Search Results - "Edosuyi, Osaze"

Fumarate exerted an antihypertensive effect and reduced kidney injury molecule (KIM)-1 expression in deoxycorticosterone acetate-salt hypertension by Edosuyi, Osaze, Choi, Myung, Igbe, Ighodaro, Oyekan, Adebayo

“…Background: The tricarboxylic (TCA) acid cycle provides the energy needed for regulatory functions in the cardio-renal system. Recently, a genetic defect in…”
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Effects of fumarate on renal vascular reactivity and the modulation of blood pressure in normotensive rats: Possible contribution of the nitric oxide synthase-nitric oxide system by Edosuyi, Osaze, Choi, Myung, Igbe, Ighodaro, Oyekan, Adebayo

“…Introduction: Fumarate, the tricarboxylic acid (TCA) cycle intermediary, has been linked to nitric oxide (NO) produc­tion. NO plays a prominent role in the…”
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AMELIORATIVE EFFECTS OF DIMETHYL FUMARATE IN ACUTE AND CHRONIC MURINE MODELS OF DEPRESSION by Iniaghe, Loretta, Okpakpor, Eloho, Edosuyi, Osaze, Eseka, Ewere, Nedozi, Ogugua

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Harnessing the medicinal properties of Cussonia barteri Seem. (Araliaceae) in drug development. A review by Igbe, Ighodaro, Edosuyi, Osaze, Okhuarobo, Agbonlahor

“…Seem ( ) is a deciduous tree growing in savannah of Africa. Ethnomedicinally, it is used in Africa as an analgesic, anti-malarial, anti-inflammatory,…”
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Preliminary assessment of the anti-inflammatory and analgesic effects of methanol leaf extract of Cussonia barteri (Araliaceae) in rodents by Igbe, Ighodaro, Edosuyi, Osaze, Okhuarobo, Agbonlahor, Pongri, Adarki, Maduako, Nkechi, Ehimen, Isaac

“…Potato ( L.) is an important vegetable crop in Syria. Potato tuber moth is a small tree that grows in the sub-Saharan part of Africa. Various parts of the…”
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Fumarate and its downstream signalling pathways in the cardiorenal system: Recent insights and novel expositions in the etiology of hypertension by Edosuyi, Osaze, Igbe, Ighodaro, Oyekan, Adebayo

“…Hypertension, a risk factor for cardiorenal disease has a huge global health impact. Hence, there is a continuous search for new therapeutic targets and…”
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Malate reduced blood pressure and exerted differential effects on renal hemodynamics; role of the nitric oxide system and renal epithelial sodium channels (ENaC) by Edosuyi, Osaze, Adesuyi, Ayobami, Choi, Myung, Igbe, Ighodaro, Oyekan, Adebayo

“…Malate regulates blood pressure via nitric oxide production in salt-sensitive rats, a genetic model of hypertension. This study investigated the possible…”
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Effects of Fumarate on Blood Pressure and Renal Hemodynamics in Normotensive Rats: Possible Contribution of Sodium Potassium Co‐transporter (NKCC) by Edosuyi, Osaze, Choi, Myung, Igbe, Ighodaro, Oyekan, Adebayo

“…The tricarboxylic acid cycle product, fumarate, and its related products, have been implicated in the etiology of genetic and non‐genetic models of…”
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Malate Ameliorates Unilateral Ureter Obstruction (UUO)‐Induced Nephropathy Through Stimulation of Nuclear Factor Erythroid‐2 (Nrf2) and its Related Genes by Edosuyi, Osaze, Igbe, Ighodaro, Choi, Myung, Oyekan, Adebayo

“…The Tricarboxylic acid cycle (TCA) is central to the production of metabolic energy needed in the cardiorenal system. Lately, the activity of fumarase, an…”
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Fumarate Reduced Mean Arterial Blood Pressure and Improved Renal Outcomes in DOCA/salt Hypertension by Edosuyi, Osaze, Igbe, Ighodaro, Choi, Myung, Oyekan, Adebayo

“…Abstract only The mitochondria, through the tricarboxylic (TCA) acid cycle, converts organic molecules into energy that drives intricate renal blood‐pressure…”
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Malate reduced kidney injury molecule (KIM-1) expression and selectively upregulated the renal nitric oxide production in obstructive nephropathy by Edosuyi, Osaze, Choi, Myung, Edosuyi, Vashti, Igbe, Ighodaro, Oyekan, Adebayo

“…Malate, the tricarboxylic acid (TCA) cycle intermediary, upregulates renal nitric oxide (NO) signaling, and NO is renoprotective in nephropathy. This study…”
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Antinociceptive and antioxidant activities of Hunteria umbellata stem bark: possible role of the serotonergic, opioidergic and dopaminergic pathways by Edosuyi, Osaze, Igbe, Ighodaro, Iniaghe, Loretta Oghenekome

“…Background Hunteria umbellata (HU) (K. Schum) is used in ethnomedicine for the management of pain, diabetes mellitus and dysmenorrhoea. This study evaluated…”
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