Search Results - "Edelman, M. J."

Second ESMO consensus conference on lung cancer: pathology and molecular biomarkers for non-small-cell lung cancer by Kerr, K.M., Bubendorf, L., Edelman, M.J., Marchetti, A., Mok, T., Novello, S., O'Byrne, K., Stahel, R., Peters, S., Felip, E., Stahel, Rolf, Felip, Enriqueta, Peters, Solange, Kerr, Keith, Besse, Benjamin, Vansteenkiste, Johan, Eberhardt, Wilfried, Edelman, Martin, Mok, Tony, O'Byrne, Ken, Novello, Silvia, Bubendorf, Lukas, Marchetti, Antonio, Baas, Paul, Reck, Martin, Syrigos, Konstantinos, Paz-Ares, Luis, Smit, Egbert F., Meldgaard, Peter, Adjei, Alex, Nicolson, Marianne, Crinò, Lucio, Van Schil, Paul, Senan, Suresh, Faivre-Finn, Corinne, Rocco, Gaetano, Veronesi, Giulia, Douillard, Jean-Yves, Lim, Eric, Dooms, Christophe, Weder, Walter, De Ruysscher, Dirk, Le Pechoux, Cecile, De Leyn, Paul, Westeel, Virginie

“…To complement the existing treatment guidelines for all tumour types, ESMO organises consensus conferences to focus on specific issues in each type of tumour…”
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Influence of body mass index on the response to asthma controller agents by Peters-Golden, M, Swern, A, Bird, S. S, Hustad, C. M, Grant, E, Edelman, J. M

“…The incidence of asthma has been positively associated with obesity. Asthma comprises diverse "phenotypes" reflecting heterogeneity in a number of…”
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A randomized, phase III multicenter trial of gemcitabine in combination with carboplatin or paclitaxel versus paclitaxel plus carboplatin in patients with advanced or metastatic non-small-cell lung cancer by Treat, J.A., Gonin, R., Socinski, M.A., Edelman, M.J., Catalano, R.B., Marinucci, D.M., Ansari, R., Gillenwater, H.H., Rowland, K.M., Comis, R.L., Obasaju, C.K., Belani, C.P.

“…Paclitaxel–carboplatin is used as the standard regimen for patients with advanced or metastatic non-small-cell lung cancer (NSCLC). This trial was designed to…”
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Comparative Effects of CT Imaging Measurement on RECIST End Points and Tumor Growth Kinetics Modeling by Li, CH, Bies, RR, Wang, Y, Sharma, MR, Karovic, S, Werk, L, Edelman, MJ, Miller, AA, Vokes, EE, Oto, A, Ratain, MJ, Schwartz, LH, Maitland, ML

“…Quantitative assessments of tumor burden and modeling of longitudinal growth could improve phase II oncology trials. To identify obstacles to wider use of…”
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Population impact of losartan use on stroke in the European Union (EU): Projections from the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study by Dahlöf, B, Burke, T A, Krobot, K, Carides, G W, Edelman, J M, Devereux, R B, Diener, H-C

“…The Losartan Intervention for Endpoint reduction in hypertension (LIFE) study was designed to compare losartan- vs atenolol-based antihypertensive treatment on…”
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Distribution of therapeutic response in asthma control between oral montelukast and inhaled beclomethasone by Baumgartner, R.A, Martinez, G, Edelman, J.M, Rodriguez Gomez, G.G, Bernstein, M, Bird, S, Angner, R, Polis, A, Dass, S.B, Lu, S, Reiss, T.F

“…The distribution of responses in study populations provides a novel method of comparing the benefit of two treatments. This 6-week, randomised,…”
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Statistical controversies in clinical research: futility analyses in oncology–lessons on potential pitfalls from a randomized controlled trial by Lesaffre, E., Edelman, M.J., Hanna, N.H., Park, K., Thatcher, N., Willemsen, S., Gaschler-Markefski, B., Kaiser, R., Manegold, C.

“…Pre-planned futility analyses are commonly used in oncology studies. The LUME-Lung 2 study (NCT00806819; 1199.14) was stopped early based on a pre-planned,…”
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Analysis of montelukast in mild persistent asthmatic patients with near-normal lung function by BARNES, N., WEI, L.X., REISS, T.F., LEFF, J.A., SHINGO, S., YU, C., EDELMAN, J.M.

“…Few studies have specifically evaluated controller therapy in patients with mild persistent asthma. We used a subgroup analysis to investigate the effects of…”
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Regression of Electrocardiographic Left Ventricular Hypertrophy During Antihypertensive Treatment and the Prediction of Major Cardiovascular Events by Okin, Peter M, Devereux, Richard B, Jern, Sverker, Kjeldsen, Sverre E, Julius, Stevo, Nieminen, Markku S, Snapinn, Steven, Harris, Katherine E, Aurup, Peter, Edelman, Jonathan M, Wedel, Hans, Lindholm, Lars H, Dahlöf, Björn, LIFE Study Investigators, for the

“…CONTEXT Electrocardiographic left ventricular hypertrophy (LVH) is a strong predictor of cardiovascular (CV) morbidity and mortality. However, the predictive…”
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Regression of hypertensive left ventricular hypertrophy by losartan compared with atenolol: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial by Devereux, Richard B, Dahlöf, Björn, Gerdts, Eva, Boman, Kurt, Nieminen, Markku S, Papademetriou, Vasilios, Rokkedal, Jens, Harris, Katherine E, Edelman, Jonathan M, Wachtell, Kristian

“…An echocardiographic substudy of the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial was designed to test the ability of losartan to…”
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RB Status as a Determinant of Response to UCN-01 in Non-Small Cell Lung Carcinoma by MACK, P. C, GANDARA, D. R, BOWEN, C, EDELMAN, M. J, PAGLIERONI, T, SCHNIER, J. B, GELMANN, E. P, GUMERLOCK, P. H

“…7-Hydroxystaurosporine (UCN-01), a protein kinase inhibitor in clinical development, demonstrates potent antineoplastic activity. To determine whether specific…”
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A study of losartan, alone or with hydrochlorothiazide vs nifedipine GITS in elderly patients with diastolic hypertension by CONLIN, P. R, ELKINS, M, LISS, C, VRECENAK, A. J, BARR, E, EDELMAN, J. M

“…We conducted a randomised, double-blind, parallel design study comparing the efficacy and tolerability of the angiotensin II receptor antagonist, losartan,…”
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Phase I/II study of paclitaxel, carboplatin, and methotrexate in advanced transitional cell carcinoma: a well-tolerated regimen with activity independent of p53 mutation by Edelman, Martin J, Meyers, Frederick J, Miller, Tim R, Williams, Stephen G, Gandour-Edwards, Regina, deVere White, Ralph W

“…Objectives. To evaluate the feasibility and activity of paclitaxel, carboplatin, and methotrexate in advanced transitional cell carcinoma (TCC) of the…”
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Regression of electrocardiographic left ventricular hypertrophy by losartan versus atenolol: The Losartan Intervention for Endpoint reduction in Hypertension (LIFE) Study by Okin, Peter M, Devereux, Richard B, Jern, Sverker, Kjeldsen, Sverre E, Julius, Stevo, Nieminen, Markku S, Snapinn, Steven, Harris, Katherine E, Aurup, Peter, Edelman, Jonathan M, Dahlof, Bjorn

“…Electrocardiographic left ventricular hypertrophy (LVH) predicts cardiovascular morbidity and mortality, and regression of ECG LVH may predict improved…”
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The potential for reintroduction of tumor cells during intraoperative blood salvage: Reduction of risk with use of the RC-400 leukocyte depletion filter by Edelman, Martin J., Potter, Paul, Mahaffey, Kevin G., Frink, Richard, Leidich, Raymond B.

“…Intraoperative autotransfusion of shed blood is widely utilized in surgery. However, several studies have raised concern about the transmission of tumor cells…”
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Serotonergic blockade in the treatment of the cancer anorexia‐cachexia syndrome by Edelman, Martin J., Gandara, David R., Meyers, Frederick J., Ishii, Rie, O'Mahony, Michael, Uhrich, Margaret, Lauder, Ignacio, Houston, Joan, Gietzen, Dorothy W.

“…BACKGROUND Imbalanced amino acid diets in animals rapidly produce anorexia and weight loss. Blockade of type 3 serotonergic receptors (5HT3) can ameliorate…”
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Efficacy and tolerability of losartan versus enalapril alone or in combination with hydrochlorothiazide in patients with essential hypertension by Townsend, Raymond, Haggert, Brian, Liss, Charles, Edelman, Jonathan M.

“…The antihypertensive effects and the tolerability of losartan and enalapril given alone or in combination with hydrochlorothiazide (HCTZ) were compared in a…”
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Greater Regression of Electrocardiographic Left Ventricular Hypertrophy During Hydrochlorothiazide Therapy in Hypertensive Patients by Okin, Peter M., Hille, Darcy A., Kjeldsen, Sverre E., Lindholm, Lars H., Edelman, Jonathan M., Dahlöf, Björn, Devereux, Richard B.

“…Background Treatment of hypertensive patients with a losartan-based regimen was associated with greater regression of electrocardiographic (ECG) left…”
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Efficacy, tolerability, and quality of life of losartan, alone or with hydrochlorothiazide, versus nifedipine GITS in patients with essential hypertension by Weir, Matthew R., Elkins, Michelle, Liss, Charles, Vrecenak, Arthur J., Barr, Eliav, Edelman, Jonathan M.

“…A randomized, double-masked, parallel-group, multicenter clinical trial was conducted to compare the efficacy, tolerability, and effects on quality of life…”
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Promising new agents in the treatment of non-small cell lung cancer by EDELMAN, M. J, GANDARA, D. R

“…A number of new drugs and drug classes have recently become available for clinical testing which demonstrate significant antitumor activity in non-small cell…”
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