Search Results - "Edlund, Christopher"

Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population by Song, Honglin, Dicks, Ed, Ramus, Susan J, Tyrer, Jonathan P, Intermaggio, Maria P, Hayward, Jane, Edlund, Christopher K, Conti, David, Harrington, Patricia, Fraser, Lindsay, Philpott, Susan, Anderson, Christopher, Rosenthal, Adam, Gentry-Maharaj, Aleksandra, Bowtell, David D, Alsop, Kathryn, Cicek, Mine S, Cunningham, Julie M, Fridley, Brooke L, Alsop, Jennifer, Jimenez-Linan, Mercedes, Høgdall, Estrid, Høgdall, Claus K, Jensen, Allan, Kjaer, Susanne Krüger, Lubiński, Jan, Huzarski, Tomasz, Jakubowska, Anna, Gronwald, Jacek, Poblete, Samantha, Lele, Shashi, Sucheston-Campbell, Lara, Moysich, Kirsten B, Odunsi, Kunle, Goode, Ellen L, Menon, Usha, Jacobs, Ian J, Gayther, Simon A, Pharoah, Paul D P

“…The aim of this study was to estimate the contribution of deleterious mutations in the RAD51B, RAD51C, and RAD51D genes to invasive epithelial ovarian cancer…”
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Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer by Ramus, Susan J, Song, Honglin, Dicks, Ed, Tyrer, Jonathan P, Rosenthal, Adam N, Intermaggio, Maria P, Fraser, Lindsay, Gentry-Maharaj, Aleksandra, Hayward, Jane, Philpott, Susan, Anderson, Christopher, Edlund, Christopher K, Conti, David, Harrington, Patricia, Barrowdale, Daniel, Bowtell, David D, Alsop, Kathryn, Mitchell, Gillian, Cicek, Mine S, Cunningham, Julie M, Fridley, Brooke L, Alsop, Jennifer, Jimenez-Linan, Mercedes, Poblete, Samantha, Lele, Shashi, Sucheston-Campbell, Lara, Moysich, Kirsten B, Sieh, Weiva, McGuire, Valerie, Lester, Jenny, Bogdanova, Natalia, Dürst, Matthias, Hillemanns, Peter, Odunsi, Kunle, Whittemore, Alice S, Karlan, Beth Y, Dörk, Thilo, Goode, Ellen L, Menon, Usha, Jacobs, Ian J, Antoniou, Antonis C, Pharoah, Paul D P, Gayther, Simon A

“…Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy, responsible for 13 000 deaths per year in the United States. Risk prediction based…”
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The sex hormone system in carriers of BRCA1/2 mutations: a case-control study by Widschwendter, Martin, Prof, Rosenthal, Adam N, PhD, Philpott, Sue, MSc, Rizzuto, Ivana, MD, Fraser, Lindsay, BSc, Hayward, Jane, MSc, Intermaggio, Maria P, MSc, Edlund, Christopher K, MSc, Ramus, Susan J, PhD, Gayther, Simon A, Prof, Dubeau, Louis, Prof, Fourkala, Evangelia Ourania, PhD, Zaikin, Alexey, Prof, Menon, Usha, Prof, Jacobs, Ian J, Prof

“…Summary Background Penetrance for breast cancer, ovarian cancer, or both in carriers of BRCA1/BRCA2 mutations is disproportionately high. Sex hormone…”
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Smokescreen: a targeted genotyping array for addiction research by Baurley, James W, Edlund, Christopher K, Pardamean, Carissa I, Conti, David V, Bergen, Andrew W

“…Addictive disorders are a class of chronic, relapsing mental disorders that are responsible for increased risk of mental and medical disorders and represent…”
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Multiple functional risk variants in a SMAD7 enhancer implicate a colorectal cancer risk haplotype by Fortini, Barbara K, Tring, Stephanie, Plummer, Sarah J, Edlund, Christopher K, Moreno, Victor, Bresalier, Robert S, Barry, Elizabeth L, Church, Timothy R, Figueiredo, Jane C, Casey, Graham

“…Genome-wide association studies (GWAS) of colorectal cancer (CRC) have led to the identification of a number of common variants associated with modest risk…”
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Genome-Wide Association of the Laboratory-Based Nicotine Metabolite Ratio in Three Ancestries by Baurley, James W., Edlund, Christopher K., Pardamean, Carissa I., Conti, David V., Krasnow, Ruth, Javitz, Harold S., Hops, Hyman, Swan, Gary E., Benowitz, Neal L., Bergen, Andrew W.

“…Metabolic enzyme variation and other patient and environmental characteristics influence smoking behaviors, treatment success, and risk of related disease…”
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Genome-wide association study of colorectal cancer in Hispanics by Schmit, Stephanie L, Schumacher, Fredrick R, Edlund, Christopher K, Conti, David V, Ihenacho, Ugonna, Wan, Peggy, Van Den Berg, David, Casey, Graham, Fortini, Barbara K, Lenz, Heinz-Josef, Tusié-Luna, Teresa, Aguilar-Salinas, Carlos A, Moreno-Macías, Hortensia, Huerta-Chagoya, Alicia, Ordóñez-Sánchez, María Luisa, Rodríguez-Guillén, Rosario, Cruz-Bautista, Ivette, Rodríguez-Torres, Maribel, Muñóz-Hernández, Linda Liliana, Arellano-Campos, Olimpia, Gómez, Donají, Alvirde, Ulices, González-Villalpando, Clicerio, González-Villalpando, María Elena, Le Marchand, Loic, Haiman, Christopher A, Figueiredo, Jane C

“…Genome-wide association studies (GWAS) have identified 58 susceptibility alleles across 37 regions associated with the risk of colorectal cancer (CRC) with P <…”
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Nicotinic acetylcholine receptor variation and response to smoking cessation therapies by Bergen, Andrew W, Javitz, Harold S, Krasnow, Ruth, Nishita, Denise, Michel, Martha, Conti, David V, Liu, Jinghua, Lee, Won, Edlund, Christopher K, Hall, Sharon, Kwok, Pui-Yan, Benowitz, Neal L, Baker, Timothy B, Tyndale, Rachel F, Lerman, Caryn, Swan, Gary E

“…OBJECTIVETo evaluate the association of nicotinic acetylcholine receptor (nAChR) single nucleotide polymorphism (SNP) with 7-day point prevalence abstinence…”
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Rare Variants in the DNA Repair Pathway and the Risk of Colorectal Cancer by Matejcic, Marco, Shaban, Hiba A, Quintana, Melanie W, Schumacher, Fredrick R, Edlund, Christopher K, Naghi, Leah, Pai, Rish K, Haile, Robert W, Levine, A Joan, Buchanan, Daniel D, Jenkins, Mark A, Figueiredo, Jane C, Rennert, Gad, Gruber, Stephen B, Li, Li, Casey, Graham, Conti, David V, Schmit, Stephanie L

“…Inherited susceptibility is an important contributor to colorectal cancer risk, and rare variants in key genes or pathways could account in part for the…”
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Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma by Igartua, Catherine, Myers, Rachel A., Mathias, Rasika A., Pino-Yanes, Maria, Eng, Celeste, Graves, Penelope E., Levin, Albert M., Del-Rio-Navarro, Blanca E., Jackson, Daniel J., Livne, Oren E., Rafaels, Nicholas, Edlund, Christopher K., Yang, James J., Huntsman, Scott, Salam, Muhammad T., Romieu, Isabelle, Mourad, Raphael, Gern, James E., Lemanske, Robert F., Wyss, Annah, Hoppin, Jane A., Barnes, Kathleen C., Burchard, Esteban G., Gauderman, W. James, Martinez, Fernando D., Raby, Benjamin A., Weiss, Scott T., Williams, L. Keoki, London, Stephanie J., Gilliland, Frank D., Nicolae, Dan L., Ober, Carole

“…Common variants at many loci have been robustly associated with asthma but explain little of the overall genetic risk. Here we investigate the role of rare…”
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A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p21.32 by Cozen, Wendy, Li, Dalin, Best, Timothy, Van Den Berg, David J., Gourraud, Pierre-Antoine, Cortessis, Victoria K., Skol, Andrew D., Mack, Thomas M., Glaser, Sally L., Weiss, Lawrence M., Nathwani, Bharat N., Bhatia, Smita, Schumacher, Fredrick R., Edlund, Christopher K., Hwang, Amie E., Slager, Susan L., Fredericksen, Zachary S., Strong, Louise C., Habermann, Thomas M., Link, Brian K., Cerhan, James R., Robison, Leslie L., Conti, David V., Onel, Kenan

“…Nodular sclerosing Hodgkin lymphoma (NSHL) is a distinct, highly heritable Hodgkin lymphoma subtype. We undertook a genome-wide meta-analysis of 393…”
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Snagger: a user-friendly program for incorporating additional information for tagSNP selection by Edlund, Christopher K, Lee, Won H, Li, Dalin, Van Den Berg, David J, Conti, David V

“…There has been considerable effort focused on developing efficient programs for tagging single-nucleotide polymorphisms (SNPs). Many of these programs do not…”
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Identification of a Novel Mucin Gene HCG22 Associated With Steroid-Induced Ocular Hypertension by Jeong, Shinwu, Patel, Nitin, Edlund, Christopher K, Hartiala, Jaana, Hazelett, Dennis J, Itakura, Tatsuo, Wu, Pei-Chang, Avery, Robert L, Davis, Janet L, Flynn, Harry W, Lalwani, Geeta, Puliafito, Carmen A, Wafapoor, Hussein, Hijikata, Minako, Keicho, Naoto, Gao, Xiaoyi, Argüeso, Pablo, Allayee, Hooman, Coetzee, Gerhard A, Pletcher, Mathew T, Conti, David V, Schwartz, Stephen G, Eaton, Alexander M, Fini, M Elizabeth

“…The pathophysiology of ocular hypertension (OH) leading to primary open-angle glaucoma shares many features with a secondary form of OH caused by treatment…”
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Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q23.1 by Biancolella, Michela, Fortini, Barbara K, Tring, Stephanie, Plummer, Sarah J, Mendoza-Fandino, Gustavo A, Hartiala, Jaana, Hitchler, Michael J, Yan, Chunli, Schumacher, Fredrick R, Conti, David V, Edlund, Christopher K, Noushmehr, Houtan, Coetzee, Simon G, Bresalier, Robert S, Ahnen, Dennis J, Barry, Elizabeth L, Berman, Benjamin P, Rice, Judd C, Coetzee, Gerhard A, Casey, Graham

“…Genome-wide association studies of colorectal cancer (CRC) have identified a number of common variants associated with modest risk, including rs3802842 at…”
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Genotype―Environment Interactions in Microsatellite Stable/ Microsatellite Instability-Low Colorectal Cancer: Results from a Genome-Wide Association Study by FIGUEIREDO, Jane C, PABLO LEWINGER, Juan, ZANKE, Brent, COTTERCHIO, Michelle, GALLINGER, Steven, JENKINS, Mark, HOPPER, John, HAILE, Robert, NEWCOMB, Polly, POTTER, John, BARON, John A, LE MARCHAND, Loic, CHI SONG, CASEY, Graham, CAMPBELL, Peter T, CONTI, David V, EDLUND, Christopher K, DUGGAN, Dave J, RANGREJ, Jagadish, LEMIRE, Mathieu, HUDSON, Thomas

“…Genome-wide association studies (GWAS) have led to the identification of a number of common susceptibility loci for colorectal cancer (CRC); however, none of…”
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A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study by Schmit, Stephanie L, Schumacher, Fredrick R, Edlund, Christopher K, Conti, David V, Raskin, Leon, Lejbkowicz, Flavio, Pinchev, Mila, Rennert, Hedy S, Jenkins, Mark A, Hopper, John L, Buchanan, Daniel D, Lindor, Noralane M, Le Marchand, Loic, Gallinger, Steven, Haile, Robert W, Newcomb, Polly A, Huang, Shu-Chen, Rennert, Gad, Casey, Graham, Gruber, Stephen B

“…Only a fraction of colorectal cancer heritability is explained by known risk-conferring genetic variation. This study was designed to identify novel risk…”
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Genetic risk factors for orofacial clefts in Central Africans and Southeast Asians by Figueiredo, Jane C., Ly, Stephanie, Raimondi, Haley, Magee, Kathy, Baurley, James W., Sanchez-Lara, Pedro A., Ihenacho, Ugonna, Yao, Caroline, Edlund, Christopher K., van den Berg, David, Casey, Graham, DeClerk, Yves A., Samet, Jonathan M., Magee III, William

“…Genome‐wide association studies (GWAS) for orofacial clefts have identified several susceptibility regions, but have largely focused on non‐Hispanic White…”
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Comprehensive analyses of DNA repair pathways, smoking and bladder cancer risk in Los Angeles and Shanghai by Corral, Roman, Lewinger, Juan Pablo, Van Den Berg, David, Joshi, Amit D., Yuan, Jian‐Min, Gago‐Dominguez, Manuela, Cortessis, Victoria K., Pike, Malcolm C., Conti, David V., Thomas, Duncan C., Edlund, Christopher K., Gao, Yu‐Tang, Xiang, Yong‐Bing, Zhang, Wei, Su, Yu‐Chen, Stern, Mariana C.

“…Tobacco smoking is a bladder cancer risk factor and a source of carcinogens that induce DNA damage to urothelial cells. Using data and samples from 988 cases…”
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15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: a GWAS in smokers by Leng, Shuguang, Liu, Yushi, Weissfeld, Joel L, Thomas, Cynthia L, Han, Younghun, Picchi, Maria A, Edlund, Christopher K, Willink, Randall P, Gaither Davis, Autumn L, Do, Kieu C, Nukui, Tomoko, Zhang, Xiequn, Burki, Elizabeth A, Van Den Berg, David, Romkes, Marjorie, Gauderman, W James, Crowell, Richard E, Tesfaigzi, Yohannes, Stidley, Christine A, Amos, Christopher I, Siegfried, Jill M, Gilliland, Frank D, Belinsky, Steven A

“…Lung cancer is the leading cause of cancer-related mortality worldwide. Detection of promoter hypermethylation of tumor suppressor genes in exfoliated cells…”
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Abstract LB-365: Novel susceptibility loci for colorectal cancer: Findings from the colorectal transdisciplinary (CORECT) study OncoArray analysis by Schmit, Stephanie L., Schumacher, Fredrick R., Edlund, Christopher K., Gong, Jian, Rennert, Gad, Zheng, Wei, Le Marchand, Loic, Peters, Ulrike, Casey, Graham, Hsu, Li, Gruber, Stephen B., Conti, David V.

“…Genome-wide association studies (GWAS) have identified 58 susceptibility alleles across 37 regions associated with the incidence of colorectal cancer (CRC)…”
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