Search Results - "Edgar, J Scott"
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Whole-genome phylogenies of the family Bacillaceae and expansion of the sigma factor gene family in the Bacillus cereus species-group
Published in BMC genomics (24-08-2011)“…The Bacillus cereus sensu lato group consists of six species (B. anthracis, B. cereus, B. mycoides, B. pseudomycoides, B. thuringiensis, and B…”
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Quantitative analysis of chondroitin sulfate disaccharides from human and rodent fixed brain tissue by electrospray ionization-tandem mass spectrometry
Published in Glycobiology (Oxford) (20-11-2019)“…Chondroitin sulfates (CS) are long, negatively charged, unbranched glycosaminoglycan (GAG) chains attached to CS-proteoglycan (CSPG) core proteins that…”
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3
Small-Molecule Inhibition of GCNT3 Disrupts Mucin Biosynthesis and Malignant Cellular Behaviors in Pancreatic Cancer
Published in Cancer research (Chicago, Ill.) (01-04-2016)“…Pancreatic cancer is an aggressive neoplasm with almost uniform lethality and a 5-year survival rate of 7%. Several overexpressed mucins that impede drug…”
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4
Compartmentalization of Chemically Separated Components into Droplets
Published in Angewandte Chemie (International ed.) (30-03-2009)“…Not merely a drop in the ocean: The integration of capillary electrophoresis (CE) with droplet generation driven by electroosmotic flow enabled the…”
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5
Using Polarization-Shaped Optical Vortex Traps for Single-Cell Nanosurgery
Published in Nano letters (01-02-2007)“…Single-cell nanosurgery and the ability to manipulate nanometer-sized subcellular structures with optical tweezers has widespread applications in biology but…”
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Surface Acoustic Wave Nebulization Facilitating Lipid Mass Spectrometric Analysis
Published in Analytical chemistry (Washington) (07-08-2012)“…Surface acoustic wave nebulization (SAWN) is a novel method to transfer nonvolatile analytes directly from the aqueous phase to the gas phase for mass…”
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Surface Acoustic Wave Nebulization Produces Ions with Lower Internal Energy than Electrospray Ionization
Published in Journal of the American Society for Mass Spectrometry (01-06-2012)“…Surface acoustic wave nebulization (SAWN) has recently been reported as a novel method to transfer non-volatile analytes directly from solution to the gas…”
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8
Human C. difficile toxin-specific memory B cell repertoires encode poorly neutralizing antibodies
Published in JCI insight (20-08-2020)“…Clostridioides difficile is a leading cause of nosocomial infection responsible for significant morbidity and mortality with limited options for therapy…”
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Use of captive spray ionization to increase throughput of the data-independent acquisition technique PAcIFIC
Published in Rapid communications in mass spectrometry (15-05-2016)“…Rationale The Precursor Acquisition Independent From Ion Count (PAcIFIC) method is a data‐independent acquisition technique capable of identifying proteins…”
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10
Phosphorylation within the cysteine-rich region of dystrophin enhances its association with β-dystroglycan and identifies a potential novel therapeutic target for skeletal muscle wasting
Published in Human molecular genetics (20-12-2014)“…Mutations in dystrophin lead to Duchenne muscular dystrophy, which is among the most common human genetic disorders. Dystrophin nucleates assembly of the…”
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Single-synapse ablation and long-term imaging in live C. elegans
Published in Journal of neuroscience methods (15-08-2008)“…Synapses are individually operated, computational units for neural communication. To manipulate physically individual synapses in a living organism, we have…”
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12
Synthesis of hyperbranched polycarbosilane modified with cyclodextrin derivatives and its application in coated capillary electrophoresis columns
Published in Journal of applied polymer science (15-11-2011)“…A series of hyperbranched polycarbosilanes were synthesized and coated on the inner surface of fused‐silica capillaries by chemical bonding. The end groups of…”
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13
Vortex-Trap-Induced Fusion of Femtoliter-Volume Aqueous Droplets
Published in Analytical chemistry (Washington) (01-01-2007)“…This paper describes the use of an optical vortex trap for the transport and fusion of single femtoliter-volume aqueous droplets. Individual droplets were…”
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14
Consensus computational network analysis for identifying candidate outer membrane proteins from Borrelia spirochetes
Published in BMC microbiology (11-07-2016)“…Similar to Gram-negative organisms, Borrelia spirochetes are dual-membrane organisms with both an inner and outer membrane. Although the outer membrane…”
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Capillary Electrophoresis Separation in the Presence of an Immiscible Boundary for Droplet Analysis
Published in Analytical chemistry (Washington) (01-10-2006)“…This paper demonstrates the ability to use capillary electrophoresis (CE) separation coupled with laser-induced fluorescence for analyzing the contents of…”
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16
Spin-to-orbital angular momentum conversion in a strongly focused optical beam
Published in Physical review letters (17-08-2007)“…As a fundamental property of light, the angular momentum of photons has been of great interest. Here, we demonstrate that optical spin-to-orbital angular…”
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Draft Genome Sequence of Pediatric Otitis Media Isolate Streptococcus pneumoniae Strain EF3030, Which Forms In Vitro Biofilms That Closely Mimic In Vivo Biofilms
Published in Microbiology resource announcements (10-01-2019)“…Here, we report the draft genome sequence of Streptococcus pneumoniae EF3030, a pediatric otitis media isolate active in biofilm assays of epithelial…”
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Selective Encapsulation of Single Cells and Subcellular Organelles into Picoliter- and Femtoliter-Volume Droplets
Published in Analytical chemistry (Washington) (15-03-2005)“…This paper describes a method, which combines optical trapping and microfluidic-based droplet generation, for selectively and controllably encapsulating a…”
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19
Monitoring Cell Survival After Extraction of a Single Subcellular Organelle Using Optical Trapping and Pulsed-Nitrogen Laser Ablation
Published in Photochemistry and photobiology (01-07-2005)“…This paper characterizes cell viability in three different cell lines—Chinese hamster ovary cells (CHO), neuroblastoma cells fused with glialoma cells…”
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Surface acoustic wave nebulization device with dual interdigitated transducers improves SAWN-MS performance
Published in Journal of mass spectrometry. (01-06-2016)“…We compared mass spectrometric (MS) performance of surface acoustic wave nebulization (SAWN) generated by a single interdigitated transducer (IDT) designed to…”
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