Search Results - "Eduardo Donadi"

Transcriptional and Posttranscriptional Regulations of the HLA-G Gene by Moreau, Philippe, Yaghi, Layale, Veiga-Castelli, Luciana C., Castelli, Erick C., Donadi, Eduardo Antônio

“…HLA-G has a relevant role in immune response regulation. The overall structure of the HLA-G coding region has been maintained during the evolution process, in…”
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Polymorphic sites at the 3' untranslated region of the HLA-G gene are associated with differential hla-g soluble levels in the Brazilian and French population by Martelli-Palomino, Gustavo, Pancotto, Joao A, Muniz, Yara C, Mendes-Junior, Celso T, Castelli, Erick C, Massaro, Juliana D, Krawice-Radanne, Irene, Poras, Isabelle, Rebmann, Vera, Carosella, Edgardo D, Rouas-Freiss, Nathalie, Moreau, Philippe, Donadi, Eduardo A

“…HLA-G molecule has well-recognized tolerogenic properties, and the encoding gene shows lower frequency of polymorphism at the coding region but higher…”
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Implications of the polymorphism of HLA-G on its function, regulation, evolution and disease association by Donadi, Eduardo A, Castelli, Erick C, Arnaiz-Villena, Antonio, Roger, Michel, Rey, Diego, Moreau, Philippe

“…The HLA-G gene displays several peculiarities that are distinct from those of classical HLA class I genes. The unique structure of the HLA-G molecule permits a…”
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Haplotypes of the HLA-G 3' Untranslated Region Respond to Endogenous Factors of HLA-G+ and HLA-G- Cell Lines Differentially by Poras, Isabelle, Yaghi, Layale, Martelli-Palomino, Gustavo, Mendes-Junior, Celso T, Muniz, Yara Costa Netto, Cagnin, Natalia F, Sgorla de Almeida, Bibiana, Castelli, Erick C, Carosella, Edgardo D, Donadi, Eduardo A, Moreau, Philippe

“…The immune checkpoint HLA-G prevents maternal rejection of the fetus and contributes in cancer invasion and acceptance of allografts. The 5' and 3' regulatory…”
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Structural Characterization of the Interaction of Hypoxia Inducible Factor-1 with Its Hypoxia Responsive Element at the -964G > A Variation Site of the HLA-G Promoter Region by Alves, Cinthia C, Donadi, Eduardo A, Giuliatti, Silvana

“…Human Antigen Leukocyte-G ( ) gene encodes an immune checkpoint molecule that has restricted tissue expression in physiological conditions; however, the gene…”
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Hypoxia inducible factor-1 mediates the expression of the immune checkpoint HLA-G in glioma cells through hypoxia response element located in exon 2 by Yaghi, Layale, Poras, Isabelle, Simoes, Renata T, Donadi, Eduardo A, Tost, Jörg, Daunay, Antoine, de Almeida, Bibiana Sgorla, Carosella, Edgardo D, Moreau, Philippe

“…HLA-G is an immune checkpoint molecule with specific relevance in cancer immunotherapy. It was first identified in cytotrophoblasts, protecting the fetus from…”
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Inflammasome genes polymorphisms may influence the development of hepatitis C in the Amazonas, Brazil by Toro, Diana Mota, Ramasawmy, Rajendranath, Silva Neto, Pedro Vieira, Pereira, Grenda Leite, Sarmento, Priscila Santos, Dray, Hanna Lara Silva Negreiros, Sousa, Keyla Santos, Affonso, Juliana Santos, Silva, Jéssica Albuquerque, Garcia, Nadja Pinto, Barbieri, Marilú Victória, Victória, Flamir Silva, Donadi, Eduardo Antônio, Costa, Allyson Guimarães, Ogusku, Mauricio Morishi, Sadahiro, Aya, Tarragô, Andréa Monteiro, Malheiro, Adriana

“…Hepatitis C is considered a major public health problem caused by the hepatitis C virus (HCV). Viral infections are known to induce production of IL1β through…”
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Variation sites at the HLA-G 3' untranslated region confer differential susceptibility to HIV/HPV co-infection and aneuploidy in cervical cell by Medeiros, Fernanda Silva, Martins, Albert Eduardo Silva, Gomes, Renan Garcia, de Oliveira, Sávio Augusto Vieira, Welkovic, Stefan, Maruza, Magda, Menezes, Maria Luiza Bezerra, Ximenes, Ricardo Arraes de Alencar, Diniz, George Tadeu Nunes, Donadi, Eduardo Antônio, Lucena-Silva, Norma

“…Post-transcriptional regulatory elements associated with transcript degradation or transcript instability have been described at the 3' untranslated region…”
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Identifying common and specific microRNAs expressed in peripheral blood mononuclear cell of type 1, type 2, and gestational diabetes mellitus patients by Collares, Cristhianna V A, Evangelista, Adriane F, Xavier, Danilo J, Rassi, Diane M, Arns, Thais, Foss-Freitas, Maria C, Foss, Milton C, Puthier, Denis, Sakamoto-Hojo, Elza T, Passos, Geraldo A, Donadi, Eduardo A

“…Regardless the regulatory function of microRNAs (miRNA), their differential expression pattern has been used to define miRNA signatures and to disclose disease…”
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Editorial: Structural modeling and computational analyses of immune system molecules by Antunes, Dinler A., Schoeder, Clara T., Baek, Minkyung, Donadi, Eduardo A.

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The + 3010/C single nucleotide polymorphism (rs1710) at the HLA-G 3′ untranslated region is associated with a short transcript exhibiting a deletion of 92 nucleotides by Castelli, Erick C., Paes, Gabriela Sato, da Silva, Isabelle Mira, Moreau, Philippe, Donadi, Eduardo A.

“…The physiological expression of HLA-G is mainly observed in the placenta, playing an essential role in maternal–fetal tolerance. Among the HLA-G mRNA…”
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High plasma soluble levels of the immune checkpoint HLA-G molecule among bodybuilders by Fernandes, Talita M, Puggina, Enrico F, Mendes-Junior, Celso T, de Paula, Milena C, Sonon, Paulin, Donadi, Eduardo A, Fernandes, Ana Paula M

“…Introduction Studies report that intense physical activity influences the down-regulation of immune function in athletes as well as the interaction between…”
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Post-transcriptional markers associated with clinical complications in Type 1 and Type 2 diabetes mellitus by Massaro, Juliana Doblas, Polli, Claudia Danella, Costa e Silva, Matheus, Alves, Cinthia Caroline, Passos, Geraldo Aleixo, Sakamoto-Hojo, Elza Tiemi, Rodrigues de Holanda Miranda, Wallace, Bispo Cezar, Nathalia Joanne, Rassi, Diane Meyre, Crispim, Felipe, Dib, Sergio Atala, Foss-Freitas, Maria Cristina, Pinheiro, Daniel Guariz, Donadi, Eduardo Antônio

“…The delayed diagnosis and the inadequate treatment of diabetes increase the risk of chronic complications. The study of regulatory molecules such as miRNAs can…”
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Congenital Zika Virus Syndrome and Autoimmunity: Two Case Reports of Type 1 Diabetes Mellitus by Arrais, Nivia Maria Rodrigues, Arrais, Ricardo Fernando, Coelho, Marília Costa, Deghaide, Neifi Hassan Saloum, Donadi, Eduardo Antônio, Maia, Claudia Rodrigues Souza, de Moraes-Pinto, Maria Isabel

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Copy number variation in the susceptibility to systemic lupus erythematosus by Barbosa, Fernanda Bueno, Simioni, Milena, Wiezel, Cláudia Emília Vieira, Torres, Fábio Rossi, Molck, Miriam Coelho, Bonilla, Melvin M, de Araujo, Tânia Kawasaki, Donadi, Eduardo Antônio, Gil-da-Silva-Lopes, Vera Lúcia, Lemos, Bernardo, Simões, Aguinaldo Luiz

“…Systemic lupus erythematosus (SLE) is an autoimmune disease with a strong genetic component and etiology characterized by chronic inflammation and autoantibody…”
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Correlation of TcII discrete typing units with severe chronic Chagas cardiomyopathy in patients from various Brazilian geographic regions by Tavares de Oliveira, Maykon, Fuzo, Carlos Alessandro, da Silva, Maria Cláudia, Donadi, Eduardo Antônio, da Silva, João Santana, Moreira, Henrique Turin, Schmidt, André, Marin-Neto, José Antônio

“…Chagas disease (ChD) is caused by Trypanosoma cruzi. The genetic structure of the species is divided into seven distinct genetic groups, TcI to TcVI, and…”
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Soluble human leukocyte antigen -G during pregnancy and infancy in Benin: Mother/child resemblance and association with the risk of malaria infection and low birth weight by d'Almeida, Tania C, Sadissou, Ibrahim, Milet, Jacqueline, Cottrell, Gilles, Mondière, Amandine, Avokpaho, Euripide, Gineau, Laure, Sabbagh, Audrey, Massougbodji, Achille, Moutairou, Kabirou, Donadi, Eduardo A, Favier, Benoit, Carosella, Edgardo, Moreau, Philippe, Rouas-Freiss, Nathalie, Courtin, David, Garcia, André

“…Human leukocyte antigen (HLA) G is a tolerogenic molecule involved in the maternal-fetal immune tolerance phenomenon. Its expression during some infectious…”
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Polimorphisms in Inflammasome Genes Are Involved in the Predisposition to Systemic Lupus Erythematosus by Pontillo, Alessandra, Girardelli, Martina, Kamada, Anselmo J., Pancotto, Joao A.t., Donadi, Eduardo A., Crovella, Sergio, Sandrin-Garcia, Paula

“…Recent findings provide evidence of inflammasome critical role in the predisposition to autoimmune disorders. The involvement of inflammasome in the…”
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Prediction of eye and hair pigmentation phenotypes using the HIrisPlex system in a Brazilian admixed population sample by Carratto, Thássia Mayra Telles, Marcorin, Letícia, do Valle-Silva, Guilherme, de Oliveira, Maria Luiza Guimarães, Donadi, Eduardo Antônio, Simões, Aguinaldo Luiz, Castelli, Erick C., Mendes-Junior, Celso Teixeira

“…Human pigmentation is a complex trait, probably involving more than 100 genes. Predicting phenotypes using SNPs present in those genes is important for…”
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Lenvatinib Plus Anti-PD-1 Combination Therapy for Advanced Cancers: Defining Mechanisms of Resistance in an Inducible Transgenic Model of Thyroid Cancer by Bertol, Bruna C, Bales, Elise S, Calhoun, Jacob D, Mayberry, Alanna, Ledezma, Melissa L, Sams, Sharon B, Orlicky, David J, Donadi, Eduardo A, Haugen, Bryan R, French, Jena D

“…Combination therapy with lenvatinib plus programmed death-1 (PD-1) immune checkpoint blockades (ICBs) is under investigation in many solid tumors, including…”
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