Search Results - "Edlow, Brian L."

Joint super-resolution and synthesis of 1 mm isotropic MP-RAGE volumes from clinical MRI exams with scans of different orientation, resolution and contrast by Iglesias, Juan Eugenio, Billot, Benjamin, Balbastre, Yaël, Tabari, Azadeh, Conklin, John, Gilberto González, R., Alexander, Daniel C., Golland, Polina, Edlow, Brian L., Fischl, Bruce

“…•SynthSR turns clinical scans of different resolution and contrast into 1 mm MPRAGEs.•It relies on a CNN trained on fake images synthesized on the fly at every…”
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The Brainstem in Emotion: A Review by Venkatraman, Anand, Edlow, Brian L, Immordino-Yang, Mary Helen

“…Emotions depend upon the integrated activity of neural networks that modulate arousal, autonomic function, motor control, and somatosensation. Brainstem nodes…”
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Functional networks reemerge during recovery of consciousness after acute severe traumatic brain injury by Threlkeld, Zachary D., Bodien, Yelena G., Rosenthal, Eric S., Giacino, Joseph T., Nieto-Castanon, Alfonso, Wu, Ona, Whitfield-Gabrieli, Susan, Edlow, Brian L.

“…Integrity of the default mode network (DMN) is believed to be essential for human consciousness. However, the effects of acute severe traumatic brain injury…”
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Mapping the subcortical connectivity of the human default mode network by Li, Jian, Curley, William H., Guerin, Bastien, Dougherty, Darin D., Dalca, Adrian V., Fischl, Bruce, Horn, Andreas, Edlow, Brian L.

“…The default mode network (DMN) mediates self-awareness and introspection, core components of human consciousness. Therapies to restore consciousness in…”
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A human brain network derived from coma-causing brainstem lesions by Fischer, David B, Boes, Aaron D, Demertzi, Athena, Evrard, Henry C, Laureys, Steven, Edlow, Brian L, Liu, Hesheng, Saper, Clifford B, Pascual-Leone, Alvaro, Fox, Michael D, Geerling, Joel C

“…OBJECTIVE:To characterize a brainstem location specific to coma-causing lesions, and its functional connectivity network. METHODS:We compared 12 coma-causing…”
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The Human Connectome Project and beyond: Initial applications of 300mT/m gradients by McNab, Jennifer A., Edlow, Brian L., Witzel, Thomas, Huang, Susie Y., Bhat, Himanshu, Heberlein, Keith, Feiweier, Thorsten, Liu, Kecheng, Keil, Boris, Cohen-Adad, Julien, Tisdall, M. Dylan, Folkerth, Rebecca D., Kinney, Hannah C., Wald, Lawrence L.

“…The engineering of a 3T human MRI scanner equipped with 300mT/m gradients – the strongest gradients ever built for an in vivo human MRI scanner – was a major…”
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Restoring consciousness with pharmacologic therapy: Mechanisms, targets, and future directions by Barra, Megan E., Solt, Ken, Yu, Xin, Edlow, Brian L.

“…Severe brain injury impairs consciousness by disrupting a broad spectrum of neurotransmitter systems. Emerging evidence suggests that pharmacologic modulation…”
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Neuroanatomic Connectivity of the Human Ascending Arousal System Critical to Consciousness and Its Disorders by Edlow, Brian L, Takahashi, Emi, Wu, Ona, Benner, Thomas, Dai, Guangping, Bu, Lihong, Grant, Patricia Ellen, Greer, David M, Greenberg, Steven M, Kinney, Hannah C, Folkerth, Rebecca D

“…ABSTRACTThe ascending reticular activating system (ARAS) mediates arousal, an essential component of human consciousness. Lesions of the ARAS cause coma, the…”
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7 Tesla MRI of the ex vivo human brain at 100 micron resolution by Edlow, Brian L., Mareyam, Azma, Horn, Andreas, Polimeni, Jonathan R., Witzel, Thomas, Tisdall, M. Dylan, Augustinack, Jean C., Stockmann, Jason P., Diamond, Bram R., Stevens, Allison, Tirrell, Lee S., Folkerth, Rebecca D., Wald, Lawrence L., Fischl, Bruce, van der Kouwe, Andre

“…We present an ultra-high resolution MRI dataset of an ex vivo human brain specimen. The brain specimen was donated by a 58-year-old woman who had no history of…”
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What is a minimal clinically important difference for clinical trials in patients with disorders of consciousness? a novel probabilistic approach by Monti, Martin M, Spivak, Norman M, Edlow, Brian L, Bodien, Yelena G

“…Over the last 30 years, there has been a growing trend in clinical trials towards assessing novel interventions not only against the benchmark of statistical…”
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Measuring Consciousness in the Intensive Care Unit by Edlow, Brian L., Fecchio, Matteo, Bodien, Yelena G., Comanducci, Angela, Rosanova, Mario, Casarotto, Silvia, Young, Michael J., Li, Jian, Dougherty, Darin D., Koch, Christof, Tononi, Giulio, Massimini, Marcello, Boly, Melanie

“…Early reemergence of consciousness predicts long-term functional recovery for patients with severe brain injury. However, tools to reliably detect…”
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Editorial: Coma and disorders of consciousness: an overview by Mainali, Shraddha, Nobleza, Christa O'Hana, Edlow, Brian L, Polizzotto, Leonard, Dangayach, Neha, Sarwal, Aarti, Gosseries, Olivia

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Model-based navigation of transcranial focused ultrasound neuromodulation in humans: Application to targeting the amygdala and thalamus by Daneshzand, Mohammad, Guerin, Bastien, Kotlarz, Parker, Chou, Tina, Dougherty, Darin D., Edlow, Brian L., Nummenmaa, Aapo

“…Transcranial focused ultrasound (tFUS) neuromodulation has shown promise in animals but is challenging to translate to humans because of the thicker skull that…”
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What names for covert awareness? A systematic review by Schnakers, Caroline, Bauer, Chase, Formisano, Rita, Noé, Enrique, Llorens, Roberto, Lejeune, Nicolas, Farisco, Michele, Teixeira, Liliana, Morrissey, Ann-Marie, De Marco, Sabrina, Veeramuthu, Vigneswaran, Ilina, Kseniya, Edlow, Brian L., Gosseries, Olivia, Zandalasini, Matteo, De Bellis, Francesco, Thibaut, Aurore, Estraneo, Anna

“…Background With the emergence of Brain Computer Interfaces (BCI), clinicians have been facing a new group of patients with severe acquired brain injury who are…”
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Functional MRI Motor Imagery Tasks to Detect Command Following in Traumatic Disorders of Consciousness by Bodien, Yelena G, Giacino, Joseph T, Edlow, Brian L

“…Severe traumatic brain injury impairs arousal and awareness, the two components of consciousness. Accurate diagnosis of a patient's level of consciousness is…”
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Ethical Considerations in Clinical Trials for Disorders of Consciousness by Young, Michael J, Bodien, Yelena G, Edlow, Brian L

“…As the clinical trial landscape for patients with disorders of consciousness (DoC) expands, consideration of associated ethical challenges and opportunities is…”
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Diffusion tensor imaging in acute-to-subacute traumatic brain injury: a longitudinal analysis by Edlow, Brian L, Copen, William A, Izzy, Saef, Bakhadirov, Khamid, van der Kouwe, Andre, Glenn, Mel B, Greenberg, Steven M, Greer, David M, Wu, Ona

“…Diffusion tensor imaging (DTI) may have prognostic utility in patients with traumatic brain injury (TBI), but the optimal timing of DTI data acquisition is…”
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Automated detection of axonal damage along white matter tracts in acute severe traumatic brain injury by Maffei, Chiara, Gilmore, Natalie, Snider, Samuel B., Foulkes, Andrea S., Bodien, Yelena G., Yendiki, Anastasia, Edlow, Brian L.

“…•We proposed an automated tractography approach for individualized TAI detection.•We tested the feasibility of automated tractography in patients with acute…”
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Ascending arousal network connectivity during recovery from traumatic coma by Snider, Samuel B., Bodien, Yelena G., Frau-Pascual, Aina, Bianciardi, Marta, Foulkes, Andrea S., Edlow, Brian L.

“…•Brainstem to thalamus connectivity had the largest increase during recovery from traumatic coma.•Thalamus to temporal lobe tracts are disrupted in patients…”
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Ictal fMRI: Mapping Seizure Topography with Rhythmic BOLD Oscillations by Fischer, David, Rapalino, Otto, Fecchio, Matteo, Edlow, Brian L

“…Functional magnetic resonance imaging (fMRI) has shown elevations in the blood-oxygen-level-dependent (BOLD) signal associated with, but insensitive for,…”
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