chronic Kidney Disease: Pharmacogenetic Implications by Lima Santos, Paulo Caleb Junior, Krieger, Jose Eduardo, Pereira, Alexandre Costa

“…About 80% of CKD (chronic kidney disease) patients are hypertensive, and kidney function and blood pressure are clearly related to both physiologic and…”
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Red wine and equivalent oral pharmacological doses of resveratrol delay vascular aging but do not extend life span in rats by da Luz, Protásio L, Tanaka, Leonardo, Brum, Patrícia Chakur, Dourado, Paulo Magno Martins, Favarato, Desidério, Krieger, José Eduardo, Laurindo, Francisco Rafael M

“…Abstract Objective To investigate, in male Wistar rats, the effects of long-term moderate red wine (RW) consumption (equivalent to ∼0.15 mg% resveratrol RS),…”
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Postprandial increase in glucagon-like peptide-1 is blunted in severe heart failure by Arruda-Junior, Daniel F, Martins, Flavia L, Salles, Thiago Almeida, Jensen, Leonardo, Dariolli, Rafael, Antonio, Ednei L, Dos Santos, Leonardo, Crajoinas, Renato O, Tucci, Paulo J F, Gowdak, Luís Henrique W, Krieger, José Eduardo, Pereira, Alexandre C, Girardi, Adriana C

“…The relationship between disturbances in glucose homeostasis and heart failure (HF) progression is bidirectional. However, the mechanisms by which HF…”
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Generation of induced pluripotent stem cells from large domestic animals by Bressan, Fabiana Fernandes, Bassanezze, Vinícius, de Figueiredo Pessôa, Laís Vicari, Sacramento, Chester Bittencourt, Malta, Tathiane Maistro, Kashima, Simone, Fantinato Neto, Paulo, Strefezzi, Ricardo De Francisco, Pieri, Naira Caroline Godoy, Krieger, José Eduardo, Covas, Dimas Tadeu, Meirelles, Flávio Vieira

“…Induced pluripotent stem cells (iPSCs) have enormous potential in developmental biology studies and in cellular therapies. Although extensively studied and…”
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Variation of mechanical properties and quantitative proteomics of VSMC along the arterial tree by Dinardo, Carla Luana, Venturini, Gabriela, Zhou, Enhua H, Watanabe, Ii Sei, Campos, Luciene Cristina Gastalho, Dariolli, Rafael, da Motta-Leal-Filho, Joaquim Maurício, Carvalho, Valdemir Melechco, Cardozo, Karina Helena Morais, Krieger, José Eduardo, Alencar, Adriano Mesquita, Pereira, Alexandre Costa

“…Vascular smooth muscle cells (VSMCs) are thought to assume a quiescent and homogeneous mechanical behavior after arterial tree development phase. However,…”
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Body adiposity index in assessing the risk of type 2 diabetes mellitus development: the Baependi Heart Study by de Oliveira, Camila Maciel, Pavani, Jessica, Krieger, José Eduardo, de Oliveira Alvim, Rafael, Mourão-Junior, Carlos Alberto, da Costa Pereira, Alexandre

“…The association between diabetes and obesity is very well established. Faced with this, several anthropometric indices of adiposity are often involved in…”
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Plasma ceramides as biomarkers for microvascular disease and clinical outcomes in diabetes and myocardial infarction by Junqueira, Debora Leonor, Cavalcanti, Alexandre Biasi, Sallum, Juliana Maria Ferraz, Yasaki, Erika, de Andrade Jesuíno, Isabella, Stach, Alline, Negrelli, Karina, de Oliveira Silva, Leila, Lopes, Marcela Almeida, Caixeta, Adriano, Chan, Mark Yy, Ching, Jianhong, Carvalho, Valdemir Malechco, Faccio, Andrea Tedesco, Tsutsui, Jeane, Rizzatti, Edgar, Fonseca, Rafael Almeida, Summers, Scott, Fonseca, Henrique Almeida, Rochitte, Carlos Eduardo, Krieger, José Eduardo, de Carvalho, Leonardo Pinto

“…Ceramides have recently been identified as novel biomarkers associated with diabetes mellitus (DM) and major adverse cardiac and cerebrovascular events…”
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Screening of MYH7 , MYBPC3 , and TNNT2 genes in Brazilian patients with hypertrophic cardiomyopathy by Marsiglia, Julia Daher Carneiro, PhD, Credidio, Flávia Laghi, BSc, de Oliveira, Théo Gremen Mimary, BSc, Reis, Rafael Ferreira, BSc, Antunes, Murillo de Oliveira, MD, de Araujo, Aloir Queiroz, MD, PhD, Pedrosa, Rodrigo Pinto, MD, PhD, Barbosa-Ferreira, João Marcos Bemfica, MD, Mady, Charles, MD, PhD, Krieger, José Eduardo, MD, PhD, Arteaga-Fernandez, Edmundo, MD, PhD, Pereira, Alexandre da Costa, MD, PhD

“…Background Hypertrophic cardiomyopathy (HC) is the most prevalent genetic cardiac disease caused by a mutation in sarcomeres, Z-disks, or calcium-handling…”
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