Search Results - "Edelmann, S E"
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Regulation of the cellular localization and signaling properties of the alpha(1B)- and alpha(1D)-adrenoceptors by agonists and inverse agonists
Published in Molecular pharmacology (01-04-2000)“…The regulation of the cellular distribution and intracellular signaling properties of the alpha(1B)- and alpha(1D)- adrenoceptor (alpha(1)-AR) subtypes was…”
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Immunocytochemical localization of the alpha-1B adrenergic receptor and the contribution of this and the other subtypes to vascular smooth muscle contraction: analysis with selective ligands and antisense oligonucleotides
Published in The Journal of pharmacology and experimental therapeutics (01-11-1997)“…The contribution of the alpha-1B adrenergic receptor (AR) to vascular smooth muscle contraction has been assessed using a combination of immunological,…”
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The protective roles of nitric oxide and superoxide dismutase in adriamycin-induced cardiotoxicity
Published in Cardiovascular research (2006)“…Treatment with adriamycin (ADR) is associated with cardiotoxicity mediated through the generation of superoxide (O2*-). Because nitric oxide (*NO) reacts with…”
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Differences in the cellular localization and agonist-mediated internalization properties of the alpha(1)-adrenoceptor subtypes
Published in Molecular pharmacology (01-05-2002)“…The cellular localization, agonist-mediated internalization, and desensitization properties of the alpha(1)-adrenoceptor (alpha(1)-AR) subtypes conjugated with…”
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Expression of multiple alpha1-adrenoceptors on vascular smooth muscle: correlation with the regulation of contraction
Published in The Journal of pharmacology and experimental therapeutics (01-07-1999)“…Previous work has shown that the genes encoding each alpha1-adrenoceptor subtype are coexpressed throughout the peripheral vascular system. We have evaluated…”
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The agonism and synergistic potentiation of weak partial agonists by triethylamine in alpha 1-adrenergic receptor activation: evidence for a salt bridge as the initiating process
Published in Molecular pharmacology (01-04-1998)“…Alpha 1-adrenergic receptor (AR) activation is thought to be initiated by disruption of a constraining interhelical salt bridge (). Disruption of this salt…”
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