Search Results - "Edson dos A. dos Santos"
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S‐(4‐Methoxyphenyl)‐4‐methoxybenzenesulfonothioate as a Promising Lead Compound for the Development of a Renal Carcinoma Agent
Published in ChemMedChem (05-03-2020)“…Organosulfur compounds show cytotoxic potential towards many tumor cell lines. Disulfides and thiosulfonates act through apoptotic processes, inducing proteins…”
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Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity
Published in Bioorganic & medicinal chemistry letters (15-08-2013)“…We have devised a procedure for the synthesis of analogs of combretastatin A-4 (CA-4) containing sulfur and selenium atoms as spacer groups between the…”
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l-Hypaphorine and d-hypaphorine: Specific antiacetylcholinesterase activity in rat brain tissue
Published in Bioorganic & medicinal chemistry letters (01-09-2021)“…[Display omitted] Acetylcholinesterase (AChEis) inhibitors are used to treat neurodegenerative diseases like Alzheimer’s disease (AD). l-Hypaphorine (l-HYP) is…”
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A potent larvicidal agent against Aedes aegypti mosquito from cardanol
Published in Anais da Academia Brasileira de Ciências (01-05-2017)“…Cardanol is a constituent of Cashew Nut Shell Liquid that presents larvicidal activity against Aedes aegypti. The isolation of cardanol is somewhat…”
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Synthesis method for thiosulfonate and report of its insecticidal activity in Anagasta kuehniella (Lepidoptera: Pyralidae)
Published in International journal of molecular sciences (19-11-2012)“…Insect pests have caused economic losses valued at billions of dollars in agricultural production. Anagasta kuehniella (Zeller), the Mediterranean flour moth,…”
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SYNTHESIS AND BIOLOGICAL ACTIVITY OF SULFUR COMPOUNDS SHOWING STRUCTURAL ANALOGY WITH COMBRETASTATIN A-4
Published in Química nova (01-01-2013)“…We extended our previous exploration of sulfur bridges as bioisosteric replacements for atoms forming the bridge between the aromatic rings of combretastatin…”
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Neuroprotective Profile of Triazole Grandisin Analogue against Amyloid-Beta Oligomer-Induced Cognitive Impairment
Published in ACS chemical neuroscience (20-12-2023)“…Alzheimer’s disease (AD) is a neurodegenerative disorder caused by accumulation of amyloid-β oligomers (AβO) in the brain, neuroinflammation, oxidative stress,…”
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Fungal bioremediation of pollutant aromatic amines
Published in Current opinion in green and sustainable chemistry (01-06-2018)“…This review addresses recent advances in fungal bioremediation of distinct pollutant aromatic amines (AAs) and their derivatives. AAs are toxic organic…”
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Synthesis, Antibacterial and Antitubercular Evaluation of Cardanol and Glycerol‑Based β-Amino Alcohol Derivatives
Published in Journal of the Brazilian Chemical Society (01-03-2018)“…The synthesis of novel amino alcohol derivatives based on cardanol and glycerol were achieved in good yields and characterized by 1H and 13C NMR (nuclear…”
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Raman spectroscopic investigation of the effects of cosmetic formulations on the constituents and properties of human skin
Published in Photomedicine and laser surgery (01-02-2012)“…This study aimed to investigate the biochemical alterations in hydration and skin proteins, which are associated with the skin aging process, caused by…”
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Effect of ramie fiber and graphene oxide on the development of PCL‐based materials: Micro‐composites, nanocomposites and hierarchical
Published in Polymer composites (12-09-2024)“…In recent years, the demand for environmentally sustainable materials has led to the exploration of biodegradable composites as alternatives to fossil‐based…”
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Polyethersulfone nanocomposite membranes with different montmorillonite clays for oil/water separation
Published in Desalination and water treatment (01-06-2019)“…Nanocomposites of polyethersulfone (PES)/clay with different types of clays were obtained to be applied in the development of flat membranes, prepared by phase…”
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Strategies for the synthesis and molecular modeling aiming to discover biorational agricultural insecticides
Published in Orbital : The Electronic Journal of Chemistry (01-06-2012)“…This work presents two proposals for the synthesis of halogenated aryl thiosulfonates which are of biologically interesting compounds. Inhibitors of…”
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Synthesis and biological activity of sulfur compounds showing structural analogy with combretastatin A-4
Published in Química Nova (01-01-2013)“…We extended our previous exploration of sulfur bridges as bioisosteric replacements for atoms forming the bridge between the aromatic rings of combretastatin…”
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