Search Results - "Edem, Edem Ekpenyong"

Ketamine abrogates sensorimotor deficits and cytokine dysregulation in a chronic unpredictable mild stress model of depression by Edem, Edem Ekpenyong, Anyanwu, Collins-Kevin Chukwudi, Nebo, Kate Eberechukwu, Akinluyi, Elizabeth Toyin, Fafure, Adedamola Adediran, Ishola, Azeez Olakunle, Enye, Linus Anderson

“…Major depressive disorder (MDD) is a serious mental disorder with influence across the functional systems of the body. The pathogenesis of MDD has been known…”
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Quercetin abrogates lipopolysaccharide-induced depressive-like symptoms by inhibiting neuroinflammation via microglial NLRP3/NFκB/iNOS signaling pathway by Adeoluwa, Olusegun Adebayo, Olayinka, Juliet Nneda, Adeoluwa, Gladys Onyinye, Akinluyi, Elizabeth Toyin, Adeniyi, Funmilayo Racheal, Fafure, Adedamola, Nebo, Kate, Edem, Edem Ekpenyong, Eduviere, Anthony Taghogho, Abubakar, Badamasi

“…Major depressive disorder is a serious psychiatric illness having serious damaging effect on the quality of life of suffers. Quercetin is a plant flavonoid,…”
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Black seed oil reverses chronic antibiotic-mediated depression and social behaviour deficits via modulation of hypothalamic mitochondrial-dependent markers and insulin expression by Adedokun, Mujeeb Adekunle, Enye, Linus Anderson, Akinluyi, Elizabeth Toyin, Ajibola, Toheeb Adesumbo, Edem, Edem Ekpenyong

“…Chronic antibiotic use has been reported to impair mitochondrial indices, hypothalamus-mediated metabolic function, and amygdala-regulated emotional processes…”
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Tiger nut/coconut dietary intervention as antidotal nutritional remediation strategy against neurobehavioural deficits following organophosphate-induced gut-brain axis dysregulation in mice by Enye, Linus Anderson, Edem, Edem Ekpenyong, Onyeogaziri, Lydia Ijeoma, Yusuf, Augustine, Ikpade, Bliss Oluwafunmi, Ikuelogbon, Daniel Akinwale, Kunlere, Oladunni Eunice, Adedokun, Mujeeb Adekunle

“…Organophosphate poisoning remains a global health crisis without efficacious treatments to prevent neurotoxicity. We examined whether antidotal tiger nut and…”
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Altered circadian rhythms effects on anxiety, locomotor activity, serotonin and nitric oxide levels in the prefrontal cortex of juvenile and adult rats by Obajuluwa, Adejoke Olukayode, Lech, James Chrystopher, Afolabi, Olakunle Bamikole, Obajuluwa, Tiwalola Madoc, Babafemi, Laoye John, Edem, Edem Ekpenyong

“…Background Dementia and Alzheimer’s disease (AD) can be exacerbated by irregular sleep‐wake cycles, and age may be a risk factor. This study compared…”
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Prolonged ketamine therapy differentially rescues psychobehavioural deficits via modulation of nitro-oxidative stress and oxytocin receptors in the gut-brain-axis of chronically-stressed mice by Edem, Edem Ekpenyong, Oguntala, Oluwatomisn Adeyosola, Ikuelogbon, Daniel Akinwale, Nebo, Kate Eberechukwu, Fafure, Adedamola Adediran, Akinluyi, Elizabeth Toyin, Isaac, Godspower Tochukwu, Kunlere, Oladunni Eunice

“…Ketamine is an anaesthetic known to have short but rapid-acting anti-depressant effects; however, the neurobehavioural effects of its prolonged use and its…”
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Combined Exposure to Chronic Sleep Deprivation and Caffeine Potentiates Behavioural Deficits by Altering Neurochemical Profile and Synaptophysin Expression in Long-Evans Rats by Edem, Edem Ekpenyong, Okhonmina, Uyi Emmanuel, Nebo, Kate Eberechukwu, Akinluyi, Elizabeth Toyin, Ikuelogbon, Daniel Akinwale, Fafure, Adedamola Adediran, Olabiyi, Ayodeji Augustine, Adedokun, Mujeeb Adekunle

“…Using the Unpredictable Chronic Sleep Deprivation (UCSD) paradigm we developed, the combined effects of chronic sleep deprivation and high caffeine intake on…”
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Neurobehavioral deficits, histoarchitectural alterations, parvalbumin neuronal damage and glial activation in the brain of male Wistar rat exposed to Landfill leachate by Levi, Usende Ifukibot, Bintu, Mofio M., Daniella, Osinachi Chinonyerem, Oyenike, Oyelowo-Abdulraheem Fatima, Agbonu, Adikpe Oluwa, Adedamola, Azeez Mariam, Ndidi, Enefe, Saka, Sanni Fatimah, Gela, Beselia V., Mbagwu, Smart I., Edem, Edem Ekpenyong, Olukayode, Olopade James, James, Connor

“…Concerns about inappropriate disposal of waste into unsanitary municipal solid waste landfills around the world have been on the increase, and this poses a…”
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Lactobacillus plantarum mitigates sexual-reproductive deficits by modulating insulin receptor expression in the hypothalamic-pituitary-testicular axis of hyperinsulinemic mice by Edem, Edem Ekpenyong, Nathaniel, Blessing Uyo, Nebo, Kate Eberechukwu, Obisesan, Abiola Oluwatosin, Olabiyi, Ayodeji Augustine, Akinluyi, Elizabeth Toyin, Ishola, Azeez Olakunle

“…Hyperinsulinemia increases the risk factor of diabetes and infertility at a manifold. has several medical significances with limited reports. Hence, this study…”
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