Search Results - "Edet, Uwem"

Health implications of the oral and dermal exposure to heavy metals in borehole water from a poorly remediated Ikot Ada Udo community, Akwa Ibom State, South-South Nigeria by Joseph, Akaninyene, Edet, Uwem, Iwok, Eno, Ekanem, Sarah

“…•The borehole water were contaminated with mean Pb, Cd, Cr, and Fe.•Children were more vulnerable to heavy metals.•The HI, HQ, and oral exposure to Cd…”
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Systematic exo-endo encapsulation of hydroxyurea (HU) by Cu, Ag, and Au-doped gallium nitride nanotubes (GaNNT) for smart therapeutic delivery by Louis, Hitler, Mbim, Elizabeth N., Okon, Gideon A., Edet, Uwem O., Benjamin, Innocent, Ejiofor, Emmanuel U., Manicum, Amanda-Lee E.

“…Similar to the more well-known carbon nanotubes, gallium nitride nanotubes (GaNNT) are among the materials that scientists have found to be extremely helpful…”
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Polypyridyl Coordinated Re(I) complexes for human tenascin-C (TNC) as an Antibreast Cancer Agent: An Intuition from Molecular Modeling and Simulations by Moherane, Lehlohonolo, Louis, Hitler, Ekereke, Ernest. E., Agwamba, Ernest C., Visser, Hendrik G., Benjamin, Innocent, Edet, Uwem O., Manicum, Amanda-Lee E.

“…Breast cancer continues to be the biggest cause of mortality for women worldwide, taking the lives of millions each year. As a result, scientists are now…”
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Evaluation of Fusobacterium nucleatum in Amniotic Fluid of Women with Preterm Labour: Fusobacterium nucleatum in Amniotic Fluid of Women with Preterm Labour by Nwaokorie, Francisca, Okunade, Kehinde S., Edet, Uwem, Obisanya, Olukayode, Ekun, Ayodele

“…Objective: The effect of Fusobacterium nucleatum, an oral commensal, on pregnancy outcomes is of global concern. This study screened for F. nucleatum and the…”
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Reactivity and Structural Investigation of Tetrahydroneoprzewaquinone A as an Anti-Inflammatory Agent: An Experimental and Molecular Modeling Perspective by Ejiofor, Emmanuel U., Ukpanukpong, Richard U., Agwamba, Ernest C., Benjamin, Innocent, Ahukwe, Eze F., Maxwell, Kube T., Edet, Uwem O., Bassey, Ini U., Muozie, Maryjane C., Manicum, Amanda-Lee Ezra, Louis, Hitler

“…This intriguing study aimed to explore the reactivity and structural investigation of (3R,3′R)-2,2′,3,3′-tetrahydroneoprzewaquinone A (THNPQ A) as a potential…”
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Circulation of hepatitis B virus genotype-E among outpatients in tertiary hospitals in the Niger-Delta region of Nigeria by F Umego, Chinenye, I Mboto, Clement, D Asitok, Atim, C Osaji, Linda, E George, Uwem, Uwem O Edet, N Mbim, Elizabeth, OC Faleye, Temitope, M Adewumi, Olubusuyi, A Adeniji, Johnson

“…Introduction: Hepatitis B virus (HBV) infection continues to be a significant public health challenge globally, with higher disease burden in developing…”
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Elucidating the antibacterial efficacy of thiadiazol derivative against carbapenem-resistant Klebsiella pneumoniae and Pseudomonas aeruginosa: An in-silico perspective by Iyam, Solomon O., Ogbodo, Sopuruchukwu E., Okafor, Ejike R., Runde, Musa, Gulack, Alpha O., Odey, Michael O., Owen, Aniekan E., Edet, Uwem, Benjamin, Innocent, Louis, Hiter

“…The sobering reality is that numerous infectious diseases can no longer be effectively treated with antibiotics, necessitating immediate attention and action…”
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Elucidating the structural basis for the enhanced antifungal activity of amide derivative against Candida albicans: a comprehensive computational investigation by Kechi, Eban L., Ubah, Chioma B., Runde, Musa, Owen, Aniekan E., Godfrey, Obinna C., Agurokpon, Daniel C., Odey, Michael O., Edet, Uwem O., Ekpong, Bassey O., Iyam, Solomon O., Benjamin, Innocent, Sampathkumar, Gopinath

“…The continuous search for more effective options against well-known pathogens such as Candida albicans remains the rationale for the search for novel lead…”
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The antimalarial profiling of Mangifera indica’s herbal formulation attenuated biochemical alterations and improved hepatocytes’ histoarchitecture in Plasmodium berghei-infected mice by Asanga, Edet E., Joseph, Akaninyene P., Okoroiwu, Henshaw U., Nelson, Promise E., Edet, Uwem O., Edet, Bassey O., Umoafia, Nikita E., Archibong, Charles, Udoh, Imaobong E., Isienyi, Chikwado C., Ikpeme, Joy G., Akpaja, Victory B., Nlemadim, Obinna M.

“…Plasmodium parasite causes malaria and affects the biochemical, physiological, and histoarchitecture of the hepatocytes and blood. The resultant effect leads…”
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Heavy metal co-resistance with antibiotics amongst bacteria isolates from an open dumpsite soil by Edet, Uwem Okon, Bassey, Ini Ubi, Joseph, Akaninyene Paul

“…Heavy metal co-resistance with antibiotics appears to be synergistic in bacterial isolates via similar mechanisms. This synergy has the potential to amplify…”
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Risk assessment and origin of metals in chicken meat and its organs from a commercial poultry farm in Akwa Ibom state, Nigeria by Edet, Uwem Okon, Joseph, Akaninyene, Bassey, Dokwo, Bassey, Itoro Nyong, Bebia, Glory P., Mbim, Elizabeth, Ogar, Agbor Yeneochia

“…Contamination of chicken with metals is on the increase, despite its known attendant health risks to human consumers. The study aimed to evaluate the…”
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Prediction of functional proteins associated with the gut microbiome of an adult population in Lagos State, Nigeria by Nwaokorie, Francisca Obiageri, Edet, Uwem Okon, Joseph, Akaninyene Paul, Phylis, Kanki, Folasade, Ogunsola

“…The human gut microbiome is implicated in health and disease. Yet, its functions in healthy adults from a divergent population like those seen in Africa are…”
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Evaluation of Annona muricata extract against Staphylococcus aureus isolate and in-silico activity of bioactive compounds against Capsular protein (Cap5O) by Edet, Uwem Okon, Nwaokorie, Francisca Obiageri, Mbim, Elizabeth Nkagafel, Asanga, Edet Effiong, Agbor, Yeneochia Ogar, Okoroiwu, Henshaw Uchechi, Edet, Bassey Okon, Umoafia, Nikita, Nkang, Ani

“…Background Staphylococcus aureus has prevailed against the majority of antibiotics currently in clinical use, making it a significant global public health…”
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Geometry optimization, impact of solvation on the spectral (FT-IR, UV, NMR) analysis, Quantum chemical parameters, and the bioactivity of feruloyltyramine as a potential anti-Lassa virus agent via molecular docking by Eyo, Antai E., Obadiah, Gulack A., Benjamin, Innocent, Edet, Uwem O., Akor, Faith O., Mbim, Elizabeth, Nkang, Ani, Richard, Ibor, Emmanuel, Emmanuel, Ayoola, Oluwadamilola V., Joshua, Godwin, Louis, Hitler

“…The unrelenting menace of the Lassa virus, characterized by its high mortality rate and the potential for global dissemination, underscores an urgent call for…”
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In- silico evaluation of bioactive compounds from selected medicinal plants from Southern Nigeria against hepatitis C virus genotype 1 RNA-directed RNA polymerase by Mboto, Clement I., Edet, Uwem O., Mbim, Elizabeth N., Ndifon, Wilfred O., Ebenso, Eno E., Egharevba, Henry O., George, Uwem E., Nwaokorie, Francisca O., Udo, Samuel.I.

“…At the moment, there is no vaccine for the hepatitis C virus (HCV), despite it being more infectious than the hepatitis B virus (HBV) and the human…”
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Impacts of sunlight exposure on physicochemical parameters, potential toxic metals, and microbial characteristics of sachet drinking water sold in Calabar metropolis, Nigeria by Umoafia, Nikita Elkanah, Edet, Uwem Okon, Joseph, Akaninyene Paul, Henshaw, Okoroiwu Uchechi, Mbim, Elizabeth Nkagafel, Obeten, Honour, Edet, Bassey Okon, Edet, Asanga, Ibor, Oju Richard, Nkang, Nkoyo, Louis, Hitler, Nwaokorie, Francisca O., Nkang, Ani

“…Poor handling of potable water is a well-known route of contamination. Despite this, Nigeria’s most consumed packaged potable water called “sachet” or “pure…”
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Correction to: Impacts of sunlight exposure on physicochemical parameters, potential toxic metals, and microbial characteristics of sachet drinking water sold in Calabar metropolis, Nigeria by Umoafia, Nikita Elkanah, Edet, Uwem Okon, Joseph, Akaninyene Paul, Henshaw, Okoroiwu Uchechi, Mbim, Elizabeth Nkagafel, Obeten, Honour, Edet, Bassey Okon, Edet, Asanga, Ibor, Oju Richard, Nkang, Nkoyo, Louis, Hitler, Nwaokorie, Francisca O., Nkang, Ani

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Microbial structure and function diversity of open dumpsite compost used as fertilizer by peasant farmers by Bassey, Ini Ubi, Edet, Uwem Okon, Umoafia, Nikita Grace, Nwachi, Anthonia Chinyere, Ebenge, Iniobong Andy, Odokuma, Lucky

“…•Compost samples were in mesophilic and maturation stages.•Uncultured taxonomic groups and potential pathogens detected.•Carbohydrate metabolism was dominant…”
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Occurrence, identification and characterization of plastic pollution from an open solid waste dumpsite in Calabar, Southern Nigeria by Ibor, Oju R., Mpama, Nten-Osowo L., Okoli, Chukwunonso P., Ogarekpe, Dinah M., Edet, Uwem O., Ajang, Raymond O., Onyezobi, Chinedu E., Anyanti, Jennifer, Idogho, Omokhudu, Aizobu, Dennis, Arukwe, Augustine

“…•21 plastic pollutants were sampled from the dumpsite and categorized into ten representative plastic types.•PET bottles, LDPE, PP, HDPE, PS tray, PVC fiber…”
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Antimicrobial analysis of honey against Staphylococcus aureus isolates from wound, ADMET properties of its bioactive compounds and in-silico evaluation against dihydropteroate synthase by Edet, Uwem Okon, Mbim, Elizabeth Nkagafel, Ezeani, Esu, Henshaw, Okoroiwu Uchechi, Ibor, Oju R, Bassey, Ini Ubi, Asanga, Edet Effiong, Antai, Ekpo Eyo, Nwaokorie, Francisca O, Edet, Bassey Okon, Bebia, Glory P, Tega, Curtis, Mboto, Clement I, Nkang, Ani, Nneoyi-Egbe, Ada Francesca

“…One of the main challenges of wound healing is infection with multi-drug resistant (MDR) bacteria such as Staphylococcus aureus. The spectrum of antibiotics…”
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