Search Results - "Edgerton, V. Reggie"

Effect of epidural stimulation of the lumbosacral spinal cord on voluntary movement, standing, and assisted stepping after motor complete paraplegia: a case study by Harkema, Susan, Prof, Gerasimenko, Yury, PhD, Hodes, Jonathan, MD, Burdick, Joel, Prof, Angeli, Claudia, PhD, Chen, Yangsheng, PhD, Ferreira, Christie, BSc, Willhite, Andrea, BA, Rejc, Enrico, MSc, Grossman, Robert G, Prof, Edgerton, V Reggie, Prof

“…Summary Background Repeated periods of stimulation of the spinal cord and training increased the ability to control movement in animal models of spinal cord…”
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Altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans by Angeli, Claudia A., Edgerton, V. Reggie, Gerasimenko, Yury P., Harkema, Susan J.

“…A diagnosis of motor complete spinal cord injury carries a dim prognosis for recovery. However, Angeli et al. show that epidural stimulation of the spinal cord…”
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Transcutaneous Electrical Spinal Stimulation Promotes Long-Term Recovery of Upper Extremity Function in Chronic Tetraplegia by Inanici, Fatma, Samejima, Soshi, Gad, Parag, Edgerton, V. Reggie, Hofstetter, Christoph P., Moritz, Chet T.

“…Upper extremity function is the highest priority of tetraplegics for improving quality of life. We aim to determine the therapeutic potential of transcutaneous…”
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Transcutaneous electrical spinal-cord stimulation in humans by Gerasimenko, Yury, Gorodnichev, Ruslan, Moshonkina, Tatiana, Sayenko, Dimitry, Gad, Parag, Reggie Edgerton, V

“…Abstract Locomotor behavior is controlled by specific neural circuits called central pattern generators primarily located at the lumbosacral spinal cord. These…”
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Self-Assisted Standing Enabled by Non-Invasive Spinal Stimulation after Spinal Cord Injury by Sayenko, Dimitry G, Rath, Mrinal, Ferguson, Adam R, Burdick, Joel W, Havton, Leif A, Edgerton, V Reggie, Gerasimenko, Yury P

“…Neuromodulation of spinal networks can improve motor control after spinal cord injury (SCI). The objectives of this study were to (1) determine whether…”
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Neuromodulation of lumbosacral spinal networks enables independent stepping after complete paraplegia by Gill, Megan L., Grahn, Peter J., Calvert, Jonathan S., Linde, Margaux B., Lavrov, Igor A., Strommen, Jeffrey A., Beck, Lisa A., Sayenko, Dimitry G., Van Straaten, Meegan G., Drubach, Dina I., Veith, Daniel D., Thoreson, Andrew R., Lopez, Cesar, Gerasimenko, Yury P., Edgerton, V. Reggie, Lee, Kendall H., Zhao, Kristin D.

“…Spinal sensorimotor networks that are functionally disconnected from the brain because of spinal cord injury (SCI) can be facilitated via epidural electrical…”
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Weight Bearing Over-ground Stepping in an Exoskeleton with Non-invasive Spinal Cord Neuromodulation after Motor Complete Paraplegia by Gad, Parag, Gerasimenko, Yury, Zdunowski, Sharon, Turner, Amanda, Sayenko, Dimitry, Lu, Daniel C, Edgerton, V Reggie

“…We asked whether coordinated voluntary movement of the lower limbs could be regained in an individual having been completely paralyzed (>4 year) and completely…”
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Neuromodulation of evoked muscle potentials induced by epidural spinal-cord stimulation in paralyzed individuals by Sayenko, Dimitry G, Angeli, Claudia, Harkema, Susan J, Edgerton, V Reggie, Gerasimenko, Yury P

“…Epidural stimulation (ES) of the lumbosacral spinal cord has been used to facilitate standing and voluntary movement after clinically motor-complete…”
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Noninvasive Reactivation of Motor Descending Control after Paralysis by Gerasimenko, Yury P, Lu, Daniel C, Modaber, Morteza, Zdunowski, Sharon, Gad, Parag, Sayenko, Dimitry G, Morikawa, Erika, Haakana, Piia, Ferguson, Adam R, Roy, Roland R, Edgerton, V Reggie

“…The present prognosis for the recovery of voluntary control of movement in patients diagnosed as motor complete is generally poor. Herein we introduce a novel…”
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Enhancing Nervous System Recovery through Neurobiologics, Neural Interface Training, and Neurorehabilitation by Krucoff, Max O, Rahimpour, Shervin, Slutzky, Marc W, Edgerton, V Reggie, Turner, Dennis A

“…After an initial period of recovery, human neurological injury has long been thought to be static. In order to improve quality of life for those suffering from…”
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Basic Concepts of Activity-Based Interventions for Improved Recovery of Motor Function After Spinal Cord Injury by Roy, Roland R., PhD, Harkema, Susan J., PhD, Edgerton, V. Reggie, PhD

“…Abstract Roy RR, Harkema SJ, Edgerton VR. Basic concepts of activity-based interventions for improved recovery of motor function after spinal cord injury…”
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Transcutaneous Spinal Neuromodulation Reorganizes Neural Networks in Patients with Cerebral Palsy by Gad, Parag, Hastings, Susan, Zhong, Hui, Seth, Gaurav, Kandhari, Sachin, Edgerton, V. Reggie

“…Spinal neuromodulation and activity-based rehabilitation triggers neural network reorganization and enhances sensory-motor performances involving the lower…”
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A pilot study combining noninvasive spinal neuromodulation and activity-based neurorehabilitation therapy in children with cerebral palsy by Hastings, Susan, Zhong, Hui, Feinstein, Rochel, Zelczer, Gittel, Mitrovich, Christel, Gad, Parag, Edgerton, V. Reggie

“…Cerebral Palsy (CP) is the most common pediatric motor disability with multiple symptoms and etiologies. CP is exhibited through sensorimotor delays, impaired…”
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Non-invasive Neuromodulation of Spinal Cord Restores Lower Urinary Tract Function After Paralysis by Gad, Parag N, Kreydin, Evgeniy, Zhong, Hui, Latack, Kyle, Edgerton, V Reggie

“…It is commonly assumed that restoration of locomotion is the ultimate goal after spinal cord injury (SCI). However, lower urinary tract (LUT) dysfunction is…”
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Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury by Sofroniew, Michael V, Courtine, Gregoire, Song, Bingbing, Roy, Roland R, Zhong, Hui, Herrmann, Julia E, Ao, Yan, Qi, Jingwei, Edgerton, V Reggie

“…Spinal cord injuries (SCIs) in humans and experimental animals are often associated with varying degrees of spontaneous functional recovery during the first…”
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Olfactory Ensheathing Cell Transplantation after a Complete Spinal Cord Transection Mediates Neuroprotective and Immunomodulatory Mechanisms to Facilitate Regeneration by Khankan, Rana R, Griffis, Khris G, Haggerty-Skeans, James R, Zhong, Hui, Roy, Roland R, Edgerton, V Reggie, Phelps, Patricia E

“…Multiple neural and peripheral cell types rapidly respond to tissue damage after spinal cord injury to form a structurally and chemically inhibitory scar that…”
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Enabling Task-Specific Volitional Motor Functions via Spinal Cord Neuromodulation in a Human With Paraplegia by Grahn, Peter J., PhD, Lavrov, Igor A., MD, PhD, Sayenko, Dimitry G., PhD, Van Straaten, Meegan G., PT, Gill, Megan L., DPT, Strommen, Jeffrey A., MD, Calvert, Jonathan S., BS, Drubach, Dina I., DScPT, Beck, Lisa A., MS, Linde, Margaux B., BS, Thoreson, Andrew R., MS, Lopez, Cesar, MS, Mendez, Aldo A., MD, Gad, Parag N., PhD, Gerasimenko, Yury P., PhD, Edgerton, V. Reggie, PhD, Zhao, Kristin D., PhD, Lee, Kendall H., MD, PhD

“…Abstract We report a case of chronic traumatic paraplegia in which epidural electrical stimulation (EES) of the lumbosacral spinal cord enabled (1) volitional…”
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Redundancy and multifunctionality among spinal locomotor networks by Pham, Bau N, Luo, Jiangyuan, Anand, Harnadar, Kola, Olivia, Salcedo, Pia, Nguyen, Connie, Gaunt, Sarah, Zhong, Hui, Garfinkel, Alan, Tillakaratne, Niranjala, Edgerton, V Reggie

“…c-Fos is used to identify system-wide neural activation with cellular resolution in vivo. However, c-Fos can only capture neural activation of one event…”
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Rapid disuse and denervation atrophy involve transcriptional changes similar to those of muscle wasting during systemic diseases by Sacheck, Jennifer M, Hyatt, Jon-Philippe K, Raffaello, Anna, Jagoe, R. Thomas, Roy, Roland R, Edgerton, V. Reggie, Lecker, Stewart H, Goldberg, Alfred L

“…We previously identified a common set of genes, termed atrogenes, whose expression is coordinately induced or suppressed in muscle during systemic wasting…”
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Balance and Ambulation Improvements in Individuals With Chronic Incomplete Spinal Cord Injury Using Locomotor Training–Based Rehabilitation by Harkema, Susan J., PhD, Schmidt-Read, Mary, MS, DPT, Lorenz, Douglas J., PhD, Edgerton, V. Reggie, PhD, Behrman, Andrea L., PhD, PT

“…Abstract Harkema SJ, Schmidt-Read M, Lorenz DJ, Edgerton VR, Behrman AL. Balance and ambulation improvements in individuals with chronic incomplete spinal cord…”
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