Search Results - "Edgar, J A"

Pyrrolizidine alkaloids in food: a spectrum of potential health consequences by Edgar, J.A, Colegate, S.M, Boppré, M, Molyneux, R.J

“…Contamination of grain with 1,2-dehydropyrrolizidine ester alkaloids (dehydroPAs) and their N-oxides is responsible for large incidents of acute and subacute…”
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Pyrrolizidine alkaloid toxicity in livestock: a paradigm for human poisoning? by Molyneux, R.J., Gardner, D.L., Colegate, S.M., Edgar, J.A.

“…Livestock poisoning, primarily liver damage, caused by consumption of plants containing 1,2-dehydropyrrolizidine ester alkaloids (dehydroPAs), and the…”
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Persistence of echimidine, a hepatotoxic pyrrolizidine alkaloid, from honey into mead by Cao, Y., Colegate, S.M., Edgar, J.A.

“…► HPLC–esiMS/MS analysis of honey and derived mead for dehydropyrrolizidine alkaloids. ► Echimidine and echiumine, characteristic of Echium plantagineum, were…”
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Pyrrolizidine alkaloids in medicinal plants from North America by Roeder, E, Wiedenfeld, H, Edgar, J A

“…Pyrrolizidine alkaloids (PAs) are mutagenic, carcinogenic, pneumotoxic, teratogenic and fetotoxic. Plants containing PAs commonly poison livestock in many…”
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Ionic Products of Bioactive Glass Dissolution Increase Proliferation of Human Osteoblasts and Induce Insulin-like Growth Factor II mRNA Expression and Protein Synthesis by Xynos, Ioannis D., Edgar, Alasdair J., Buttery, Lee D.K., Hench, Larry L., Polak, Julia M.

“…Bioglass 45S5 is an osteoproductive material, which resorbs by releasing its constitutive ions into solution. Treatment with the ionic products of Bioglass…”
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Hereditary sideroblastic anaemia due to a mutation in exon 10 of the erythroid 5‐aminolaevulinate synthase gene by EDGAR, A. J, WICKRAMASINGHE, S. N

“…DNA sequencing of the coding region of the erythroid 5‐aminolaevulinate synthase (ALAS2) cDNA from a male with pyridoxine‐responsive sideroblastic anaemia…”
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Analysis of DEXI/Dexi refines the organization of the mouse 7C and human 15q11-->q13 imprinting clusters by Kelly, M, Edgar, A J, Wevrick, R

“…Identification of imprinted genes in the Prader-Willi/Angelman syndrome deletion region is complicated by the presence of large flanking repeats. While…”
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Cloning of Dexamethasone-Induced Transcript . A Novel Glucocorticoid-Induced Gene that Is Upregulated in Emphysema by Edgar, Alasdair J, Birks, Emma J, Yacoub, Magdi H, Polak, Julia M

“…To identify changes in gene expression associated with emphysema, we used differential display to compare RNA extracted from emphysematous lungs with that of…”
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Immobilisation of IgG onto gold surfaces and its interaction with anti-IgG studied by surface plasmon resonance by Geddes, N J, Martin, A S, Caruso, F, Urquhart, R S, Furlong, D N, Sambles, J R, Than, K A, Edgar, J A

“…The optical excitation of surface plasmon resonance (SPR) at a metal dielectric interface has been used to study the binding of immunoglobulin G (IgG) to gold…”
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Serotyping of Campylobacter jejuni by slide agglutination based on heat-labile antigenic factors by Lior, H, Woodward, D L, Edgar, J A, Laroche, L J, Gill, P

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Dielectric Spectroscopic and Molecular Simulation Evidence for Aggregation of Surfactant-stabilized Calcium Carbonate Nanocolloids in Organic Media by Bearchell, C.A., Edgar, J.A., Heyes, D.M., Taylor, S.E.

“…Dielectric spectroscopy carried out on overbased phenate micelle particles of nominal diameter ∼2 nm containing calcium carbonate cores in hydrophobic liquids…”
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Neutrophils enhance expression of inducible nitric oxide synthase in human normal but not cystic fibrosis bronchial epithelial cells by Meng, Qing-Hai, Polak, Julia M., Edgar, Alasdair J., Chacon, Matilde R., Evans, Tom J., Gruenert, Dieter C., Bishop, Anne E.

“…The bronchial epithelium in cystic fibrosis (CF) expresses very low levels of the inducible form of nitric oxide synthase (iNOS). The product of iNOS, nitric…”
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Cyclin L Is an RS Domain Protein Involved in Pre-mRNA Splicing by Dickinson, Liliane A., Edgar, Alasdair J., Ehley, Jennifer, Gottesfeld, Joel M.

“…We report the cDNA cloning and functional characterization of human cyclin L, a novel cyclin related to the C-type cyclins that are involved in regulation of…”
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X-linked sideroblastic anaemia due to a mutation in the erythroid 5-aminolaevulinate synthase gene leading to an arginine170 to leucine substitution by Edgar, A. J., Vidyatilake, H. M. S., Wickramasinghe, S. N.

“…: DNA sequencing of the coding region of the erythroid 5‐aminolaevulinate synthase (ALAS2) cDNA from a male with pyridoxine‐responsive sideroblastic anaemia…”
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Lupin bean toxicity by Lowen, R J, Alam, F K, Edgar, J A

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Identification of an arginine452 to histidine substitution in the erythroid 5-aminolaevulinate synthetase gene in a large pedigree with X-linked hereditary sideroblastic anaemia by Edgar, A. J., Losowsky, M. S., Noble, J. S., Wickramasinghe, S. N.

“…:  The coding region of the erythroid 5‐aminolaevulinate synthetase gene (ALAS2) from a large pedigree with pyridoxine‐responsive X‐linked hereditary…”
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Analysis of Three Deletion Breakpoints in Xp21.1 and the Further Localization of RP3 by Brown, John, Dry, Katherine L., Edgar, Alexander J., Pryde, Fiona E., Hardwick, Lee J., Aldred, Micheala A., Lester, Douglas H., Boyle, Shelagh, Kaplan, Josseline, Dufier, Jean-Louis, Ho, Meng-Fatt, Monaco, Anthony M., Musarella, Maria A., Wright, Alan F.

“…The gene responsible for X-linked retinitis pigmentosa (xlRP) in Xp21.1 (RP3) was initially localized by deletion analysis to within a 150- to 170-kb region…”
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Pyrrolizidine alkaloid composition of three Chinese medicinal herbs, Eupatorium cannabinum, E. japonicum and Crotalaria assamica by Edgar, J A, Lin, H J, Kumana, C R, Ng, M M

“…The pyrrolizidine alkaloid composition of three Chinese herbs, "pei lan", "cheng gan cao" and "zi xiao rong," identified respectively as Eupatorium cannabinum,…”
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Loss of cell surface microvilli on rat basophilic leukaemia cells precedes secretion and can be mimicked using the calmodulin antagonist trifluoperazine by Edgar, A J, Davies, G R, Anwar, M A, Bennett, J P

“…We studied changes in cell surface morphology following treatment with secretagogue or trifluoperazine in a mast cell model. Rat basophilic leukaemia (RBL)…”
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Screening for resistance to Diaporthe toxica in lupins by estimation of phomopsins and glucoseamine in individual plants by Shankar, M, Cowling, W.A, Sweetingham, M.W, Than, K.A, Edgar, J.A, Michalewicz, A

“…Immunological and biochemical assays were developed for screening for resistance to Diaporthe toxica in individual plants of narrow‐leafed lupins (Lupinus…”
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