Search Results - "Eduard Berenshtein"
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A New Concept in Antidiabetic Therapeutics: A Concerted Removal of Labile Iron and Intracellular Deposition of Zinc
Published in Diabetes & metabolism journal (01-01-2024)“…The inflammatory process is known to be an integral part of the pathophysiology of type 2 diabetes mellitus (T2DM). The "labile," redox-active iron, serving as…”
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A New Concept in Antidiabetic Therapeutics: A Concerted Removal of Labile Iron and Intracellular Deposition of Zinc
Published in Diabetes & metabolism journal (01-03-2024)Get full text
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potential of desferrioxamine-gallium as an anti-Pseudomonas therapeutic agent
Published in Proceedings of the National Academy of Sciences - PNAS (28-10-2008)“…The opportunistic pathogen Pseudomonas aeruginosa causes infections that are difficult to treat by antibiotic therapy. This bacterium can cause biofilm…”
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Lamina Cribrosa Thickness and Spatial Relationships between Intraocular Space and Cerebrospinal Fluid Space in Highly Myopic Eyes
Published in Investigative ophthalmology & visual science (01-08-2004)“…To evaluate the spatial relationships of the intraocular space, the cerebrospinal fluid space, and the lamina cribrosa in highly myopic eyes. The study…”
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Protection by Nitric Oxide Donors of Isolated Rat Hearts Is Associated with Activation of Redox Metabolism and Ferritin Accumulation
Published in PloS one (22-07-2016)“…Preconditioning (PC) procedures (ischemic or pharmacological) are powerful procedures used for attaining protection against prolonged ischemia and reperfusion…”
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Anatomic Relationship between Lamina Cribrosa, Intraocular Space, and Cerebrospinal Fluid Space
Published in Investigative ophthalmology & visual science (01-12-2003)“…The lamina cribrosa, as the main structural element of the optic nerve head, forms a pressure barrier between the intraocular space and the retrobulbar space…”
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A New Concept in Antidiabetic Therapeutics: A Concerted Removal of Labile Iron and Intracellular Deposition of Zinc
Published in Diabetes & metabolism journal (31-01-2024)“…Background: The inflammatory process is known to be an integral part of the pathophysiology of type 2 diabetes mellitus (T2DM). The “labile,” redox-active…”
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The Loss of Myocardial Benefit following Ischemic Preconditioning Is Associated with Dysregulation of Iron Homeostasis in Diet-Induced Diabetes
Published in PloS one (26-07-2016)“…Whether the diabetic heart benefits from ischemic preconditioning (IPC), similar to the non-diabetic heart, is a subject of controversy. We recently proposed…”
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Cardiac protection by preconditioning is generated via an iron-signal created by proteasomal degradation of iron proteins
Published in PloS one (14-11-2012)“…Ischemia associated injury of the myocardium is caused by oxidative damage during reperfusion. Myocardial protection by ischemic preconditioning (IPC) was…”
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The bitter fate of the sweet heart: impairment of iron homeostasis in diabetic heart leads to failure in myocardial protection by preconditioning
Published in PloS one (15-05-2013)“…Cardiovascular dysfunction is a major complication of diabetes. Examining mechanistic aspects underlying the incapacity of the diabetic heart to respond to…”
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Degeneration modulates retinal response to transient exogenous oxidative injury
Published in PloS one (21-02-2014)“…Oxidative injury is involved in retinal and macular degeneration. We aim to assess if retinal degeneration associated with genetic defect modulates the retinal…”
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Plasma Antioxidant Status and Cell Injury after Severe Physical Exercise
Published in Proceedings of the National Academy of Sciences - PNAS (29-04-2003)“…Strenuous exercise leads to an increase in metabolic rate, increased production of reactive oxygen species, and compromised antioxidant defense systems. To…”
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HU-331, a novel cannabinoid-based anticancer topoisomerase II inhibitor
Published in Molecular cancer therapeutics (01-01-2007)“…Anthracyclines, a large group of quinonoid compounds, are used to treat some forms of cancer. Although highly effective in cancer therapy, the mechanism of…”
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Zn/Ga-DFO iron-chelating complex attenuates the inflammatory process in a mouse model of asthma
Published in Redox biology (01-01-2014)“…Redox-active iron, a catalyst in the production of hydroxyl radicals via the Fenton reaction, is one of the key participants in ROS-induced tissue injury and…”
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Aging is an organ-specific process: changes in homeostasis of iron and redox proteins in the rat
Published in AGE (01-06-2012)“…Organ-specific changes of iron- and redox-related proteins occur with age in the rat. Ferritin, the major iron storage and detoxifying protein, as well as the…”
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The Effect of Restraint Stress on the Normal Colon and on Intestinal Inflammation in a Model of Experimental Colitis
Published in Digestive diseases and sciences (01-01-2008)“…Stress may induce development of inflammation in animal models of colitis. The effects of restraint stress on oxidative damage and on antioxidants in the…”
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Flumazenil mimics whereas midazolam abolishes ischemic preconditioning in a rabbit heart model of ischemia-reperfusion
Published in Anesthesiology (Philadelphia) (01-07-2006)“…The goal of the current study was to assess the effects of flumazenil, a benzodiazepine receptor antagonist, in limiting infarct size and in reducing hydroxyl…”
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Prophylactic administration of topical glutamine enhances the capability of the rat colon to resist inflammatory damage
Published in Digestive diseases and sciences (01-10-2004)“…Glutamine is an important nutrient for the GI tract and has been shown to exert a protective effect on the bowel. Nonetheless, in the context of IBD, data…”
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Patterns of Mobilization of Copper and Iron Following Myocardial Ischemia: Possible Predictive Criteria for Tissue Injury
Published in Journal of molecular and cellular cardiology (01-11-1997)“…Direct evidence for substantial iron and copper mobilization into the coronary flow immediately following prolonged, but not short, cardiac ischemia is…”
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