Participation of phosphopeptides in oxidative amino acid exchange in brain tissue

Specific proteins and phosphopeptides of nervous tissue soluble in acidified organic solvents have been shown to have an active participation in the metabolism of ammonia. Nitrogen phosphopeptides (amides) bound to phosphate residues which are non stable in acids. It was shown that acid-labil nitrog...

Full description

Saved in:

Bibliographic Details
Published in:	Voprosy biokhimii mozga Vol. 13; p. 158
Main Authors:	Kometiani, P A, Edilashvili, L A, Mikeladze, D G
Format:	Journal Article
Language:	Russian
Published:	Armenia (Republic) 1978
Subjects:	Amino Acids - analysis Amino Acids - metabolism Ammonia - metabolism Animals Brain - metabolism Brain Chemistry Catalysis Cyclic AMP - metabolism Deamination Liver - analysis Membrane Proteins - metabolism Oxidation-Reduction Phosphopeptides - isolation & purification Phosphopeptides - metabolism Phosphorylation Protein Kinases - metabolism Rats
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Specific proteins and phosphopeptides of nervous tissue soluble in acidified organic solvents have been shown to have an active participation in the metabolism of ammonia. Nitrogen phosphopeptides (amides) bound to phosphate residues which are non stable in acids. It was shown that acid-labil nitrogen (amide group) of phosphopeptides, bound to phosphate risidue, participates in the metabolism of ammonia formed during the oxidative deamination of amino acids. The data obtained indicate that 3'--5'-AMP dependent proteinkinase participates in the phosphorilation of phosphopeptides.
ISSN:	0507-2972