Search Results - "Eden, Kristin"

Beyond the inflammasome: regulatory NOD-like receptor modulation of the host immune response following virus exposure by Coutermarsh-Ott, Sheryl, Eden, Kristin, Allen, Irving Coy

“…A complex interaction exists between elements of the host innate immune system and viral pathogens. It is essential that the host mount a robust immune…”
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Antibiotics ameliorate lupus-like symptoms in mice by Mu, Qinghui, Tavella, Vincent J., Kirby, Jay L., Cecere, Thomas E., Chung, Matthias, Lee, Jiyoung, Li, Song, Ahmed, S. Ansar, Eden, Kristin, Allen, Irving Coy, Reilly, Christopher M., Luo, Xin M.

“…Gut microbiota and the immune system interact to maintain tissue homeostasis, but whether this interaction is involved in the pathogenesis of systemic lupus…”
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An integrated pre-clerkship curriculum to build cognitive medical schema: It's not just about the content by LeClair, Renée J, Cleveland, Jennifer L, Eden, Kristin, Binks, Andrew P

“…Both physiology and pathophysiology are essential disciplines in health professional education however, clinicians do not use this knowledge in isolation…”
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EGR2 Deletion Suppresses Anti-DsDNA Autoantibody and IL-17 Production in Autoimmune-Prone B6/lpr Mice: A Differential Immune Regulatory Role of EGR2 in B6/lpr Versus Normal B6 Mice by Dai, Rujuan, Wang, Zhuang, Heid, Bettina, Eden, Kristin, Reilly, Christopher M., Ahmed, S. Ansar

“…Previous studies have reported that deletion of the transcription factor, early growth response protein 2 (EGR2), in normal C57BL/6 (B6) resulted in the…”
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NLRX1 Deficiency Alters the Gut Microbiome and Is Further Exacerbated by Adherence to a Gluten-Free Diet by Morrison, Holly A, Liu, Yang, Eden, Kristin, Nagai-Singer, Margaret A, Wade, Paul A, Allen, Irving C

“…Patients with gluten sensitivities present with dysbiosis of the gut microbiome that is further exacerbated by a strict adherence to a gluten-free diet (GFD)…”
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Noncanonical NF-κB Signaling Upregulation in Inflammatory Bowel Disease Patients is Associated With Loss of Response to Anti-TNF Agents by Nguyen, Vu Q., Eden, Kristin, Morrison, Holly A., Sammons, Megan B., Knight, Kristin K., Sorrentino, Siena, Brock, Rebecca M., Grider, Douglas J., Allen, Irving C., Sorrentino, Dario

“…Objectives: Targeting tumor necrosis factor (TNF) with biologic agents, such as infliximab and adalimumab, is a widely used and effective therapeutic strategy…”
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Selective Histone Deacetylase 6 Inhibition Normalizes B Cell Activation and Germinal Center Formation in a Model of Systemic Lupus Erythematosus by Ren, Jingjing, Catalina, Michelle D, Eden, Kristin, Liao, Xiaofeng, Read, Kaitlin A, Luo, Xin, McMillan, Ryan P, Hulver, Matthew W, Jarpe, Matthew, Bachali, Prathyusha, Grammer, Amrie C, Lipsky, Peter E, Reilly, Christopher M

“…Autoantibody production by plasma cells (PCs) plays a pivotal role in the pathogenesis of systemic lupus erythematosus (SLE). The molecular pathways by which B…”
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Quaternary Ammonium Compound Disinfectants Reduce Lupus-Associated Splenomegaly by Targeting Neutrophil Migration and T-Cell Fate by Abdelhamid, Leila, Cabana-Puig, Xavier, Mu, Qinghui, Moarefian, Maryam, Swartwout, Brianna, Eden, Kristin, Das, Prerna, Seguin, Ryan P, Xu, Libin, Lowen, Sarah, Lavani, Mital, Hrubec, Terry C, Jones, Caroline N, Luo, Xin M

“…Hypersensitivity reactions and immune dysregulation have been reported with the use of quaternary ammonium compound disinfectants (QACs). We hypothesized that…”
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Ultrasound-guided noninvasive pancreas ablation using histotripsy: feasibility study in an in vivo porcine model by Gannon, Jessica, Imran, Khan Mohammad, Hendricks-Wenger, Alissa, Edwards, Michael, Covell, Hannah, Ruger, Lauren, Singh, Neha, Nagai-Singer, Margaret, Tintera, Benjamin, Eden, Kristin, Mendiratta-Lala, Mishal, Vidal-Jove, Joan, Luyimbazi, David, Larson, Martha, Clark-Deener, Sherrie, Coutermarsh-Ott, Sheryl, Allen, Irving C, Vlaisavljevich, Eli

“…Pancreatic cancer is a malignant disease associated with poor survival and nearly 80% present with unresectable tumors. Treatments such as chemotherapy and…”
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Noncanonical NF-κB signaling and the essential kinase NIK modulate crucial features associated with eosinophilic esophagitis pathogenesis by Eden, Kristin, Rothschild, Daniel E, McDaniel, Dylan K, Heid, Bettina, Allen, Irving C

“…Eosinophilic esophagitis (EoE) is an allergic disease of the esophagus driven by T cell and eosinophil responses to dietary allergens, resulting in chronic…”
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Cerebral oligodendroglioma mimicking intraventricular neoplasia in three dogs by Rissi, Daniel R., Levine, Jonathan M., Eden, Kristin B., Watson, Victoria E., Griffin, John F., Edwards, John F., Porter, Brian F.

“…Oligodendroglioma is one of the most common primary central nervous system neoplasms of dogs. It is often diagnosed in older, brachycephalic breeds, and…”
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Case Report: Disorder of Sexual Development in a Chinese Crested Dog With XX/XY Leukocyte Chimerism and Mixed Cell Testicular Tumors by Schwartz, Rebecca, Sugai, Nicole J., Eden, Kristin, Castaneda, Caitlin, Jevit, Matthew, Raudsepp, Terje, Cecere, Julie T.

“…A 10-year-old intact female Chinese Crested dog was presented for evaluation and further diagnostics due to persistent symptoms of vulvar swelling, vaginal…”
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Congenital dystrophic epidermolysis bullosa (DEB) in Sprague Dawley rats: a case series by Eden, Kristin B., Peterson, Ashley, Payne, Harold R., Corapi, Wayne V., Mansell, Joanne, Hoffman, Aline Rodrigues

“…Background Epidermolysis bullosa is a rare skin disease caused by defects in the basement membrane and/or other dermoepidermal junction components…”
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Adoptive Transfer Colitis by Eden, Kristin

“…Lymphocytes are an important component of inflammatory bowel disease (IBD) pathogenesis. T cells in particular are potent inducers of inflammation in this…”
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Nasoseptal Flap for Skull Base Reconstruction in a Three-Year-Old Child With Nasofrontal Meningoencephalocele by Eden, Jördis Kristin, Böttcher, Arne, Betz, Christian Stephan

“…Congenital anterior skull base defects with meningoencephaloceles causing nasal obstruction and cerebrospinal fluid (CSF) rhinorrhea are rare clinical…”
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Mesenteric cryptococcal granuloma in a dog caused by Cryptococcus neoformans var. grubii by Cook, Jennifer R, Russell, Karen E, Eden, Kristin B, Rodrigues-Hoffmann, Aline

“…Although cryptococcosis is usually associated with respiratory and neurologic signs in domestic species (such as sneeze, cough, nasal discharge, seizures,…”
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Silver-Colloid-Nucleated Cytochrome c Superstructures Encapsulated in Silica Nanoarchitectures by Wallace, Jean Marie, Dening, Brett M, Eden, Kristin B, Stroud, Rhonda M, Long, Jeffrey W, Rolison, Debra R

“…We recently discovered that self-organized superstructures of the heme protein cytochrome c (cyt. c) are nucleated in buffer by gold nanoparticles. The protein…”
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Localizing the expression of Piezo2 in healthy and diseased lung tissue by Hennis, Lauren, Hambright, Parker, Eden, Kristin, Binks, Andrew, LeClair, Renee

“…Intractable air hunger remains one of the most impactful symptoms of chronic cardiopulmonary disease and current pharmacological management remains limited…”
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Emerging Roles for Noncanonical NF-κB Signaling in the Modulation of Inflammatory Bowel Disease Pathobiology by McDaniel, Dylan K, Eden, Kristin, Ringel, Veronica M, Allen, Irving C

“…Crohn's disease and ulcerative colitis are common and debilitating manifestations of inflammatory bowel disease (IBD). IBD is characterized by a radical…”
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EGR2 deletion displays similar and differential effects on immunological development and function in autoinflammation-prone B6/lpr and normal B6 mice by Dai, Rujuan, Wang, Zhuang, Heid, Bettina, Eden, Kristin, Reilly, Christopher M, Ahmed, S Ansar

“…Abstract Transcription factor early growth response protein 2 (EGR2) prevents the development of lupus-like autoimmune disease in C57BL/6 (B6) mice by…”
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