Search Results - "Edmonds, M E"

Increased osteoclastic activity in acute Charcot's osteoarthopathy: the role of receptor activator of nuclear factor-kappaB ligand by Mabilleau, G, Petrova, N. L, Edmonds, M. E, Sabokbar, A

“…Aims/hypothesis Our aims were to compare osteoclastic activity between patients with acute Charcot's osteoarthropathy and diabetic and healthy controls, and to…”
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Increased Mortality in Diabetic Foot Ulcer Patients: The Significance of Ulcer Type by Chammas, N. K., Edmonds, M. E., Hill, R. L. R.

“…Diabetic foot ulcer (DFU) patients have a greater than twofold increase in mortality compared with nonulcerated diabetic patients. We investigated (a) cause of…”
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Thiazolidinediones induce osteocyte apoptosis and increase sclerostin expression by Mabilleau, G., Mieczkowska, A., Edmonds, M. E.

“…Diabet. Med. 27, 925–932 (2010) Aims  Thiazolidinediones (TZDs) are associated with a higher risk of bone fracture in women compared with men. The aim of the…”
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Audit of acute Charcot’s disease in the UK: the CDUK study by Game, F. L., Catlow, R., Jones, G. R., Edmonds, M. E., Jude, E. B., Rayman, G., Jeffcoate, W. J.

“…Aims/hypothesis We studied factors associated with the development and resolution of acute Charcot foot using a web-based observational study. Methods…”
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Acute Charcot neuro-osteoarthropathy by Petrova, NL, Edmonds, ME

“…Charcot neuro‐osteoarthropathy (CN) is one of the most challenging foot complications in diabetes. Common predisposing and precipitating factors include…”
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Five-year follow-up of a cohort of people with their first diabetic foot ulcer: the persistent effect of depression on mortality by Winkley, K., Sallis, H., Kariyawasam, D., Leelarathna, L. H., Chalder, T., Edmonds, M. E., Stahl, D., Ismail, K.

“…Aims/hypothesis Depressive disorders are associated with mortality within 18 months of presentation of diabetic foot ulcers (DFU). The main aim of this study…”
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Reliability of a novel thermal imaging system for temperature assessment of healthy feet by Petrova, N. L., Whittam, A., MacDonald, A., Ainarkar, S., Donaldson, A. N., Bevans, J., Allen, J., Plassmann, P., Kluwe, B., Ring, F., Rogers, L., Simpson, R., Machin, G., Edmonds, M. E.

“…Background Thermal imaging is a useful modality for identifying preulcerative lesions (“hot spots”) in diabetic foot patients. Despite its recognised…”
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Medical management of Charcot arthropathy by Petrova, N. L., Edmonds, M. E.

“…Charcot arthropathy is a major complication of diabetes and it poses management challenges to health care professionals. Early diagnosis and timely…”
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Inflammatory and bone turnover markers in a cross-sectional and prospective study of acute Charcot osteoarthropathy by Petrova, N. L., Dew, T. K., Musto, R. L., Sherwood, R. A., Bates, M., Moniz, C. F., Edmonds, M. E.

“…Aims To assess markers of inflammation and bone turnover at presentation and at resolution of Charcot osteoarthropathy. Methods We measured serum inflammatory…”
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Randomised controlled trial of the use of three dressing preparations in the management of chronic ulceration of the foot in diabetes by Jeffcoate, W J, Price, P E, Phillips, C J, Game, F L, Mudge, E, Davies, S, Amery, C M, Edmonds, M E, Gibby, O M, Johnson, A B, Jones, G R, Masson, E, Patmore, J E, Price, D, Rayman, G, Harding, K G

“…To determine the comparative effectiveness and cost-effectiveness of three dressing products, N-A, Inadine and Aquacel, for patients with diabetic foot ulcers,…”
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Charcot neuro-osteoarthropathy-current standards by Petrova, N. L., Edmonds, M. E.

“…It is extremely important to have a high index of suspicion for Charcot neuro‐osteoarthropathy (CN) and to encourage early presentation of the patient. This…”
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Bisphosphonates in the treatment of Charcot neuroarthropathy: a double-blind randomised controlled trial by JUDE, E. B, SELBY, P. L, BURGESS, J, LILLEYSTONE, P, MAWER, E. B, PAGE, S. R, DONOHOE, M, FOSTER, A. V. M, EDMONDS, M. E, BOULTON, A. J. M

“…The management of charcot neuroarthropathy, a severe disabling condition in diabetic patients with peripheral neuropathy, is currently inadequate with no…”
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Novel Semiquantitative Bone Marrow Oedema Score and Fracture Score for the Magnetic Resonance Imaging Assessment of the Active Charcot Foot in Diabetes by Elias, D. A., Ramnarine, R., Briody, A., Isaac, A., Donaldson, Ana, Petrova, Nina L., Meacock, L., Edmonds, Michael E.

“…There are no accepted methods to grade bone marrow oedema (BMO) and fracture on magnetic resonance imaging (MRI) scans in Charcot osteoarthropathy. The aim was…”
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Medial localization of mineralization-regulating proteins in association with Mönckeberg's sclerosis : Evidence for smooth muscle cell-mediated vascular calcification by SHANAHAN, C. M, CARY, N. R. B, SALISBURY, J. R, PROUDFOOT, D, WEISSBERG, P. L, EDMONDS, M. E

“…Calcification of the media of peripheral arteries is referred to as Mönckeberg's sclerosis (MS) and occurs commonly in aged and diabetic individuals. Its…”
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Calcaneal bone mineral density in patients with Charcot neuropathic osteoarthropathy: differences between Type 1 and Type 2 diabetes by Petrova, N. L., Foster, A. V. M., Edmonds, M. E.

“…Aims  To measure bone density and neuropathy in both feet in Type 1 and Type 2 patients with unilateral Charcot osteoarthropathy and controls. Methods …”
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Barriers to foot care in patients with diabetes as identified by healthcare professionals by Pankhurst, C. J. W., Edmonds, M. E.

“…Aims To seek the views of healthcare professionals as to the barriers to foot care that they perceive as having an impact on clinical outcomes and contributing…”
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Novel surgical treatment and gastric pathology in diabetic gastroparesis by Ejskjaer, N. T., Bradley, J. L., Buxton-Thomas, M. S., Edmonds, M. E., Howard, E. R., Purewal, T., Thomas, P. K., Watkins, P. J.

“…Summary Aims Observations are made on four Type 1 diabetic patients with the rare syndrome of intractable vomiting from confirmed gastroparesis, to determine…”
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Progress in care of the diabetic foot by Edmonds, ME

“…Major advances in the last decade have led to huge progress in care of the diabetic foot. The basic approach to management is relief of the mechanical…”
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Randomised placebo-controlled trial of granulocyte-colony stimulating factor in diabetic foot infection by Gough, A, Clapperton, M, Rolando, N, Foster, A V, Philpott-Howard, J, Edmonds, M E

“…Diabetic foot infections cause substantial morbidity and mortality. Neutrophil superoxide generation, a crucial part of neutrophil bactericidal activity, is…”
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Infrared thermography and ulcer prevention in the high‐risk diabetic foot: data from a single‐blind multicentre controlled clinical trial by Petrova, N. L., Donaldson, N. K., Tang, W., MacDonald, A., Allen, J., Lomas, C., Leech, N., Ainarkar, S., Bevans, J., Plassmann, P., Kluwe, B., Ring, F., Whittam, A., Rogers, L., McMillan, J., Simpson, R., Donaldson, A. N. A., Machin, G., Edmonds, M. E.

“…Aim To assess the usefulness of monthly thermography and standard foot care to reduce diabetic foot ulcer recurrence. Methods People with diabetes (n = 110),…”
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