Search Results - "Edge, Robert E"
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Structural characterization of the RNase E S1 domain and identification of its oligonucleotide-binding and dimerization interfaces
Published in Journal of molecular biology (30-07-2004)“…S1 domains occur in four of the major enzymes of mRNA decay in Escherichia coli: RNase E, PNPase, RNase II, and RNase G. Here, we report the structure of the…”
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Journal Article -
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A let-7 MicroRNA-sensitive Vesicular Stomatitis Virus Demonstrates Tumor-specific Replication
Published in Molecular therapy (01-08-2008)“…Creation of potent oncolytic viruses (OVs) suitable for the clinic may require new strategies in virus design. Replication-competent viruses facilitate a…”
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Journal Article -
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Exploiting differential endogenous microRNA expression to enhance oncolytic vesicular stomatitis virus tumour tropism
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Dissertation