Search Results - "Edelstein, Jasmine N."
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Analysis of Pre-existing IgG and IgM Antibodies against Polyethylene Glycol (PEG) in the General Population
Published in Analytical chemistry (Washington) (06-12-2016)“…Circulating antibodies (Ab) that specifically bind polyethylene glycol (PEG), a biocompatible polymer routinely used in protein and nanoparticle therapeutics,…”
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AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines
Published in Nature communications (23-06-2021)“…Though AsCas12a fills a crucial gap in the current genome editing toolbox, it exhibits relatively poor editing efficiency, restricting its overall utility…”
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Author Correction: AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines
Published in Nature communications (19-07-2021)Get full text
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Human plasma cells engineered to secrete bispecifics drive effective in vivo leukemia killing
Published in Molecular therapy (07-08-2024)“…Bispecific antibodies are an important tool for the management and treatment of acute leukemias. As a next step toward clinical translation of engineered…”
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409 Development of ex vivo precision gene engineered B cell medicines that produce highly active and sustained levels of transgenic anti-tumor biologics
Published in Journal for immunotherapy of cancer (02-11-2023)“…BackgroundBispecific T Cell Engagers (BiTEs), consisting of an anti-CD3 scFv fused to an anti-tumor antigen scFv, are highly effective in the treatment of…”
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409 Development ofex vivo precision gene engineered B cell medicines that produce highly active and sustained levels of transgenic anti-tumor biologics
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundBispecific T Cell Engagers (BiTEs), consisting of an anti-CD3 scFv fused to an anti-tumor antigen scFv, are highly effective in the treatment of…”
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