Search Results - "Edmonds, Kim"

Tumor Necrosis Factor α As a New Target for Renal Cell Carcinoma: Two Sequential Phase II Trials of Infliximab at Standard and High Dose by Harrison, Michelle L, Obermueller, Eva, Maisey, Nick R, Hoare, Susan, Edmonds, Kim, Li, Ningfeng F, Chao, David, Hall, Kate, Lee, Chooi, Timotheadou, Eleni, Charles, Kellie, Ahern, Roger, King, D Mike, Eisen, Tim, Corringham, Robert, DeWitte, Mark, Balkwill, Frances, Gore, Martin

“…Tumor necrosis factor alpha (TNF-alpha) may play a role in renal cell carcinoma (RCC). We performed two sequential phase II studies of infliximab, an…”
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Strategies for assessing and managing the adverse events of sorafenib and other targeted therapies in the treatment of renal cell and hepatocellular carcinoma: Recommendations from a European nursing task group by Edmonds, Kim, Hull, Diana, Spencer-Shaw, Andrea, Koldenhof, José, Chrysou, Maria, Boers-Doets, Christine, Molassiotis, Alexander

“…Abstract Purpose As a group of European nurses familiar with treating patients with renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC) using…”
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Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2 by Au, Lewis, Fendler, Annika, Shepherd, Scott T. C., Rzeniewicz, Karolina, Cerrone, Maddalena, Byrne, Fiona, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Shon, John, Haynes, Winston A., Ward, Barry, Shum, Ben, Gordon, William, Gerard, Camille L., Xie, Wenyi, Joharatnam-Hogan, Nalinie, Young, Kate, Pickering, Lisa, Furness, Andrew J. S., Larkin, James, Harvey, Ruth, Kassiotis, George, Gandhi, Sonia, Swanton, Charles, Fribbens, Charlotte, Wilkinson, Katalin A., Wilkinson, Robert J., Lau, David K., Banerjee, Susana, Starling, Naureen, Chau, Ian, Turajlic, Samra

“…Patients with cancer are currently prioritized in coronavirus disease 2019 (COVID-19) vaccination programs globally, which includes administration of mRNA…”
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Omicron neutralising antibodies after third COVID-19 vaccine dose in patients with cancer by Fendler, Annika, Shepherd, Scott T C, Au, Lewis, Wu, Mary, Harvey, Ruth, Schmitt, Andreas M, Tippu, Zayd, Shum, Benjamin, Farag, Sheima, Rogiers, Aljosja, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Korteweg, Justine, Foley, Tara, Barber, Taja, Emslie-Henry, Andrea, Caulfield-Lynch, Niamh, Byrne, Fiona, Deng, Daqi, Kjaer, Svend, Song, Ok-Ryul, Queval, Christophe, Kavanagh, Caitlin, Wall, Emma C, Carr, Edward J, Caidan, Simon, Gavrielides, Mike, MacRae, James I, Kelly, Gavin, Peat, Kema, Kelly, Denise, Murra, Aida, Kelly, Kayleigh, O'Flaherty, Molly, Shea, Robyn L, Gardner, Gail, Murray, Darren, Yousaf, Nadia, Jhanji, Shaman, Tatham, Kate, Cunningham, David, Van As, Nicholas, Young, Kate, Furness, Andrew J S, Pickering, Lisa, Beale, Rupert, Swanton, Charles, Gandhi, Sonia, Gamblin, Steve, Bauer, David L V, Kassiotis, George, Howell, Michael, Nicholson, Emma, Walker, Susanna, Larkin, James, Turajlic, Samra

“…[...]we evaluated omicron nAbT in four patients with a history of breakthrough delta infection after two vaccine doses. The exact correlates of immune…”
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Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer by Fendler, Annika, Shepherd, Scott T.C., Au, Lewis, Wilkinson, Katalin A., Wu, Mary, Schmitt, Andreas M., Tippu, Zayd, Farag, Sheima, Rogiers, Aljosja, Harvey, Ruth, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Korteweg, Justine, Foley, Tara, Barber, Taja, Emslie-Henry, Andrea, Caulfield-Lynch, Niamh, Byrne, Fiona, Shum, Benjamin, Gerard, Camille L., Deng, Daqi, Kjaer, Svend, Song, Ok-Ryul, Queval, Christophe, Kavanagh, Caitlin, Wall, Emma C., Carr, Edward J., Namjou, Sina, Caidan, Simon, Gavrielides, Mike, MacRae, James I., Kelly, Gavin, Peat, Kema, Kelly, Denise, Murra, Aida, Kelly, Kayleigh, O’Flaherty, Molly, Shea, Robyn L., Gardner, Gail, Murray, Darren, Popat, Sanjay, Yousaf, Nadia, Jhanji, Shaman, Van As, Nicholas, Young, Kate, Furness, Andrew J.S., Pickering, Lisa, Beale, Rupert, Swanton, Charles, Gandhi, Sonia, Gamblin, Steve, Bauer, David L.V., Kassiotis, George, Howell, Michael, Nicholson, Emma, Walker, Susanna, Wilkinson, Robert J., Larkin, James, Turajlic, Samra

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An immunotherapy survivor population: health-related quality of life and toxicity in patients with metastatic melanoma treated with immune checkpoint inhibitors by O’Reilly, Aine, Hughes, Peta, Mann, Jasmine, Lai, Zhuangming, Teh, Jhia Jiat, Mclean, Emma, Edmonds, Kim, Lingard, Karla, Chauhan, Dharmisha, Lynch, Joanna, Au, Lewis, Ludlow, Aileen, Pattison, Natalie, Wiseman, Theresa, Turajlic, Samra, Gore, Martin, Larkin, James, Husson, Olga

“…Purpose The immune checkpoint inhibitors (ICIs) have resulted in subgroups of patients with metastatic melanoma achieving high-quality durable responses…”
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Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: The CAPTURE study by Fendler, Annika, Shepherd, Scott T C, Au, Lewis, Wilkinson, Katalin A, Wu, Mary, Byrne, Fiona, Cerrone, Maddalena, Schmitt, Andreas M, Joharatnam-Hogan, Nalinie, Shum, Benjamin, Tippu, Zayd, Rzeniewicz, Karolina, Boos, Laura Amanda, Harvey, Ruth, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Sarker, Sarah, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Korteweg, Justine, Foley, Tara, Bazin, Jessica, Gordon, William, Barber, Taja, Emslie-Henry, Andrea, Xie, Wenyi, Gerard, Camille L, Deng, Daqi, Wall, Emma C, Agua-Doce, Ana, Namjou, Sina, Caidan, Simon, Gavrielides, Mike, MacRae, James I, Kelly, Gavin, Peat, Kema, Kelly, Denise, Murra, Aida, Kelly, Kayleigh, O'Flaherty, Molly, Dowdie, Lauren, Ash, Natalie, Gronthoud, Firza, Shea, Robyn L, Gardner, Gail, Murray, Darren, Kinnaird, Fiona, Cui, Wanyuan, Pascual, Javier, Rodney, Simon, Mencel, Justin, Curtis, Olivia, Stephenson, Clemency, Robinson, Anna, Oza, Bhavna, Farag, Sheima, Leslie, Isla, Rogiers, Aljosja, Iyengar, Sunil, Ethell, Mark, Messiou, Christina, Cunningham, David, Chau, Ian, Starling, Naureen, Turner, Nicholas, Welsh, Liam, van As, Nicholas, Jones, Robin L, Droney, Joanne, Banerjee, Susana, Tatham, Kate C, O'Brien, Mary, Harrington, Kevin, Bhide, Shreerang, Okines, Alicia, Reid, Alison, Young, Kate, Furness, Andrew J S, Pickering, Lisa, Swanton, Charles, Gandhi, Sonia, Gamblin, Steve, Bauer, David Lv, Kassiotis, George, Kumar, Sacheen, Yousaf, Nadia, Jhanji, Shaman, Nicholson, Emma, Howell, Michael, Walker, Susanna, Wilkinson, Robert J, Larkin, James, Turajlic, Samra

“…CAPTURE (NCT03226886) is a prospective cohort study of COVID-19 immunity in patients with cancer. Here we evaluated 585 patients following administration of…”
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Abstract PO-091: CAPTURE: Cancer and COVID-19 antiviral immune monitoring study by Fendler, Annika, Boos, Laurie, Au, Lewis, Shepherd, Scott, Byrne, Fiona, Edmonds, Kim, Carlyle, Ellie, Rosario, Lyra Del, Shum, Ben, Larkin, James, Pickering, Lisa, Furness, Andrew, Turajlic, Samra

“…Abstract Introduction: Certain retrospective and registry-based studies have indicated a higher risk of COVID-19 adverse outcomes in cancer, but a detailed…”
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Erythema nodosum-like panniculitis in patients with melanoma treated with vemurafenib by Sinha, Rishika, Edmonds, Kim, Newton-Bishop, Julia, Gore, Martin, Larkin, James, Fearfield, Louise

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Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue by Litchfield, Kevin, Spain, Lavinia, Gallegos, Lisa L., Schnidrig, Desiree, Rosenbaum, Heidi, Au, Lewis, Hill, Samantha M., Thomas, Jennifer, Thompson, Lisa, Horswell, Stuart, Jones, Carol, Burgess, Daniel L., Watkins, Thomas B.K., Lim, Emilia, Birkbak, Nicolai J., Nordentoft, Iver, Pickering, Lisa, Jamal-Hanjani, Mariam, Shiu, Kai-Keen, Bridgewater, John, Hochhauser, Daniel, Forster, Martin, Papadatos-Pastos, Dionysis, Enfield, Katey, McGranahan, Nicholas, Huebner, Ariana, Parker, Peter, Walczak, Henning, Proctor, Ian, Lok, Chi-wah, Moore, David, Marafioti, Teresa, Mitchison, Miriam, Trevisan, Giorgia, Ellery, Peter, Veeriah, Selvaraju, Razaq, Maryam, Shaw, Heather, Manzano, Lizi, Summan, Simranpreet, Kanu, Nnenna, Asghar, Uzma, Tookman, Adrian, Stirling, Caroline, Edmonds, Kim, Hunter, Nikki, Mangwende, Mary, Pearce, Karla, Yan, Haixi, Fendler, Annika, Byrne, Fiona, Popat, Sanjay, Curtis, Olivia, Toncheva, Antonia, Murra, Aida, Korteweg, Justine, Josephs, Debra, Chandra, Ashish, Spicer, James, Mahadeva, Ula, Green, Anna, Stewart, Ruby, Iredale, Lara-Rose, Mackay, Tina, Deakin, Ben, Enting, Debra, Rudman, Sarah, Ghosh, Sharmistha, Karapagniotou, Lena, Pintus, Elias, Tutt, Andrew, Michalarea, Vasiliki, Brenton, James, Caldas, Carlos, Fitzgerald, Rebecca, Jimenez-Linan, Merche, Provenzano, Elena, Cluroe, Alison, Gilbertson, Richard, McDermott, Ultan, Tavare, Simon, Beddowes, Emma, Fraser, Sioban, Krebs, Matt, Dransfield, Jo, Le Quesne, John, Fennell, Dean, Langman, Gerald, Robinson, Andrew, Collard, Martin, Cockcroft, Peter, Ferris, Charlotte, Bancroft, Hollie, Kerr, Amy, Wilson, Rodelaine, Tomlinson, Ian, Loda, Massimo, McKenzie, Mairead, Larkin, James, Turajlic, Samra

“…Although thousands of solid tumors have been sequenced to date, a fundamental under-sampling bias is inherent in current methodologies. This is caused by a…”
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Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study by Fendler, Annika, Au, Lewis, Shepherd, Scott T C, Byrne, Fiona, Cerrone, Maddalena, Boos, Laura Amanda, Rzeniewicz, Karolina, Gordon, William, Shum, Benjamin, Gerard, Camille L, Ward, Barry, Xie, Wenyi, Schmitt, Andreas M, Joharatnam-Hogan, Nalinie, Cornish, Georgina H, Pule, Martin, Mekkaoui, Leila, Ng, Kevin W, Carlyle, Eleanor, Edmonds, Kim, Rosario, Lyra Del, Sarker, Sarah, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Stone, Richard, Gomes, Camila, Flynn, Helen R, Agua-Doce, Ana, Hobson, Philip, Caidan, Simon, Howell, Michael, Wu, Mary, Goldstone, Robert, Crawford, Margaret, Cubitt, Laura, Patel, Harshil, Gavrielides, Mike, Nye, Emma, Snijders, Ambrosius P, MacRae, James I, Nicod, Jerome, Gronthoud, Firza, Shea, Robyn L, Messiou, Christina, Cunningham, David, Chau, Ian, Starling, Naureen, Turner, Nicholas, Welsh, Liam, van As, Nicholas, Jones, Robin L, Droney, Joanne, Banerjee, Susana, Tatham, Kate C, Jhanji, Shaman, O'Brien, Mary, Curtis, Olivia, Harrington, Kevin, Bhide, Shreerang, Bazin, Jessica, Robinson, Anna, Stephenson, Clemency, Slattery, Tim, Khan, Yasir, Tippu, Zayd, Leslie, Isla, Gennatas, Spyridon, Okines, Alicia, Reid, Alison, Young, Kate, Furness, Andrew J S, Pickering, Lisa, Gandhi, Sonia, Gamblin, Steve, Swanton, Charles, Nicholson, Emma, Kumar, Sacheen, Yousaf, Nadia, Wilkinson, Katalin A, Swerdlow, Anthony, Harvey, Ruth, Kassiotis, George, Larkin, James, Wilkinson, Robert J, Turajlic, Samra

“…Patients with cancer have higher COVID-19 morbidity and mortality. Here we present the prospective CAPTURE study, integrating longitudinal immune profiling…”
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REFINE (REduced Frequency ImmuNE checkpoint inhibition in cancers): A multi-arm phase II basket trial testing reduced intensity immunotherapy across different cancers by Merrick, Sophie, Nankivell, Matthew, Quartagno, Matteo, Clarke, Caroline S., Joharatnam-Hogan, Nalinie, Waddell, Tom, O'Carrigan, Brent, Seckl, Michael, Ghorani, Ehsan, Banks, Emma, Edmonds, Kim, Bray, George, Woodward, Rose, Bennett, Rachel, Badrock, Jonathan, Hudson, Will, Langley, Ruth E., Vasudev, Naveen, Pickering, Lisa, Gilbert, Duncan C.

“…Immune checkpoint inhibitors (ICI) have revolutionised treating advanced cancers. ICI are administered intravenously every 2–6 weeks for up to 2 years, until…”
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Abstract 4298: Predicting tumor evolution from digital histology using AI by Spencer, Charlotte E., Camara, Axel, Riou, Auriane, Au, Lewis, Lopez, Jose I., Tippu, Zayd, Maussion, Charles, Ho, Kenneth, Strange, Amy, Nye, Emma, Birault, Veronique, Van-praet, Lydwine, Edmonds, Kim, Carlyle, Eleanor, Hazell, Steve, Rudman, Sarah, Larkin, James, Turajlic, Samra

“…Abstract Diverse clinical presentations of clear cell renal cell carcinoma (ccRCC) confound clinical decision making, leading to over and undertreatment…”
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Abstract A007: Representative sampling of invasive breast carcinomas: Interim report from a prospective study (HOLST-F) by Hanley, Brian, Gallegos, Lisa, Spain, Lavinia, Pallikonda, Husayn, Tippu, Zayd, Hill, Samantha, Barhoumi, Aoune, Byrne, Fiona, Dogva, Yulia, Gilchrist, Ashley, Noel-Storr, Glenn, Veloz, Hannah, Stanislaw, Stacey, Sansano, Harold, Edmonds, Kim, Carlyle, Eleanor, Turner, Nicholas, Larkin, James, Alexander, Nelson, Turajlic, Samra

“…Abstract Background: Although a range of therapeutic options are available in the management of invasive breast carcinomas, spatial segregation of tumour…”
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Prognostic markers and tumour growth kinetics in melanoma patients progressing on vemurafenib by Seifert, Heike, Fisher, Rosalie, Martin-Liberal, Juan, Edmonds, Kim, Hughes, Peta, Khabra, Komel, Gore, Martin, Larkin, James

“…The BRAF inhibitor vemurafenib is an effective drug in patients with BRAF mutant metastatic melanoma, but resistance occurs after a median of 6 months. The…”
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Nilotinib in KIT-driven advanced melanoma: Results from the phase II single-arm NICAM trial by Larkin, James, Marais, Richard, Porta, Nuria, Gonzalez de Castro, David, Parsons, Lisa, Messiou, Christina, Stamp, Gordon, Thompson, Lisa, Edmonds, Kim, Sarker, Sarah, Banerji, Jane, Lorigan, Paul, Evans, Thomas R. Jeffry, Corrie, Pippa, Marshall, Ernest, Middleton, Mark R., Nathan, Paul, Nicholson, Steve, Ottensmeier, Christian, Plummer, Ruth, Bliss, Judith, Valpione, Sara, Turajlic, Samra

“…Mucosal (MM) and acral melanomas (AM) are rare melanoma subtypes of unmet clinical need; 15%–20% harbor KIT mutations potentially targeted by small-molecule…”
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Abstract PR002: Advanced melanoma exhibits a diversity of evolutionary routes to lethality by Coulton, Alexander, Lobon, Irene, Spain, Lavinia, Rowan, Andrew, Shnidrig, Desiree, Shepherd, Scott, Shum, Ben, Byrne, Fiona, Au, Lewis, Edmonds, Kim, Carlyle, Ellie, Renn, Alexandra, Messiou, Christina, Spencer, Charlotte, Schmidt, Andreas M., Tippu, Zayd, Rogiers, Aljosja, Emmerich, Max, Gerard, Camille, Pallikonda, Husayn, Naceur-Lombardelli, Cristina, Foijer, Floris, van den Bos, Hilda, Wardenaar, René, Spierings, Diana, Young, Kate, Pickering, Lisa, Furness, Andrew, Borg, Elaine, Mitchison, Miriam, Moore, David, Falzon, Mary, Proctor, Ian, Stewart, Ruby, Mahadeva, Ula, Green, Anna, Larkin, James, Swanton, Charles, Jamal-Hanjani, Mariam, Litchfield, Kevin, Turajlic, Samra

“…Abstract Despite recent advances in the treatment of advanced melanoma using immune checkpoint inhibitors (ICI), 5-year overall survival remains suboptimal. A…”
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Abstract A012: Advanced melanoma exhibits a diversity of evolutionary routes to lethality by Coulton, Alexander, Lobon, Irene, Spain, Lavinia, Rowan, Andrew, Shnidrig, Desiree, Shepherd, Scott, Shum, Ben, Byrne, Fiona, Au, Lewis, Edmonds, Kim, Carlyle, Ellie, Renn, Alexandra, Messiou, Christina, Spencer, Charlotte, Schmidt, Andreas M., Tippu, Zayd, Rogiers, Aljosja, Emmerich, Max, Gerard, Camille, Pallikonda, Husayn, Naceur-Lombardelli, Cristina, Foijer, Floris, van den Bos, Hilda, Wardenaar, René, Spierings, Diana, Young, Kate, Pickering, Lisa, Furness, Andrew, Borg, Elaine, Mitchison, Miriam, Moore, David, Falzon, Mary, Proctor, Ian, Stewart, Ruby, Mahadeva, Ula, Green, Anna, Larkin, James, Swanton, Charles, Jamal-Hanjani, Mariam, Litchfield, Kevin, Turajlic, Samra

“…Abstract This abstract is being presented as a short talk in the scientific program. A full abstract is available in the Proffered Abstracts section (PR002) of…”
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Managing adverse events associated with sorafenib in renal cell carcinoma by Edmonds, Kim, Spencer-Shaw, Andrea

“…Sorafenib, a multi-targeted kinase inhibitor, is approved in Europe for the treatment of patients with advanced renal cell carcinoma whose treatment with an…”
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Managing the side effects of vemurafenib therapy: Kim Edmonds and colleagues stress the importance of identifying the symptoms of adverse events in patients being treated for metastatic melanoma and outline ways nurses can advise and support this client group by Edmonds, Kim, Burton, Julie, Gittins, Anna, Hodgetts, Jackie, McMorran, Victoria, Morgans, Cath, Sarafraz, Negin, Smith, Angela

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