Search Results - "Eden, O.B"

The development of evidence-based guidelines on mouth care for children, teenagers and young adults treated for cancer by Glenny, A.M, Gibson, F, Auld, E, Coulson, S, Clarkson, J.E, Craig, J.V, Eden, O.B, Khalid, T, Worthington, H.V, Pizer, B

“…Abstract The aim was to produce evidence-based guidelines on mouth care for children, teenagers and young adults receiving chemotherapy and/or radiotherapy…”
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Age-incidence patterns of primary CNS tumors in children, adolescents, and adults in England by Arora, Ramandeep S, Alston, Robert D, Eden, Tim O B, Estlin, Edward J, Moran, Anthony, Birch, Jillian M

“…Around 25% of all tumors in those 0-14 years of age and 9% in those 15-24 years of age involve the CNS. They are the most common cause of cancer-related deaths…”
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49 INVITED Why are Adolescents Diagnosed Later With Cancer? by Gibson, F, Pearce, S, Eden, O.B, Glaser, A, Hooker, L, Whelan, J, Kelly, D

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A dyad of lymphoblastic lysosomal cysteine proteases degrades the antileukemic drug L-asparaginase by Patel, Naina, Krishnan, Shekhar, Offman, Marc N, Krol, Marcin, Moss, Catherine X, Leighton, Carly, van Delft, Frederik W, Holland, Mark, Liu, Jizhong, Alexander, Seema, Dempsey, Clare, Ariffin, Hany, Essink, Monika, Eden, Tim O B, Watts, Colin, Bates, Paul A, Saha, Vaskar

“…l-Asparaginase is a key therapeutic agent for treatment of childhood acute lymphoblastic leukemia (ALL). There is wide individual variation in…”
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Are reported increases in incidence of primary CNS tumours real? An analysis of longitudinal trends in England, 1979–2003 by Arora, Ramandeep S, Alston, Robert D, Eden, Tim O.B, Estlin, Edward J, Moran, Anthony, Geraci, Marco, Birch, Jillian M

“…Abstract Reported increases in the incidence of CNS tumours in the developed world in the 1970s to 1990s have been a cause for concern and debate. It still…”
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1219 POSTER Cancer mortality in 13 to 29 year olds in England and Wales, 1981–2005 by Geraci, M, Birch, J.M, Eden, O.B, Moran, A, Alston, R.D

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Balancing high accrual and ethical recruitment in paediatric oncology: a qualitative study of the 'look and feel' of clinical trial discussions by Byrne-Davis, Lucie M T, Salmon, Peter, Gravenhorst, Katja, Eden, Tim O B, Young, Bridget

“…High accrual to clinical trials enables new treatment strategies to be tested rapidly, accurately and with generalisability. Ethical standards also must be…”
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The international scandal of defective asparaginase: A blight on children with cancer by Barr, Ronald D., Furneaux, Rosa, Margottini, Laura, Eden, Tim O. B.

“…Acute lymphoblastic leukemia is the commonest form of cancer in children and adolescents worldwide, and asparaginase is an essential component of successful…”
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Platinum agents in the treatment of osteosarcoma: Efficacy of cisplatin vs. carboplatin in human osteosarcoma cell lines by Robson, H., Meyer, S., Shalet, S.M., Anderson, E., Roberts, S., Eden, O.B.

“…Background Cisplatin (cDDP), when used either alone or, more often, in combination with other agents, especially adriamycin, achieves a high response rate in…”
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Comparative incidence patterns and trends of gonadal and extragonadal germ cell tumors in England, 1979 to 2003 by Arora, Ramandeep S., Alston, Robert D., Eden, Tim O. B., Geraci, Marco, Birch, Jillian M

“…BACKGROUND: It is believed that gonadal and extragonadal germ cell tumors (GCTs) arise from primordial germ cells and may have similar etiopathogenesis. Unlike…”
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Treatment non-adherence in teenage and young adult patients with cancer by Kondryn, Helena J, PhD, Edmondson, Claire L, MBChB, Hill, Jonathan, Prof, Eden, Tim OB, Prof

“…Summary Adhering to treatment can be a significant issue for many patients diagnosed with chronic health conditions and this has been reported to be greater…”
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The contrasting age-incidence patterns of bone tumours in teenagers and young adults: Implications for aetiology by Arora, Ramandeep S., Alston, Robert D., Eden, Tim O.B., Geraci, Marco, Birch, Jillian M.

“…Bone tumours comprise 0.2% of cancers overall but 5.7% in 15–24 year olds. To explore the relationship with adolescence we have analysed age‐incidence patterns…”
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Benefit of dexamethasone compared with prednisolone for childhood acute lymphoblastic leukaemia: results of the UK Medical Research Council ALL97 randomized trial by Mitchell, C. D., Richards, S. M., Kinsey, S. E., Lilleyman, J., Vora, A., Eden, T. O. B.

“…Summary Corticosteroids are an essential component of treatment for acute lymphoblastic leukaemia (ALL). Prednisolone is the most commonly used steroid,…”
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Parental coping and the course of depression over nine months following the diagnosis of childhood cancer by Hill, J., Eden, O.B., Mackie, E.

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An infectious aetiology for childhood acute leukaemia: a review of the evidence by McNally, Richard J. Q., Eden, Tim O. B.

“…Summary There are three current hypotheses concerning infectious mechanisms in the aetiology of childhood leukaemia: exposure in utero or around the time of…”
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Variables Affecting Kinetics of Minimal Residual Disease Clearance in Children with Lymphoblastic Leukaemia; Results of the United Kingdom Medical Research Council (UK MRC) Protocols ALL97, ALL97/99 and ALL2003 by Vora, Ajay J., Richards, S., Hancock, J., Mitchell, C., Eden, O.B., Kinsey, S., Hann, I., Lilleyman, J.S., Goulden, N.

“…We studied the influence of patient, leukaemia and treatment characteristics on the kinetics of Minimal Residual Disease (MRD) clearance in children with…”
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Association of acute parvovirus B19 infection with new onset of acute lymphoblastic and myeloblastic leukaemia by Kerr, J R, Barah, F, Cunniffe, V S, Smith, J, Vallely, P J, Will, A M, Wynn, R F, Stevens, R F, Taylor, G M, Cleator, G M, Eden, O B

“…Aims: To investigate the association of acute parvovirus B19 infection with new onset of acute lymphoblastic and myeloblastic leukaemia. Methods: Cerebrospinal…”
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Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21) by Moorman, Anthony V., Richards, Susan M., Robinson, Hazel M., Strefford, Jon C., Gibson, Brenda E.S., Kinsey, Sally E., Eden, Tim O.B., Vora, Ajay J., Mitchell, Christopher D., Harrison, Christine J.

“…Patients with acute lymphoblastic leukemia (ALL) and an intrachromosomal amplification of chromosome 21 (iAMP21) comprise a novel and distinct biological…”
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Comparison of allogeneic transplant versus chemotherapy for relapsed childhood acute lymphoblastic leukaemia in the MRC UKALL R1 trial by Harrison, G., Richards, S., Lawson, S., Darbyshire, P., Pinkerton, R., Stevens, R., Oakhill, A., Eden, O. B.

“…Background Although reinduction rates are good for children with relapsed acute lymphoblastic leukaemia there is no consensus on whether bone marrow…”
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A survey of current practice with regard to oral care for children being treated for cancer by Glenny, A.M, Gibson, F, Auld, E, Coulson, S, Clarkson, J.E, Craig, J.V, Eden, O.B, Worthington, H.V, Pizer, B

“…The aim of the study was to establish current UK oral care practice for children with cancer. A telephone survey of all 22 United Kingdom Children's Cancer…”
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