Search Results - "Eder, Sebastian K."

Changing Metabolic Patterns along the Colorectal Adenoma-Carcinoma Sequence by Tevini, Julia, Eder, Sebastian K, Huber-Schönauer, Ursula, Niederseer, David, Strebinger, Georg, Gostner, Johanna M, Aigner, Elmar, Datz, Christian, Felder, Thomas K

“…Colorectal cancer (CRC) is a major public health burden and one of the leading causes of cancer-related deaths worldwide. Screening programs facilitate early…”
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A single‐center cohort study of patients with hereditary spherocytosis in Central Europe reveals a high frequency of novel disease‐causing genotypes by Kager, Leo, Jimenez‐Heredia, Raúl, Zeitlhofer, Petra, Novak, Wolfgang, Eder, Sebastian K., Segarra‐Roca, Anna, Frohne, Alexandra, Nebral, Karin, Haimel, Matthias, Geyeregger, René, Roetzer‐Londgin, Katharina, Haas, Oskar A., Boztug, Kaan

“…Next-generation sequencing (NGS) has helped elucidate pathogenic variants underlying HS, the complexity of inheritance modes, and genotype–phenotype…”
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Metabolomic profiling identifies potential pathways involved in the interaction of iron homeostasis with glucose metabolism by Stechemesser, Lars, Eder, Sebastian K, Wagner, Andrej, Patsch, Wolfgang, Feldman, Alexandra, Strasser, Michael, Auer, Simon, Niederseer, David, Huber-Schönauer, Ursula, Paulweber, Bernhard, Zandanell, Stephan, Ruhaltinger, Sandra, Weghuber, Daniel, Haschke-Becher, Elisabeth, Grabmer, Christoph, Rohde, Eva, Datz, Christian, Felder, Thomas K, Aigner, Elmar

“…Abstract Objective Elevated serum ferritin has been linked to type 2 diabetes (T2D) and adverse health outcomes in subjects with the Metabolic Syndrome (MetS)…”
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Clinical and Metabolic Characterization of Lean Caucasian Subjects With Non-alcoholic Fatty Liver by Feldman, Alexandra, Eder, Sebastian K, Felder, Thomas K, Kedenko, Lyudmyla, Paulweber, Bernhard, Stadlmayr, Andreas, Huber-Schönauer, Ursula, Niederseer, David, Stickel, Felix, Auer, Simon, Haschke-Becher, Elisabeth, Patsch, Wolfgang, Datz, Christian, Aigner, Elmar

“…Non-alcoholic fatty liver disease (NAFLD) is closely linked to obesity; however, 5-8% of lean subjects also have evidence of NAFLD. We aimed to investigate…”
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Clinical evaluation of fully automated thigh muscle and adipose tissue segmentation using a U-Net deep learning architecture in context of osteoarthritic knee pain by Kemnitz, Jana, Baumgartner, Christian F., Eckstein, Felix, Chaudhari, Akshay, Ruhdorfer, Anja, Wirth, Wolfgang, Eder, Sebastian K., Konukoglu, Ender

“…Objective Segmentation of thigh muscle and adipose tissue is important for the understanding of musculoskeletal diseases such as osteoarthritis. Therefore, the…”
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Local MRI-based measures of thigh adipose tissue derived from fully automated deep convolutional neural network-based segmentation show a comparable responsiveness to bidirectional change in body weight as from quality controlled manual segmentation by Kemnitz, Jana, Steidle-Kloc, Eva, Wirth, Wolfgang, Fuerst, David, Wisser, Anna, Eder, Sebastian K., Eckstein, Felix

“…•Clinical study can be reproduced by fully automated deep learning segmentation.•Segmentation time is< 1 s for thigh MR adipose tissue.•Similar sensitivity to…”
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Evans syndrome caused by a deleterious mutation affecting the adaptor protein SASH3 by Novak, Wolfgang, Berner, Jakob, Svaton, Michael, Jimenez‐Heredia, Raul, Segarra‐Roca, Anna, Frohne, Alexandra, Guiliani, Sarah, Rouhani, David, Eder, Sebastian K., Rottal, Arno, Trapin, Doris, Scheuchenstuhl, Anja, Pickl, Winfried F., Simonitsch‐Klupp, Ingrid, Kager, Leo, Boztug, Kaan

“…Summary Increasing evidence suggests multilineage cytopenias (also known as Evans syndrome) may be caused by inborn errors of immunity (IEI) with immune…”
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Mesenchymal iron deposition is associated with adverse long‐term outcome in non‐alcoholic fatty liver disease by Eder, Sebastian K., Feldman, Alexandra, Strebinger, Georg, Kemnitz, Jana, Zandanell, Stephan, Niederseer, David, Strasser, Michael, Haufe, Heike, Sotlar, Karl, Stickel, Felix, Paulweber, Bernhard, Datz, Christian, Aigner, Elmar

“…Background & Aims Approximately one‐third of patients with non‐alcoholic fatty liver disease (NAFLD) show signs of mild‐to‐moderate iron overload. The impact…”
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Vemurafenib acts as a molecular on-off switch governing systemic inflammation in Langerhans cell histiocytosis by Eder, Sebastian K., Schwentner, Raphaela, Ben Soussia, Philipp, Abagnale, Giulio, Attarbaschi, Andishe, Minkov, Milen, Halbritter, Florian, Hutter, Caroline

“…Langerhans cell histiocytosis (LCH) is a neoplasm marked by the accumulation of CD1A+CD207+ cells. It is most commonly driven by a somatic, activating mutation…”
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Lean Patients with Non-Alcoholic Fatty Liver Disease Have a Severe Histological Phenotype Similar to Obese Patients by Denkmayr, Lukas, Feldman, Alexandra, Stechemesser, Lars, Eder, Sebastian K, Zandanell, Stephan, Schranz, Michael, Strasser, Michael, Huber-Schönauer, Ursula, Buch, Stephan, Hampe, Jochen, Paulweber, Bernhard, Lackner, Carolin, Haufe, Heike, Sotlar, Karl, Datz, Christian, Aigner, Elmar

“…A small proportion of lean patients develop non-alcoholic fatty liver disease (NAFLD). We aimed to report the histological picture of lean NAFLD in comparison…”
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Trans-Iliac Bypass Grafting for Vascular Groin Complications by Enzmann, Florian K., Nierlich, Patrick, Eder, Sebastian K., Aspalter, Manuela, Dabernig, Werner, Aschacher, Thomas, Linni, Klaus, Hölzenbein, Thomas J.

“…Groin complications following vascular reconstruction, extensive trauma, or severe radiation induced scarring may complicate future revascularisation…”
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Tibiodistal vein bypass in critical limb ischemia and its role after unsuccessful tibial angioplasty by Enzmann, Florian K., Eder, Sebastian K., Aschacher, Thomas, Aspalter, Manuela, Nierlich, Patrick, Linni, Klaus, Hölzenbein, Thomas J.

“…Technical progress in angioplasty expanded its application to very distal arterial lesions of the lower extremity. In cases of unsuccessful angioplasty…”
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Su2019 Dimethylarginine Serum Concentrations Effectively Identify Subjects With Colorectal Carcinoma by Eder, Sebastian K, Felder, Thomas K, Stadlmayr, Andreas, Huber-Schönauer, Ursula, Niederseer, David, Patsch, Wolfgang, Aigner, Elmar, Datz, Christian

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Long-Term Follow-Up of Tibio-Distal Vein Bypass for Failed Tibial Angioplasty by Enzmann, Florian K, Eder, Sebastian K, Nierlich, Patrick, Aspalter, Manuela, Guggenbichler, Siegmund, Dabernig, Werner, Hölzenbein, Thomas J

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METB-03. THE DISTINCT GENOMICS OF HIGH-GRADE INFANT GLIOMAS AMONG PEDIATRIC GLIOMAS HARBORING RECEPTOR TYROSINE KINASE FUSIONS by de Biagi-Junior, Carlos A O, Eder, Sebastian K, LaBelle, Jenna, Filbin, Mariella G

“…Abstract Gliomas account for about 60% of pediatric brain tumors, about half of which are classified as high-grade. Recent studies have shown that infants with…”
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Liver-related Mortality is Increased in Lean Subjects with Non- alcoholic Fatty Liver Disease Compared to Overweight and Obese Subjects by Feldman, Alexandra, Wernly, Bernhard, Strebinger, Georg, Eder, Sebastian Karl, Zandanell, Stephan, Niederseer, David, Strasser, Michael, Haufe, Heike, Sotlar, Karl, Paulweber, Bernhard, Datz, Christian, Aigner, Elmar

“…Although non-alcoholic fatty liver disease (NAFLD) is linked to obesity, a proportion of lean subjects also have NAFLD with potentially distinct clinical…”
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Parathyroid Hormone is Related to Dysplasia and a Higher Rate of Distal Colorectal Adenoma in Women but Not Men by Aigner, Elmar, Stadlmayr, Andreas, Huber-Schönauer, Ursula, Zwerina, Jochen, Husar-Memmer, Emma, Niederseer, David, Eder, Sebastian K., Stickel, Felix, Pirich, Christian, Schett, Georg, Patsch, Wolfgang, Datz, Christian

“…Molecular and clinical observations provide evidence for a potential role of parathyroid hormone (PTH) in colorectal cancer development. We therefore aimed to…”
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Abstract 2857: Perspectives from a systematic review of kinase fusion oncogenes and access to corresponding kinase inhibitor clinical trials in pediatric, adolescent, and young adult solid malignancies by Vega, Lorena Lazo de la, Eder, Sebastian K., Sukharevsky, Ellen, Kahn, Zachary A., O'Connell, Michaela, Wachter, Franziska, Anderson, Emily P., Trissal, Maria C., LaBelle, Jenna J., Carpenter, Kendall, Kager, Leo, Filbin, Mariella G., Janeway, Katherine A.

“…Abstract Oncogenic kinase fusions (KFs) have been reported in pediatric, adolescent, and young adult (P-AYA) brain tumors, sarcomas, and rare solid…”
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Combining Heterogeneously Labeled Datasets For Training Segmentation Networks by Kemnitz, Jana, Baumgartner, Christian F, Wirth, Wolfgang, Eckstein, Felix, Eder, Sebastian K, Konukoglu, Ender

“…Accurate segmentation of medical images is an important step towards analyzing and tracking disease related morphological alterations in the anatomy…”
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